- The DNA replication checkpoint aids survival of plants deficient in the novel replisome factor ETG1
[作者：Takahashi, N; Lammens, T; Boudolf, V; Maes, S; Yoshizumi, T; De Jaeger, G; Witters, E; Inze, D; De Veylder, L,期刊：EMBO journal, 页码：1840-1851 , 文章类型： Article，,卷期：2008年27-13]
- Complete and accurate chromosomal DNA replication is essential for the maintenance of the genetic integrity of all organisms. Errors in replication are buffered by the activation of DNA stress checkpoints; however, in pl...
- A B-Myb complex containing clathrin and filamin is required for mitotic spindle function
[作者：Yamauchi, T; Ishidao, T; Nomura, T; Shinagawa, T; Tanaka, Y; Yonemura, S; Ishii, S,期刊：EMBO journal, 页码：1852-1862 , 文章类型： Article，,卷期：2008年27-13]
- B-Myb is one member of the vertebrate Myb family of transcription factors and is ubiquitously expressed. B-Myb activates transcription of a group of genes required for the G2/M cell cycle transition by forming the dREAM/...
- The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex
[作者：Song, MS; Song, SJ; Kim, SY; Oh, HJ; Lim, DS,期刊：EMBO journal, 页码：1863-1874 , 文章类型： Article，,卷期：2008年27-13]
- The tumour suppressor p53, which accumulates in response to DNA damage and induces cell-cycle arrest and apoptosis, has a key function in the maintenance of genome integrity. Under normal conditions, the antiproliferativ...
- Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1
[作者：Robert-Moreno, A; Guiu, J; Ruiz-Herguido, C; Lopez, ME; Ingles-Esteve, J; Riera, L; Tipping, A; Enver, T; Dzierzak, E; Gridley, T; Espinosa, L; Bigas, A,期刊：EMBO journal, 页码：1886-1895 , 文章类型： Article，,卷期：2008年27-13]
- Specific deletion of Notch1 and RBPjk in the mouse results in abrogation of definitive haematopoiesis concomitant with the loss of arterial identity at embryonic stage. As prior arterial determination is likely to be req...
- Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis
[作者：Sohn, SJ; Lewis, GM; Winoto, A,期刊：EMBO journal, 页码：1896-1906 , 文章类型： Article，,卷期：2008年27-13]
- The mitogen-activated protein kinases (MAPKs) ERK1/2, p38, and JNK are thought to determine survival-versus-death fate in developing thymocytes. However, this view was challenged by studies using 'MEK1-ERK1/2-specific' p...
- The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation
[作者：Baumli, S; Lolli, G; Lowe, ED; Troiani, S; Rusconi, L; Bullock, AN; Debreczeni, JE; Knapp, S; Johnson, LN,期刊：EMBO journal, 页码：1907-1918 , 文章类型： Article，,卷期：2008年27-13]
- The positive transcription elongation factor b (P-TEFb) (CDK9/cyclin T (CycT)) promotes mRNA transcriptional elongation through phosphorylation of elongation repressors and RNA polymerase II. To understand the regulation...
- Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis
[作者：Simon, GC; Schonteich, E; Wu, CC; Piekny, A; Ekiert, D; Yu, XZ; Gould, GW; Glotzer, M; Prekeris, R,期刊：EMBO journal, 页码：1791-1803 , 文章类型： Article，,卷期：2008年27-13]
- Cytokinesis is a highly regulated and dynamic event that involves the reorganization of the cytoskeleton and membrane compartments. Recently, FIP3 has been implicated in targeting of recycling endosomes to the mid-body o...
- Identification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signalling
[作者：Faresse, N; Colland, F; Ferrand, N; Prunier, C; Bourgeade, MF; Atfi, A,期刊：EMBO journal, 页码：1804-1815 , 文章类型： Article，,卷期：2008年27-13]
- The TGIF homoeodomain protein functions as an important negative regulator in the TGF-beta signalling pathway. The inhibitory function of TGIF is executed in part through its ability to sequester the tumour suppressor cy...
- The interaction network of the chaperonin CCT
[作者：Dekker, C; Stirling, PC; McCormack, EA; Filmore, H; Paul, A; Brost, RL; Costanzo, M; Boone, C; Leroux, MR; Willison, KR,期刊：EMBO journal, 页码：1827-1839 , 文章类型： Article，,卷期：2008年27-13]
- The eukaryotic cytosolic chaperonin containing TCP-1 (CCT) has an important function in maintaining cellular homoeostasis by assisting the folding of many proteins, including the cytoskeletal components actin and tubulin...
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