- A novel human fibronectin cryptic sequence unmasked by the insertion of the angiogenesis-associated extra type III domain B
[作者:Balza, E; Sassi, F; Ventura, E; Parodi, A; Fossati, S; Blalock, W; Carnemolla, B; Castellani, P; Zardi, L; Borsi, L,期刊:International Journal of Cancer, 页码:751-758 , 文章类型: Article,,卷期:2009年125-4]
- The angiogenesis-associated extra-domain B (EDB) of fibronectin (FN) is a complete type III repeat of 91 amino acids. Its expression is modulated by the alternative splicing pattern of the FN premRNA. FN containing the E...
- Accumulation of lipid peroxidation-derived DNA lesions in iron-overloaded thalassemic mouse livers: Comparison with levels in the lymphocytes of thalassemia patients
[作者:Meerang, M; Nair, J; Sirankapracha, P; Thephinlap, C; Srichairatanakool, S; Arab, K; Kalpravidh, R; Vadolas, J; Fucharoen, S; Bartsch, H,期刊:International Journal of Cancer, 页码:759-766 , 文章类型: Article,,卷期:2009年125-4]
- In thalassemia patients, iron overload can stimulate lipid peroxidation (LPO), thereby generating miscoding DNA adducts. Adducted DNA was measured in the lymphocytes of beta-Thal/Hb E patients and healthy controls and in...
- The PTEN regulator DJ-1 is associated with hTERT expression in clear cell renal cell carcinoma
[作者:Sitaram, RT; Cairney, CJ; Grabowski, P; Keith, WN; Hallberg, B; Ljungberg, B; Roos, G,期刊:International Journal of Cancer, 页码:783-790 , 文章类型: Article,,卷期:2009年125-4]
- DJ-1 is its a novel regulator of the tumor suppressor PTEN with stimulatory effects on PI3K-AKT/PKB signaling, one possible target of which is cMyc. The catalytic unit of the telomerase complex, hTERT, can be activated a...
- Roles of clusterin in progression, chemoresistance and metastasis of human ovarian cancer
[作者:Wei, L; Xue, T; Wang, J; Chen, BL; Lei, YF; Huang, YH; Wang, HY; Xin, XY,期刊:International Journal of Cancer, 页码:791-806 , 文章类型: Article,,卷期:2009年125-4]
- Clusterin (CLU) is a multivalent glycoprotein with ubiquitous tissue distribution. To address the possible differential functional roles assumed by different isoforms of CLU in the progression of human ovarian cancer, we...
- Aryl hydrocarbon receptor activation and overexpression upregulated fibroblast growth factor-9 in human lung adenocarcinomas
[作者:Wang, CK; Hang, H; Chen, PH; Chang, JT; Kuo, YC; Ko, JL; Lin, PP,期刊:International Journal of Cancer, 页码:807-815 , 文章类型: Article,,卷期:2009年125-4]
- We had previously reported that aryl hydrocarbon receptors (AhRs) are overexpressed in lung adenocarcinomas. Benzo[a]pyrene (BaP), an AhR agonist, increased FGF-9 expression in human lung adenocarcinoma cells. Similarly,...
- Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion
[作者:Barbolina, MV; Adley, BP; Kelly, DL; Shepard, J; Fought, AJ; Scholtens, D; Penzes, P; Shea, LD; Stack, MS,期刊:International Journal of Cancer, 页码:816-825 , 文章类型: Article,,卷期:2009年125-4]
- Epithelial ovarian carcinoma (EOC) is a leading cause of death from gynecologic malignancies, due mainly to the prevalence of undetected metastatic disease. The process of cell invasion during intraperitoneal anchoring o...
- Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women
[作者:Sangrajrang, S; Sato, Y; Sakamoto, H; Ohnami, S; Laird, NM; Khuhaprema, T; Brennan, P; Boffetta, P; Yoshida, T,期刊:International Journal of Cancer, 页码:837-843 , 文章类型: Article,,卷期:2009年125-4]
- Estrogen and its metabolites are believed to play important roles in breast cancer, and its determinants include both genetic and lifestyle factors. The objective of the study is to investigate the association of breast ...
- Polymorphisms in tissue inhibitors of metalloproteinases-2 and-3 and breast cancer susceptibility and survival
[作者:Peterson, NB; Beeghly-Fadiel, A; Gao, YT; Long, JR; Cai, QY; Zheng, W,期刊:International Journal of Cancer, 页码:844-850 , 文章类型: Article,,卷期:2009年125-4]
- Tissue inhibitors of metalloproteinases (TIMPs) are endogenous inhibitors of matrix metalloproteinases which are involved in normal cellular processes and also in cancer development and progression. The purpose of this s...
- Molecular characterization of the response to chemotherapy in conventional osteosarcomas: Predictive value of HSD17B10 and IFITM2
[作者:Salas, S; Jezequel, P; Campion, L; Deville, JL; Chibon, F; Bartoli, C; Gentet, JC; Charbonnel, C; Gouraud, W; Voutsinos-Porche, B; Brouchet, A; Duffaud, F; Figarella-Branger, D; Bouvier, C,期刊:International Journal of Cancer, 页码:851-860 , 文章类型: Article,,卷期:2009年125-4]
- The therapy regimen of high-grade osteosarcoma includes chemotherapy followed by surgical resection and postoperative chemotherapy. The degree of necrosis following definitive surgery remains the only reliable prognostic...
- RB1CC1 activates the promoter and expression of RB1 in human cancer
[作者:Ikebuchi, K; Chano, T; Ochi, Y; Tameno, H; Shimada, T; Hisa, Y; Okabe, H,期刊:International Journal of Cancer, 页码:861-867 , 文章类型: Article,,卷期:2009年125-4]
- RB1-inducible coiled-coil 1 (RB1CC1, also known as FIP200) is a tumor suppressor implicated in the regulation of RB1 (retinoblastoma 1) expression. However, the molecular mechanism of RB1 regulation by RB1CC1 has not bee...
- CD4+lymphocytes modulate prostate cancer progression in mice
[作者:Poutahidis, T; Rao, VP; Olipitz, W; Taylor, CL; Jackson, EA; Levkovich, T; Lee, CW; Fox, JG; Ge, ZM; Erdman, SE,期刊:International Journal of Cancer, 页码:868-878 , 文章类型: Article,,卷期:2009年125-4]
- Chronic inflammation contributes to the development of prostate cancer in humans. Here, we shove that male Apc(Min/+) mice also develop prostate carcinoma with increasing age, mimicking that seen in humans in their 5th o...
- A high proportion of bone marrow T cells with regulatory phenotype (CD4+CD25(hi)FoxP3+) in Ewing sarcoma patients is associated with metastatic disease
[作者:Brinkrolf, P; Landmeier, S; Altvater, B; Chen, C; Pscherer, S; Rosemann, A; Ranft, A; Dirksen, U; Juergens, H; Rossig, C,期刊:International Journal of Cancer, 页码:879-886 , 文章类型: Article,,卷期:2009年125-4]
- Immunosuppressive CD4+CD25(hi)FoxP3+ T cells (T-reg cells) have been found at increased densities within the tumor microenvironment in many malignancies and interfere with protective antitumor immune responses. Osseous E...
- IL-8 induces exocytosis of arginase 1 by neutrophil polymorphonuclears in nonsmall cell lung cancer
[作者:Rotondo, R; Barisione, G; Mastracci, L; Grossi, F; Orengo, AM; Costa, R; Truini, M; Fabbi, M; Ferrini, S; Barbieri, O,期刊:International Journal of Cancer, 页码:887-893 , 文章类型: Article,,卷期:2009年125-4]
- Arginase 1 (ARG1) inhibits T-cell proliferation by degrading extracellular arginine, which results in decreased responsiveness of T cells to CD3/TCR stimulation. In humans, ARG1 is stored in inactive form within granules...
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