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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   EDOXABAN TOSILATE Direct Factor Xa Inhibitor Prevention of Post-operative Venous Thromboembolism Treatment of Atrial Fibrillation [作者：Escolar, G; Diaz-Ricart, M,期刊：Drugs of the Future, 页码：861-872 , 文章类型： Article，,卷期：2009年34-11] Deep vein thrombosis and related complications ore important contributors to mortality and morbidity and represent a major public health concern. New orally active small molecules with powerful and reliable antithromboti... ABIRATERONE ACETATE CYP17 inhibitor Oncolytic [作者：Shah, S; Ryan, CJ,期刊：Drugs of the Future, 页码：873-880 , 文章类型： Article，,卷期：2009年34-11] Androgen deprivation therapy has been the standard of care in advanced prostate cancer for over 50 years. Although castration is initially effective, most patients eventually develop progressive disease despite low level... APTAMERS IN THE CLINIC [作者：Nimjee, SM; Sullenger, BA,期刊：Drugs of the Future, 页码：897-901 , 文章类型： Review，,卷期：2009年34-11] In 1990, an RNA molecule was designed that bound to a nucleic acid binding protein to act as a decoy, thereby preventing HIV replication. That same year, two research groups identified a high-throughput method to select ... THE MEDITERRANEAN DIET, PART III: COMPOUNDS, COMPONENTS AND CONSIDERATIONS IN RELATION TO THE RISK OF TYPE 2 DIABETES [作者：Pauwels, EKJ,期刊：Drugs of the Future, 页码：903-909 , 文章类型： Review，,卷期：2009年34-11] The dramatic increase in diabetes incidence worldwide has been attributed to various factors, including major lifestyle changes, over the post few decades. One lifestyle-related factor is the increased intake of food wit... BRIVANIB ALANINATE VEGFR/FGFR Inhibitor Oncolytic [作者：Huynh, H; Fargnoli, J,期刊：Drugs of the Future, 页码：881-895 , 文章类型： Article，,卷期：2009年34-11] Brivanib alaninate has pharmacokinetic properties suitable for once- or twice-doily oral dosing and is completely hydrolyzed to the parent drug, brivanib, in vivo. Brivanib has a favorable cytochrome P450 profile and a l... KRABBE DISEASE [作者：Sakai, N,期刊：Drugs of the Future, 页码：911-914 , 文章类型： Article，,卷期：2009年34-11] Krabbe disease is on inherited demyelinating disease caused by a deficiency of the lysosomal enzyme galactocerebrosidase (EC 3.2.1.46). The gene encoding the enzyme is GALC mopped on chromosome 14q31. Clinical phenotypes... THE ONCOLYTIC POTENTIAL OF TARGETING THE KERATINOCYTE GROWTH FACTOR (KGF)/KGF RECEPTOR PATHWAY [作者：Pento, JT,期刊：Drugs of the Future, 页码：915-924 , 文章类型： Article，,卷期：2009年34-11] Growth factors and cytokines are often directly involved in cancer cell invasion and the cascade of metastatic cancer progression. These growth factors ore often produced by stromal tissue, surrounding the primary tumors...