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  • Ubiquitin-mediated proteolysis of HuR by heat shock
    [作者:Abdelmohsen, K; Srikantan, S; Yang, XL; Lal, A; Kim, HH; Kuwano, Y; Galban, S; Becker, KG; Kamara, D; de Cabo, R; Gorospe, M,期刊:EMBO journal, 页码:1271-1282 , 文章类型: Article,,卷期:2009年28-9]
  • The RNA-binding protein HuR regulates the stability and translation of numerous mRNAs encoding stress-response and proliferative proteins. Although its post-transcriptional influence has been linked primarily to its cyto...
  • ER stress protects from retinal degeneration
    [作者:Mendes, CS; Levet, C; Chatelain, G; Dourlen, P; Fouillet, A; Dichtel-Danjoy, ML; Gambis, A; Ryoo, HD; Steller, H; Mollereau, B,期刊:EMBO journal, 页码:1296-1307 , 文章类型: Article,,卷期:2009年28-9]
  • The unfolded protein response (UPR) is a specific cellular process that allows the cell to cope with the overload of unfolded/misfolded proteins in the endoplasmic reticulum (ER). ER stress is commonly associated with de...
  • The structural basis for peptide selection by the transport receptor OppA
    [作者:Berntsson, RPA; Doeven, MK; Fusetti, F; Duurkens, RH; Sengupta, D; Marrink, SJ; Thunnissen, AMWH; Poolman, B; Slotboom, DJ,期刊:EMBO journal, 页码:1332-1340 , 文章类型: Article,,卷期:2009年28-9]
  • Oligopeptide-binding protein A (OppA) from Lactococcus lactis binds peptides of an exceptionally wide range of lengths (4-35 residues), with no apparent sequence preference. Here, we present the crystal structures of Opp...
  • Bend into shape
    [作者:de Boer, PAJ,期刊:EMBO journal, 页码:1193-1194 , 文章类型: Article,,卷期:2009年28-9]
  • Bacteria come in a variety of shapes, as most species elaborate on the 'default' sphere to resemble ovoids, rods, bend rods, spirals, branched filaments or other more complicated forms. How cells that are under considera...