- Lurasidone hydrochloride
[作者:Cole, P; Serradell, N; Rosa, E; Bolos, J,期刊:Drugs of the Future, 页码:316-322 , 文章类型: Article,,卷期:2008年33-4]
Despite important innovations in the pharmacotherapy of schizophrenia in the last few decades, most notably the introduction of a number of dual-acting dopamine D2/5-HT2A antagonists, there remains a need for more eff...
- Monoclonal antibodies in oncological malignancies: current status and future directions
[作者:Harding, TA; Gallati, C; Horlacher, M; Becker, A; Mousa, SA,期刊:Drugs of the Future, 页码:361-369 , 文章类型: Review,,卷期:2008年33-4]
Recently, extensive research has been done in the area of bio-oncology. Bio-oncology focuses on four targets in particular: angiogenesis, signal transduction, B-cell biology and apoptosis. Monoclonal antibodies (mAbs)...
- Therapeutic targets for chronic obstructive pulmonary disease (COPD)
[作者:Sorbera, LA; Bozzo, J; Dulsat, C; Serradell, N; Rosa, E,期刊:Drugs of the Future, 页码:371-U4 , 文章类型: Article,,卷期:2008年33-4]
Chronic obstructive pulmonary disease (COPD) is a common, chronic inflammatory lung disease associated with progressive airflow obstruction. It has become apparent that, unlike asthma, antiinflammatory therapies are i...
- Apixaban
[作者:Bates, SM; Weitz, JI,期刊:Drugs of the Future, 页码:293-301 , 文章类型: Article,,卷期:2008年33-4]
Currently available anticoagulants include heparin, low-molecular-weight heparin, fondaparinux and warfarin. Despite advances, currently available agents have limitations that have provided the impetus for the develop...
- Ceftaroline fosamil
[作者:Wang, Y; Mealy, N,期刊:Drugs of the Future, 页码:302-309 , 文章类型: Article,,卷期:2008年33-4]
Ceftaroline fosamil (PPI-0903, TAK-599) is a novel N-phosphono prodrug of PPI-0903M (ceftaroline, T-91825), a broad-spectrum cephalosporin antibiotic with potent activity against methicillin-resistant Staphylococcus a...
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