- SH3 binding motif 1 in influenza a virus NS1 protein is essential for P13K/Akt signaling pathway activation
[作者:Shin, YK; Li, Y; Liu, Q; Anderson, DH; Babiuk, LA; Zhou, Y,期刊:Journal of virology, 页码:12730-12739 , 文章类型: Article,,卷期:2007年81-23]
- Recent studies have demonstrated that influenza A virus infection activates the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway by binding of influenza NS1 protein to the p85 regulatory subunit of PI3K. Our pr...
- Molecular and structural bases for the antigenicity of VP2 of infectious bursal disease virus
[作者:Letzel, T; Coulibaly, F; Rey, FA; Delmas, B; Jagt, E; van Loon, AAMW; Mundt, E,期刊:Journal of virology, 页码:12827-12835 , 文章类型: Article,,卷期:2007年81-23]
- Infectious bursal disease virus (IBDV), a member of the family Birnaviridae, is responsible for a highly contagious and economically important disease causing immunosuppression in chickens. IBDV variants isolated in the ...
- Severe depletion of CD4(+) CD25(+) regulatory T cells from the intestinal lamina propria but not peripheral blood or lymph nodes during acute simian immunodeficiency virus infection
[作者:Chase, AJ; Sedaghat, AR; German, JR; Gama, L; Zink, MC; Clements, JE; Siliciano, RF,期刊:Journal of virology, 页码:12748-12757 , 文章类型: Article,,卷期:2007年81-23]
- CD4(+) CD25(+) regulatory T cells (Tregs) suppress the activation and proliferation of effector lymphocytes. In human immunodeficiency virus type 1 (HIV-1) infection, Tregs play a significant role in controlling the apop...
- Kaposi's sarcoma-associated herpesvirus encodes an ortholog of miR-155
[作者:Skalsky, RL; Samols, MA; Plaisance, KB; Boss, IW; Riva, A; Lopez, MC; Baker, HV; Renne, R,期刊:Journal of virology, 页码:12836-12845 , 文章类型: Article,,卷期:2007年81-23]
- MicroRNAs (miRNAs) are small noncoding RNAs that posttranscriptionally regulate gene expression by binding to 3'-untranslated regions (3'UTRs) of target mRNAs. Kaposi's sarcoma-associated herpesvirus (KSHV), a virus link...
- N-glycolyl GM1 ganglioside as a receptor for simian virus 40
[作者:Campanero-Rhodes, MA; Smith, A; Chai, WG; Sonnino, S; Mauri, L; Childs, RA; Zhang, YB; Ewers, H; Helenius, A; Imberty, A; Feizi, T,期刊:Journal of virology, 页码:12846-12858 , 文章类型: Article,,卷期:2007年81-23]
- Carbohydrate microarrays have emerged as powerful tools in analyses of microbe-host interactions. Using a microarray with 190 sequence-defined oligosaccharides in the form of natural glycolipids and neoglycolipids repres...
- Identification of five major and two minor genotypes of varicella-zoster virus strains: a practical two-amplicon approach used to genotype clinical isolates in Australia and New Zealand
[作者:Loparev, VN; Rubtcova, EN; Bostik, V; Govil, D; Birch, CJ; Druce, JD; Schmid, DS; Croxson, MC,期刊:Journal of virology, 页码:12758-12765 , 文章类型: Article,,卷期:2007年81-23]
- Whole genome phylogenetic analysis in this study resolved a total of five major genotypes among the 22 varicella-zoster virus (VZV) strains or isolates for which complete genomic sequences are available. Consistent with ...
- Cell-cell fusion induced by measles virus amplifies the type I interferon response
[作者:Herschke, F; Plumet, S; Duhen, T; Azocar, O; Druelle, J; Laine, D; Wild, TF; Rabourdin-Combe, C; Gerlier, D; Valentin, H,期刊:Journal of virology, 页码:12859-12871 , 文章类型: Article,,卷期:2007年81-23]
- Measles virus (MeV) infection is characterized by the formation of multinuclear giant cells (MGC). We report that beta interferon (IFN-beta) production is amplified in vitro by the formation of virus-induced MGC derived ...
- Epitope determinants of a chimpanzee dengue virus type 4 (DENV-4) -neutralizing antibody and protection against DENV-4 challenge in mice and rhesus monkeys by passively transferred humanized antibody
[作者:Lai, CJ; Goncalvez, AP; Men, R; Wernly, C; Donau, O; Engle, RE; Purcell, RH,期刊:Journal of virology, 页码:12766-12774 , 文章类型: Article,,卷期:2007年81-23]
- The chimpanzee monoclonal antibody (MAb) 5H2 is specific for dengue virus type 4 (DENV-4) and neutralizes the virus at a high titer in vitro. The epitope detected by the antibody was mapped by sequencing neutralization e...
- Virp1 is a host protein with a major role in Potato Spindle Tuber Viroid infection in Nicotiana plants
[作者:Kalantidis, K; Denti, MA; Tzortzakaki, S; Marinou, E; Tabler, M; Tsagris, M,期刊:Journal of virology, 页码:12872-12880 , 文章类型: Article,,卷期:2007年81-23]
- Viroids are small, circular, single-stranded RNA molecules that, while not coding for any protein, cause several plant diseases. Viroids rely for their infectious cycle on host proteins, most of which are likely to be in...
- HC-Pro protein of Potato Virus Y can interact with three Arabidopsis 20S proteasome Subunits in planta
[作者:Jin, YS; Ma, DY; Dong, JL; Jin, JC; Li, DF; Deng, CW; Wang, T,期刊:Journal of virology, 页码:12881-12888 , 文章类型: Article,,卷期:2007年81-23]
- The multifunctional protein helper component proteinase (HC-Pro) is thought to interfere with the activity of the 20S proteasome; however, no sites of interaction have been identified for either protein. Here, we first s...
- Human immunodeficiency virus-specific CD8(+) T-Cell activity is detectable from birth in the majority of in utero-infected infants
[作者:Thobakgale, CF; Ramduth, D; Reddy, S; Mkhwanazi, N; de Pierres, C; Moodley, E; Mphatswe, W; Blanckenberg, N; Cengimbo, A; Prendergast, A; Tudor-Williams, G; Dong, K; Jeena, P; Kindra, G; Bobat, R; Coovadia, H; Kiepiela, P; Walker, BD; Goulder, PJR,期刊:Journal of virology, 页码:12775-12784 , 文章类型: Article,,卷期:2007年81-23]
- Human immunodeficiency virus (HIV)-infected infants in sub-Saharan Africa typically progress to AIDS or death by 2 years of life in the absence of antiretroviral therapy. This rapid progression to HIV disease has been re...
- Orally administered amyloidophilic compound is effective in prolonging the incubation periods of animals cerebrally infected with prion diseases in a prion strain-dependent manner
[作者:Kawasaki, Y; Kawagoe, K; Chen, CJ; Teruya, K; Sakasegawa, Y; Doh-Ura, K,期刊:Journal of virology, 页码:12889-12898 , 文章类型: Article,,卷期:2007年81-23]
- The establishment of effective therapeutic interventions for prion diseases is necessary. We report on a newly developed amyloidophilic compound that displays therapeutic efficacy when administered orally. This compound ...
- Identification of CD46 binding sites within the adenovirus serotype 35 fiber knob
[作者:Wang, HJ; Liaw, YC; Stone, D; Kalyuzhniy, O; Amiraslanov, I; Tuve, S; Verlinde, CLMJ; Shayakhmetov, D; Stehle, T; Roffler, S; Lieber, A,期刊:Journal of virology, 页码:12785-12792 , 文章类型: Article,,卷期:2007年81-23]
- Species B human adenoviruses (Ads) are often associated with fatal illnesses in immunocompromised individuals. Recently, species B Ads, most of which use the ubiquitously expressed complement regulatory protein CD46 as a...
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