- Bacteriophage T5 DNA Ejection under Pressure
[作者：Leforestier, A; Brasiles, S; de Frutos, M; Raspaud, E; Letellier, L; Tavares, P; Livolant, F,期刊：Journal of Molecular Biology, 页码：730-739 , 文章类型： Article，,卷期：2008年384-3]
- The transfer of the bacteriophage genome from the capsid into the host cell is a key step of the infectious process. In bacteriophage T5, DNA ejection can be triggered in vitro by simple binding of the phage to its purif...
- Thioredoxin-1 and Its Natural Inhibitor, Vitamin D-3 Up-Regulated Protein 1, Are Differentially Regulated by PPAR alpha in Human Macrophages
[作者：Billiet, L; Furman, C; Cuaz-Perolin, C; Paumelle, R; Raymondjean, M; Simmet, T; Rouis, M,期刊：Journal of Molecular Biology, 页码：564-576 , 文章类型： Article，,卷期：2008年384-3]
- Macrophage-derived reactive oxygen species contribute to the initiation and development of atherosclerosis. The cellular balance between oxidative and reductive states depends on the endogenous antioxidant capacity, with...
- Biochemical and Structural Characterization of an Intramolecular Interaction in FOXO3a and Its Binding with p53
[作者：Wang, F; Marshall, CB; Yamamoto, K; Li, GY; Plevin, MJ; You, H; Mak, TW; Ikura, M,期刊：Journal of Molecular Biology, 页码：590-603 , 文章类型： Article，,卷期：2008年384-3]
- FOXO3a, a forkhead transcription factor and member of the forkhead box class O (FOXO) subfamily, has been shown to promote the translocation of p53 to the cytoplasm, thereby inducing the mitochondria-associated apoptotic...
- Myosin Binding Protein C Positioned to Play a Key Role in Regulation of Muscle Contraction: Structure and Interactions of Domain C1
[作者：Ababou, A; Rostkova, E; Mistry, S; Le Masurier, C; Gautel, M; Pfuhl, M,期刊：Journal of Molecular Biology, 页码：615-630 , 文章类型： Article，,卷期：2008年384-3]
- Myosin binding protein C (MyBP-C) is a thick filament protein involved in the regulation of muscle contraction. Mutations in the gene for MyBP-C are the second most frequent cause of hypertrophic cardiomyopathy. MyBP-C b...
- Yeast Mpd1p Reveals the Structural Diversity of the Protein Disulfide Isomerase Family
[作者：Vitu, E; Gross, E; Greenblaft, HM; Sevier, CS; Kaiser, CA; Fass, D,期刊：Journal of Molecular Biology, 页码：631-640 , 文章类型： Article，,卷期：2008年384-3]
- Oxidoreductases belonging to the protein disulfide isomerase (PDT) family promote proper disulfide bond formation in substrate proteins in the endoplasmic reticulum. In plants and metazoans, new family members continue t...
- Restoration of Glutathione Transferase Activity By Single-site Mutation of The Yeast Prion Protein Ure2
[作者：Zhang, ZR; Bai, M; Wang, XY; Zhou, JM; Perrett, S,期刊：Journal of Molecular Biology, 页码：641-651 , 文章类型： Article，,卷期：2008年384-3]
- The yeast prion Ure2p is composed of an N-terminal prion domain, and a C-terminal globular domain, which shows similarity to glutathione transferases (GSTs) in both sequence and structure. Ure2p protects Saccharomyces ce...
- Structure of an Archaeal Homolog of the Human Protein Complex Rpp21-Rpp29 That Is a Key Core Component for the Assembly of Active Ribonuclease P
[作者：Honda, T; Kakuta, Y; Kimura, K; Saho, J; Kimura, M,期刊：Journal of Molecular Biology, 页码：652-662 , 文章类型： Article，,卷期：2008年384-3]
- Ribonuclease P (RNase P) is a ribonucleoprotein complex involved in the processing of the 5'-leader sequence of precursor tRNA. Human RNase P protein subunits Rpp21 and Rpp29, which bind to each other, with catalytic RNA...
- Crystal Structure of the Novel Complex Formed between Zinc alpha 2-Glycoprotein (ZAG) and Prolactin-Inducible Protein (PIP) from Human Seminal Plasma
[作者：Hassan, MI; Bilgrami, S; Kumar, V; Singh, N; Yadav, S; Kaur, P; Singh, TP,期刊：Journal of Molecular Biology, 页码：663-672 , 文章类型： Article，,卷期：2008年384-3]
- This is the first r eport on the formation of a complex between zinc alpha 2-glycoprotein (ZAG) and prolactin-inducible protein (PIP). The complex was purified from human seminal plasma and crystallized using 20% polyeth...
- Targeting the X-Linked Inhibitor of Apoptosis Protein through 4-Substituted Azabicyclo[5.3.0]alkane Smac Mimetics. Structure, Activity, and Recognition Principles
[作者：Mastrangelo, E; Cossu, F; Milani, M; Sorrentino, G; Lecis, D; Delia, D; Manzoni, L; Drago, C; Seneci, P; Scolastico, C; Rizzo, V; Bolognesi, M,期刊：Journal of Molecular Biology, 页码：673-689 , 文章类型： Article，,卷期：2008年384-3]
- The X-linked inhibitor of apoptosis protein (XIAP) is overexpressed in several malignant cells where it prevents apoptosis by binding to, and blocking, the activation of caspase-3,-7, and -9. Human XIAP (479 residues) is...
- Structural Basis of the Role of the NikA Ribbon-Helix-Helix Domain in Initiating Bacterial Conjugation
[作者：Yoshida, H; Furuyal, N; Lin, YJ; Guntert, P; Komano, T; Kainosho, M,期刊：Journal of Molecular Biology, 页码：690-701 , 文章类型： Article，,卷期：2008年384-3]
- Conjugation is a fundamental process for the rapid evolution of bacteria, enabling them, for example, to adapt to various environmental conditions or to acquire multi-drug resistance. NikA is one of the relaxosomal prote...
- Thermodynamics and Folding Pathway of Tetraloop Receptor-Mediated RNA Helical Packing
[作者：Meulen, KAV; Davis, JH; Foster, TR; Record, MT; Butcher, SE,期刊：Journal of Molecular Biology, 页码：702-717 , 文章类型： Article，,卷期：2008年384-3]
- Little is known about the thermodynamic forces that drive the folding pathways of higher-order RNA structure. In this study, we employ calorimetric [isothermal titration calorimetry (ITC) and differential scanning calori...
- The Binding of Thioflavin T and Its Neutral Analog BTA-1 to Protofibrils of the Alzheimer's Disease A beta(16-22) Peptide Probed by Molecular Dynamics Simulations
[作者：Wu, C; Wang, ZX; Lei, HX; Duan, Y; Bowers, MT; Shea, JE,期刊：Journal of Molecular Biology, 页码：718-729 , 文章类型： Article，,卷期：2008年384-3]
- Thioflavin T (ThT) is a fluorescent dye commonly used to stain amyloid plaques, but the binding sites of this dye onto fibrils are poorly characterized. We present molecular dynamics simulations of the binding of ThT and...
|