- Silver nano - A trove for retinal therapies
[作者：Kalishwaralal, K; BarathManiKanth, S; Pandian, SRK; Deepak, V; Gurunathan, S,期刊：Journal of controlled release, 页码：76-90 , 文章类型： Review，,卷期：2010年145-2]
- Pathological retinal angiogenesis (neovascularization) is one of the most feared complications among retinal diseases, leading to visual impairment and irreversible blindness. Recent findings made by us on therapeutic ap...
- A novel approach to deliver anticancer drugs to key cell types in tumors using a PDGF receptor-binding cyclic peptide containing carrier
[作者：Prakash, J; de Jong, E; Post, E; Gouw, ASH; Beljaars, L; Poelstra, K,期刊：Journal of controlled release, 页码：91-101 , 文章类型： Article，,卷期：2010年145-2]
- Tumor stromal cells have been recently recognized to contribute to tumor growth. Therefore, we hypothesized that delivery of anticancer drugs to these cells in addition to the tumor cells might treat cancer more effectiv...
- Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response
[作者：Henriksen-Lacey, M; Christensen, D; Bramwell, VW; Lindenstrom, T; Agger, EM; Andersen, P; Perrie, Y,期刊：Journal of controlled release, 页码：102-108 , 文章类型： Article，,卷期：2010年145-2]
- With respect to liposomes as delivery vehicles and adjuvants for vaccine antigens, the role of vesicle surface charge remains disputed. In the present study we investigate the influence of liposome surface charge and ant...
- VEGF-induced angiogenesis following localized delivery via injectable, low viscosity poly(trimethylene carbonate)
[作者：Amsden, BG; Timbart, L; Marecak, D; Chapanian, R; Tse, MY; Pang, SC,期刊：Journal of controlled release, 页码：109-115 , 文章类型： Article，,卷期：2010年145-2]
- The purpose of this study was to examine the potential of low molecular weight poly(trimethylene carbonate) for localized vascular endothelial growth factor (VEGF) delivery. Poly(trimethylene carbonate) of various molecu...
- Fractional laser as a tool to enhance the skin permeation of 5-aminolevulinic acid with minimal skin disruption: A comparison with conventional erbium:YAG laser
[作者：Lee, WR; Shen, SC; Pai, MH; Yang, HH; Yuan, CY; Fang, JY,期刊：Journal of controlled release, 页码：124-133 , 文章类型： Article，,卷期：2010年145-2]
- The aim of this study was to examine the in vitro skin delivery and in vivo protoporphyrin IX (PpIX) accumulation of topically applied 5-aminolevulinic acid (ALA) enhanced by a fractional laser pretreatment. This was ach...
- Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown
[作者：Kim, HJ; Ishii, A; Miyata, K; Lee, Y; Wu, SR; Oba, M; Nishiyama, N; Kataoka, K,期刊：Journal of controlled release, 页码：141-148 , 文章类型： Article，,卷期：2010年145-2]
- Applications of siRNA for cancer therapy have been spotlighted in recent years, but the rational design of efficient siRNA delivery carriers is still controversial, especially because of possible toxicity of the carrier ...
- A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides
[作者：Trabulo, S; Resina, S; Simoes, S; Lebleu, B; de Lima, MCP,期刊：Journal of controlled release, 页码：149-158 , 文章类型： Article，,卷期：2010年145-2]
- Modulation of pre-mRNA splicing by steric-block oligonucleotides constitutes a promising strategy for the treatment of many diseases, but requires efficient delivery to cell nuclei. In the present study, we evaluated the...
- Pegylated poly-L-arginine derivatives of chitosan for effective delivery of siRNA
[作者：Noh, SM; Park, MO; Shim, G; Han, SE; Lee, HY; Huh, JH; Kim, MS; Choi, JJ; Kim, K; Kwon, IC; Kim, JS; Baek, KH; Oh, YK,期刊：Journal of controlled release, 页码：159-164 , 文章类型： Article，,卷期：2010年145-2]
- For delivery of siRNA, chitosan (CS) was derivatized with poly-L-arginine (PLR) and polyethylene glycol (PEG). The formation of polyplexes with siRNA was confirmed by gel retardation. The PLR-grafted CS formed nanosized ...
- Downregulation of EGFR by a novel multivalent nanobody-liposome platform
[作者：Oliveira, S; Schiffelers, RM; van der Veeken, J; van der Meel, R; Vongpromek, R; Henegouwen, PMPVE; Storm, G; Roovers, RC,期刊：Journal of controlled release, 页码：165-175 , 文章类型： Article，,卷期：2010年145-2]
- The epidermal growth factor receptor (EGFR) is a recognized target for tumor therapy and monoclonal antibodies (mAbs, e.g. cetuximab) have been developed to inhibit receptor activation. Besides blocking ligand (e.g. EGF)...
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