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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共14条记录   Transient receptor potential channels meet phosphoinositides [作者：Nilius, B; Owsianik, G; Voets, T,期刊：EMBO journal, 页码：2809-2816 , 文章类型： Article，,卷期：2008年27-21] Transient receptor potential (TRP) cation channels are unique cellular sensors that are involved in multiple cellular functions, ranging from transduction of sensory signals to the regulation of Ca2+ and Mg2+ homoeostasi... ATF6 modulates SREBP2-mediated lipogenesis (vol 23, pg 950, 2004) [作者：Zeng, LF; Lu, M; Mori, K; Luo, SZ; Lee, AS; Zhu, Y; Shyy, JYJ,期刊：EMBO journal, 页码：2941-2941 , 文章类型： Correction，,卷期：2008年27-21] Dissecting the role of Aurora A during spindle assembly (vol 27, pg 2567, 2008) [作者：Sardon, T; Peset, I; Petrova, B; Vernos, I,期刊：EMBO journal, 页码：2942-2942 , 文章类型： Correction，,卷期：2008年27-21] EFC/F-BAR proteins and the N-WASP-WIP complex induce membrane curvature-dependent actin polymerization [作者：Takano, K; Toyooka, K; Suetsugu, S,期刊：EMBO journal, 页码：2817-2828 , 文章类型： Article，,卷期：2008年27-21] Extended Fer-CIP4 homology (EFC)/FCH-BAR (F-BAR) domains generate and bind to tubular membrane structures of defined diameters that are involved in the formation and fission of endocytotic vesicles. Formin-binding protei... Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia [作者：Alcaraz, J; Xu, R; Mori, H; Nelson, CM; Mroue, R; Spencer, VA; Brownfield, D; Radisky, DC; Bustamante, C; Bissell, MJ,期刊：EMBO journal, 页码：2829-2838 , 文章类型： Article，,卷期：2008年27-21] In the mammary gland, epithelial cells are embedded in a 'soft' environment and become functionally differentiated in culture when exposed to a laminin-rich extracellular matrix gel. Here, we define the processes by whic... CTCF regulates cell cycle progression of alpha beta T cells in the thymus [作者：Heath, H; de Almeida, CR; Sleutels, F; Dingjan, G; van de Nobelen, S; Jonkers, I; Ling, KW; Gribnau, J; Renkawitz, R; Grosveld, F; Hendriks, RW; Galjart, N,期刊：EMBO journal, 页码：2839-2850 , 文章类型： Article，,卷期：2008年27-21] The 11-zinc finger protein CCCTC-binding factor ( CTCF) is a highly conserved protein, involved in imprinting, longrange chromatin interactions and transcription. To investigate its function in vivo, we generated mice wi... Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1 [作者：Herold, S; Hock, A; Herkert, B; Berns, K; Mullenders, J; Beijersbergen, R; Bernards, R; Eilers, M,期刊：EMBO journal, 页码：2851-2861 , 文章类型： Article，,卷期：2008年27-21] The Myc-associated zinc-finger protein, Miz1, activates transcription of the p21cip1 gene in response to UV irradiation. Miz1 associates with topoisomerase II binding protein1 (TopBP1), an essential activator of the Atr ... Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3 [作者：Petrova, K; Oyadomari, S; Hendershot, LM; Ron, D,期刊：EMBO journal, 页码：2862-2872 , 文章类型： Article，,卷期：2008年27-21] P58/DNAJc3 defends cells against endoplasmic reticulum ( ER) stress. Most P58 molecules are translocated into the ER lumen, and here we report selective and stable binding to misfolded proteins by P58's TPR-containing N-... Regulated release of ERdj3 from unfolded proteins by BiP [作者：Jin, Y; Awad, W; Petrova, K; Hendershot, LM,期刊：EMBO journal, 页码：2873-2882 , 文章类型： Article，,卷期：2008年27-21] DnaJ proteins often bind to unfolded substrates and recruit their Hsp70 partners. This induces a conformational change in the Hsp70 that stabilizes its binding to substrate. By some unknown mechanism, the DnaJ protein is... Human DNA polymerase iota protects cells against oxidative stress [作者：Petta, TB; Nakajima, S; Zlatanou, A; Despras, E; Couve-Privat, S; Ishchenko, A; Sarasin, A; Yasui, A; Kannouche, P,期刊：EMBO journal, 页码：2883-2895 , 文章类型： Article，,卷期：2008年27-21] Human DNA polymerase iota (poli) is a unique member of the Y-family of specialised polymerases that displays a 5'deoxyribose phosphate (dRP) lyase activity. Although poli is well conserved in higher eukaryotes, its role ... Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair [作者：Kim, HM; Narayanan, V; Mieczkowski, PA; Petes, TD; Krasilnikova, MM; Mirkin, SM; Lobachev, KS,期刊：EMBO journal, 页码：2896-2906 , 文章类型： Article，,卷期：2008年27-21] Expansion of triplex-forming GAA/TTC repeats in the first intron of FXN gene results in Friedreich's ataxia. Besides FXN, there are a number of other polymorphic GAA/TTC loci in the human genome where the size variations... Endocochlear potential depends on Cl- channels: mechanism underlying deafness in Bartter syndrome IV [作者：Rickheit, G; Maier, H; Strenzke, N; Andreescu, CE; De Zeeuw, CI; Muenscher, A; Zdebik, AA; Jentsch, TJ,期刊：EMBO journal, 页码：2907-2917 , 文章类型： Article，,卷期：2008年27-21] Human Bartter syndrome IV is an autosomal recessive disorder characterized by congenital deafness and severe renal salt and fluid loss. It is caused by mutations in BSND, which encodes barttin, a beta-subunit of ClC-Ka a... Structural basis of cargo membrane protein discrimination by the human COPII coat machinery [作者：Mancias, JD; Goldberg, J,期刊：EMBO journal, 页码：2918-2928 , 文章类型： Article，,卷期：2008年27-21] Genomic analysis shows that the increased complexity of trafficking pathways in mammalian cells involves an expansion of the number of SNARE, Rab and COP proteins. Thus, the human genome encodes four forms of Sec24, the ... Structure and function of an RNase H domain at the heart of the spliceosome [作者：Pena, V; Rozov, A; Fabrizio, P; Luhrmann, R; Wahl, MC,期刊：EMBO journal, 页码：2929-2940 , 文章类型： Article，,卷期：2008年27-21] Precursor-messenger RNA (pre-mRNA) splicing encompasses two sequential transesterification reactions in distinct active sites of the spliceosome that are transiently established by the interplay of small nuclear (sn) RNA...