- Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction
[作者:Pushpakom, SP; Liptrott, NJ; Rodriguez-Novoa, S; Labarga, P; Soriano, V; Albalater, M; Hopper-Borge, E; Bonora, S; Di Perri, G; Back, DJ; Khoo, S; Pirmohamed, M; Owen, A,期刊:Journal of Infectious Diseases, 页码:145-153 , 文章类型: Article,,卷期:2011年204-1]
- Background. Tenofovir (TFV) causes kidney tubular dysfunction (KTD) in some patients, but the mechanism is poorly understood. Genetic variants in TFV transporters are implicated; we explored whether ABCC10 transports TFV...
- Endogenous IL-13 Plays a Crucial Role in Liver Granuloma Maturation During Leishmania donovani Infection, Independent of IL-4R alpha-Responsive Macrophages and Neutrophils
[作者:McFarlane, E; Carter, KC; McKenzie, AN; Kaye, PM; Brombacher, F; Alexander, J,期刊:Journal of Infectious Diseases, 页码:36-43 , 文章类型: Article,,卷期:2011年204-1]
- Previous studies comparing interleukin 4 receptor alpha (IL-4R alpha)(-/-) and interleukin 4 (IL-4)(-/-) BALB/c mice have indicated that interleukin 13 (IL-13), whose receptor shares the IL-4R alpha subunit with IL-4, pl...
- Invasion of Erythrocytes by Francisella tularensis
[作者:Horzempa, J; O'Dee, DM; Stolz, DB; Franks, JM; Clay, D; Nau, GJ,期刊:Journal of Infectious Diseases, 页码:51-59 , 文章类型: Article,,卷期:2011年204-1]
- Francisella tularensis is the causative agent of tularemia and is classified as a category A biodefense agent by the Centers for Disease Control and Prevention because of its highly infectious nature. F. tularensis infec...
- Decorin Binding by DbpA and B of Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi Sensu Stricto
[作者:Salo, J; Loimaranta, V; Lahdenne, P; Viljanen, MK; Hytonen, J,期刊:Journal of Infectious Diseases, 页码:65-73 , 文章类型: Article,,卷期:2011年204-1]
- Background. Decorin adherence is crucial in the pathogenesis of Lyme borreliosis. Decorin-binding proteins (Dbp) A and B are the adhesins that mediate this interaction. DbpA and B of Borrelia garinii, Borrelia afzelii, a...
- An Experimental Mouse Model to Establish Tropheryma whipplei as a Diarrheal Agent
[作者:Al Moussawi, K; Malou, N; Mege, JL; Raoult, D; Desnues, B,期刊:Journal of Infectious Diseases, 页码:44-50 , 文章类型: Article,,卷期:2011年204-1]
- Tropheryma whipplei has long been considered as a rare bacterium causing a rare disease, Whipple's disease. However, recent advances now suggest that T. whipplei is a ubiquitous environmental bacterium that may cause gas...
- Prevention of Infection by a Granulocyte-Macrophage Colony-Stimulating Factor Co-Expressing DNA/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine
[作者:Lai, LL; Kwa, S; Kozlowski, PA; Montefiori, DC; Ferrari, G; Johnson, WE; Hirsch, V; Villinger, F; Chennareddi, L; Earl, PL; Moss, B; Amara, RR; Robinson, HL,期刊:Journal of Infectious Diseases, 页码:164-173 , 文章类型: Article,,卷期:2011年204-1]
- A simian immunodeficiency virus (SIV) vaccine coexpressing granulocyte-macrophage colony stimulating factor (GM-CSF) prevented infection in 71% of macaques that received 12 rectal challenges. The SIVsmE660 challenge had ...
- Relationship Between Residual Plasma Viremia and the Size of HIV Proviral DNA Reservoirs in Infected Individuals Receiving Effective Antiretroviral Therapy
[作者:Chun, TW; Murray, D; Justement, JS; Hallahan, CW; Moir, S; Kovacs, C; Fauci, AS,期刊:Journal of Infectious Diseases, 页码:135-138 , 文章类型: Article,,卷期:2011年204-1]
- Residual plasma viremia (<50 copies/mL) persists in certain human immunodeficiency virus (HIV)-infected individuals receiving antiretroviral therapy (ART); however, the relationship between the degree of residual plasma ...
- Antibodies to Plasmodium falciparum Antigens Predict a Higher Risk of Malaria But Protection From Symptoms Once Parasitemic
[作者:Greenhouse, B; Ho, B; Hubbard, A; Njama-Meya, D; Narum, DL; Lanar, DE; Dutta, S; Rosenthal, PJ; Dorsey, G; John, CC,期刊:Journal of Infectious Diseases, 页码:19-26 , 文章类型: Article,,卷期:2011年204-1]
- Background. Associations between antibody responses to Plasmodium falciparum antigens and protection against symptomatic malaria have been difficult to ascertain, in part because antibodies are potential markers of both ...
- Progressive Multifocal Leukoencephalopathy (PML) Development Is Associated With Mutations in JC Virus Capsid Protein VP1 That Change Its Receptor Specificity
[作者:Gorelik, L; Reid, C; Testa, M; Brickelmaier, M; Bossolasco, S; Pazzi, A; Bestetti, A; Carmillo, P; Wilson, E; McAuliffe, M; Tonkin, C; Carulli, JP; Lugovskoy, A; Lazzarin, A; Sunyaev, S; Simon, K; Cinque, P,期刊:Journal of Infectious Diseases, 页码:103-114 , 文章类型: Article,,卷期:2011年204-1]
- Progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease caused by JC virus (JCV) infection of oligodendrocytes, may develop in patients with immune disorders following reactivation of chronic beni...
- IL28B But Not ITPA Polymorphism Is Predictive of Response to Pegylated Interferon, Ribavirin, and Telaprevir Triple Therapy in Patients With Genotype 1 Hepatitis C
[作者:Chayama, K; Hayes, CN; Abe, H; Miki, D; Ochi, H; Karino, Y; Toyota, J; Nakamura, Y; Kamatani, N; Sezaki, H; Kobayashi, M; Akuta, N; Suzuki, F; Kumada, H,期刊:Journal of Infectious Diseases, 页码:84-93 , 文章类型: Article,,卷期:2011年204-1]
- Background. Pegylated interferon, ribavirin, and telaprevir triple therapy is a new strategy expected to eradicate the hepatitis C virus (HCV) even in patients infected with difficult-to-treat genotype 1 strains, althoug...
- Safety and Immunogenicity of a Monovalent 2009 Influenza A/H1N1v Vaccine Adjuvanted With AS03A or Unadjuvanted in HIV-Infected Adults: A Randomized, Controlled Trial
[作者:Launay, O; Desaint, C; Durier, C; Loulergue, P; Duval, X; Jacomet, C; Pialoux, G; Ghosn, J; Raffi, F; Rey, D; Ajana, F; de Verdiere, NC; Reynes, J; Foubert, V; Roman, F; Devaster, JM; Delfraissy, JF; Aboulker, JP,期刊:Journal of Infectious Diseases, 页码:124-134 , 文章类型: Article,,卷期:2011年204-1]
- Background. Human immunodeficiency virus (HIV)-infected patients have decreased immune response to vaccines. Few data are available about pandemic flu vaccination in this population. Methods. We conducted a multicenter, ...
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