- Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics
[作者：Hirata, K; Maruyama, T; Watanabe, H; Maeda, H; Nakajou, K; Iwao, Y; Ishima, Y; Katsumi, H; Hashida, M; Otagiri, M,期刊：Journal of controlled release, 页码：9-16 , 文章类型： Article，,卷期：2010年145-1]
- Human serum albumin (HSA), a non-glycosylated protein, is widely employed as carrier for drug delivery systems. A series of recombinant, mannosylated-HSA mutants (Man-rHSAs: D63N, A320T and D494N) and their triple mutant...
- Improved tumor-targeting drug delivery and therapeutic efficacy by cationic liposome modified with truncated bFGF peptide
[作者：Chen, XA; Wang, XH; Wang, YS; Yang, L; Hu, J; Xiao, WJ; Fu, A; Cai, LL; Li, X; Ye, X; Liu, YL; Wu, WS; Shao, XM; Mao, YQ; Wei, YQ; Chen, LJ,期刊：Journal of controlled release, 页码：17-25 , 文章类型： Article，,卷期：2010年145-1]
- Fibroblast growth factor receptors (FGFRs), overexpressed on the surface of a variety of tumor cells and on tumor neovasculature in situ, are potential targets for tumor- and vascular-targeting therapy. This study aimed ...
- Delivery of DNA and siRNA by novel gemini-like amphiphilic peptides
[作者：Damen, M; Aarbiou, J; van Dongen, SFM; Buijs-Offerman, RM; Spijkers, PP; van den Heuvel, M; Kvashnina, K; Nolte, RJM; Scholte, BJ; Feiters, MC,期刊：Journal of controlled release, 页码：33-39 , 文章类型： Article，,卷期：2010年145-1]
- We report the design, synthesis, and characterization of a novel type of cationic lipopeptide, gemini-like amphiphilic peptides or 'geminoids'. As an example, the SPKR peptide, inspired by biological nucleic acid binding...
- The correlation between acoustic cavitation and sonoporation involved in ultrasound-mediated DNA transfection with polyethylenimine (PEI) in vitro
[作者：Qiu, YY; Luo, Y; Zhang, YL; Cui, WC; Zhang, D; Wu, JR; Zhang, JF; Tu, JA,期刊：Journal of controlled release, 页码：40-48 , 文章类型： Article，,卷期：2010年145-1]
- Previous studies have demonstrated that the efficiency of gene/drug delivery can be enhanced under ultrasound (US) exposure with the presence of US contrast agent microbubbles, due to the acoustic cavitation-induced sono...
- Sialic acid and glycopeptides conjugated PLGA nanoparticles for central nervous system targeting: In vivo pharmacological evidence and biodistribution
[作者：Tosi, G; Vergoni, AV; Ruozi, B; Bondioli, L; Badiali, L; Rivasi, F; Costantino, L; Forni, F; Vandelli, MA,期刊：Journal of controlled release, 页码：49-57 , 文章类型： Article，,卷期：2010年145-1]
- Polymeric nanoparticles (Np) have been considered as strategic carriers for brain targeting. Specific ligands on the surface allowed the Np to cross the Blood-Brain Barrier (BBB) carrying model drugs within the brain dis...
- Release profile characteristics of biodegradable-polymer-coated drug particles fabricated by dual-capillary electrospray
[作者：Lee, YH; Mei, F; Bai, MY; Zhao, S; Chen, DR,期刊：Journal of controlled release, 页码：58-65 , 文章类型： Article，,卷期：2010年145-1]
- This study describes one-step synthesis of coated particles by a dual-capillary electrospray (ES) system to produce monodisperse PLGA-coated drug particles. Different from a single-capillary ES system, the dual-capillary...
- Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma
[作者：Loi, M; Marchio, S; Becherini, P; Di Paolo, D; Soster, M; Curnis, F; Brignole, C; Pagnan, G; Perri, P; Caffa, I; Longhi, R; Nico, B; Bussolino, F; Gambini, C; Ribatti, D; Cilli, M; Arap, W; Pasqualini, R; Allen, TM; Corti, A; Ponzoni, M; Pastorino, F,期刊：Journal of controlled release, 页码：66-73 , 文章类型： Article，,卷期：2010年145-1]
- The therapeutic index of anti-cancer drugs is increased when encapsulating them in tumor-targeted liposomes. Liposome-entrapped doxorubicin (DXR), targeting the tumor vasculature marker, aminopeptidase N (APN), displayed...
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