- Investigational drugs for allergic rhinitis
[作者:Passalacqua, G; Compalati, E; Canonica, GW,期刊:Expert opinion on investigational drugs, 页码:93-103 , 文章类型: Review,,卷期:2010年19-1]
- Allergic rhinitis (AR) is a high-prevalence disease, triggered by an IgE-mediated reaction, and sustained by a complex inflammatory network of cells, mediators, and cytokines. When the exposure to allergens persists, the...
- Targeting cancer with phosphodiesterase inhibitors
[作者:Savai, R; Pullamsetti, SS; Banat, GA; Weissmann, N; Ghofrani, HA; Grimminger, F; Schermuly, RT,期刊:Expert opinion on investigational drugs, 页码:117-131 , 文章类型: Review,,卷期:2010年19-1]
- Importance of the field. For many cancers, there has been a shift from management with traditional, nonspecific cytotoxic chemotherapies to treatment with molecule-specific targeted therapies that are used either alone o...
- Darapladib
[作者:Bui, QT; Wilensky, RL,期刊:Expert opinion on investigational drugs, 页码:161-168 , 文章类型: Article,,卷期:2010年19-1]
- Importance of the field. Atherosclerosis is an inflammatory-immune mediated disease process. Plaque rupture is responsible for the clinical events of ischemic death, myocardial infarction, acute coronary syndromes and is...
- The efficacy and safety of telaprevir - a new protease inhibitor against hepatitis C virus
[作者:Gentile, I; Carleo, MA; Borgia, F; Castaldo, G; Borgia, G,期刊:Expert opinion on investigational drugs, 页码:151-159 , 文章类型: Article,,卷期:2010年19-1]
- Importance of the field. Hepatitis C virus (HCV) is the main agent of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma in the western world. It affects more than 170 million people worldwide. HCV treatment...
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