- Pharmacological Prevention and Treatment in Clinical At-Risk States for Psychosis
[作者:Ruhrmann, S; Klosterkotter, J; Bodatsch, M; Bechdolf, A; Schimmelmann, BG; Nikolaides, A; Hilboll, D; Schultze-Lutter, F,期刊:Current Pharmaceutical Design, 页码:550-557 , 文章类型: Review,,卷期:2012年18-4]
- Over the last couple of decades, the treatment of psychoses has much advanced; yet, despite all progress, the individual and societal burden associated with psychosis and particularly schizophrenia has largely remained u...
- Neuroprotective Effects of Low-dose Lithium in Individuals at Ultra-high Risk for Psychosis. A Longitudinal MRI/MRS Study
[作者:Berger, GE; Wood, SJ; Ross, M; Hamer, CA; Wellard, RM; Pell, G; Phillips, L; Nelson, B; Amminger, GP; Yung, AR; Jackson, G; Velakoulis, D; Pantelis, C; Manji, H; McGorry, PD,期刊:Current Pharmaceutical Design, 页码:570-575 , 文章类型: Review,,卷期:2012年18-4]
- Objectives: To investigate if low-dose lithium may counteract the microstructural and metabolic brain changes proposed to occur in individuals at ultra-high risk (UHR) for psychosis.Methods: Hippocampal T2 relaxation tim...
- Polyunsaturated Fatty Acids in Emerging Psychosis
[作者:Mossaheb, N; Schloegelhofer, M; Schaefer, MR; Fusar-Poli, P; Smesny, S; McGorry, P; Berger, G; Amminger, GP,期刊:Current Pharmaceutical Design, 页码:576-591 , 文章类型: Review,,卷期:2012年18-4]
- The role of polyunsaturated fatty acids and their metabolites for the cause and treatment of psychotic disorders are widely discussed. The efficacy as an augmenting agent in chronic schizophrenia seems to be small or not...
- The Ultra High Risk Approach to Define Psychosis Risk
[作者:Yung, AR; Fusar-Poli, P; Nelson, B,期刊:Current Pharmaceutical Design, 页码:346-350 , 文章类型: Review,,卷期:2012年18-4]
- Although prodromal symptoms of psychosis have long been recognized, the clinical management of psychotic disorders conventionally begins at the first episode of frank psychosis, and, until recently, the period immediatel...
- Basic Symptoms and the Prediction of First-Episode Psychosis
[作者:Schultze-Lutter, F; Ruhrmann, S; Fusar-Poli, P; Bechdolf, A; Schimmelmann, BG; Klosterkotter, J,期刊:Current Pharmaceutical Design, 页码:351-357 , 文章类型: Review,,卷期:2012年18-4]
- Recent focus on early detection and intervention in psychosis has renewed interest in subtle psychopathology beyond positive and negative symptoms. Such self-experienced sub-clinical disturbances are described in detail ...
- Rationale and First Results of Developing At-Risk (Prodromal) Criteria for Bipolar Disorder
[作者:Bechdolf, A; Ratheesh, A; Wood, SJ; Tecic, T; Conus, P; Nelson, B; Cotton, SM; Chanen, AM; Amminger, GP; Ruhrmann, S; Schultze-Lutter, F; Klosterkotter, J; Polij, PF; Yung, AR; Berk, M; McGorry, PD,期刊:Current Pharmaceutical Design, 页码:358-375 , 文章类型: Review,,卷期:2012年18-4]
- Bipolar affective disorder (BD) is a severe, recurrent and disabling disorder with devastating consequences for individuals, families and society. Although these hazards and costs provide a compelling rationale for devel...
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