- Epigenetic mechanisms of regulation of Foxp3 expression
[作者：Lal, G; Bromberg, JS,期刊：Blood, 页码：3727-3735 , 文章类型： Review，,卷期：2009年114-18]
- Regulatory T cells play important roles in the control of autoimmunity and maintenance of transplantation tolerance. Foxp3, a member of the forkhead/winged-helix family of transcription factors, acts as the master regula...
- How I treat hypereosinophilic syndromes
[作者：Klion, AD,期刊：Blood, 页码：3736-3741 , 文章类型： Article，,卷期：2009年114-18]
- Hypereosinophilic syndromes (HESs) are a heterogeneous group of uncommon disorders characterized by marked peripheral eosinophilia and end organ manifestations attributable to the eosinophilia or unexplained in the clini...
- A randomized, controlled clinical trial of ketoprofen for sickle-cell disease vaso-occlusive crises in adults
[作者：Bartolucci, P; El Murr, T; Roudot-Thoraval, F; Habibi, A; Santin, A; Renaud, B; Noel, V; Michel, M; Bachir, D; Galacteros, F; Godeau, B,期刊：Blood, 页码：3742-3747 , 文章类型： Article，,卷期：2009年114-18]
- Vaso-occlusive crisis (VOC) is the primary cause of hospitalization of patients with sickle-cell disease. Treatment mainly consists of intravenous morphine, which has many dose-related side effects. Nonsteroidal antiinfl...
- Evaluation of bone marrow reticulin formation in chronic immune thrombocytopenia patients treated with romiplostim
[作者：Kuter, DJ; Mufti, GJ; Bain, BJ; Hasserjian, RP; Davis, W; Rutstein, M,期刊：Blood, 页码：3748-3756 , 文章类型： Article，,卷期：2009年114-18]
- Romiplostim is a thrombopoietin receptor agonist that increases platelet counts in patients with chronic immune thrombocytopenia (ITP). Thrombopoietin receptor agonists are reported to increase the risk for reticulin fib...
- Safety and efficacy of hematopoietic stem cell collection from mobilized peripheral blood in unrelated volunteers: 12 years of single-center experience in 3928 donors
[作者：Holig, K; Kramer, M; Kroschinsky, F; Bornhauser, M; Mengling, T; Schmidt, AH; Rutt, C; Ehninger, G,期刊：Blood, 页码：3757-3763 , 文章类型： Article，,卷期：2009年114-18]
- We present results of peripheral blood stem cell (PBSC) mobilization, collection, and follow-up from 3928 consecutive unrelated stem cell donors. Assessments were performed prospectively at baseline, leukapheresis, 1 mon...
- Outcome of congenital acute lymphoblastic leukemia treated on the Interfant-99 protocol
[作者：van der Linden, MH; Valsecchi, MG; De Lorenzo, P; Moricke, A; Janka, G; Leblanc, TM; Felice, M; Biondi, A; Campbell, M; Hann, I; Rubnitz, JE; Stary, J; Szczepanski, T; Vora, A; Ferster, A; Hovi, L; Silverman, LB; Pieters, R,期刊：Blood, 页码：3764-3768 , 文章类型： Article，,卷期：2009年114-18]
- Acute lymphoblastic leukemia (ALL) diagnosed in the first month of life (congenital ALL) is very rare. Although congenital ALL is often assumed to be fatal, no studies have been published on outcome except for case repor...
- Prognostically relevant breakdown of 123 patients with systemic mastocytosis associated with other myeloid malignancies
[作者：Pardanani, A; Lim, KH; Lasho, TL; Finke, C; McClure, RF; Li, CY; Tefferi, A,期刊：Blood, 页码：3769-3772 , 文章类型： Article，,卷期：2009年114-18]
- The prognostic heterogeneity of the World Health Organization category of "systemic mastocytosis with associated clonal hematologic nonmast cell lineage disease" (SM-AHNMD) has not been systematically validated by primar...
- On the adaptation of endosteal stem cell niche function in response to stress
[作者：Jiang, Y; Bonig, H; Ulyanova, T; Chang, K; Papayannopoulou, T,期刊：Blood, 页码：3773-3782 , 文章类型： Article，,卷期：2009年114-18]
- Although the influence of microenvironmental "niche" on the function of a variety of stem cells is undisputed, the details of hematopoietic stem cell/niche interactions at the cellular and molecular level have sparked a ...
- Kinetics of normal hematopoietic stem and progenitor cells in a Notch1-induced leukemia model
[作者：Hu, XX; Shen, HM; Tian, C; Yu, H; Zheng, GG; XuFeng, R; Ju, ZY; Xu, J; Wang, JM; Cheng, T,期刊：Blood, 页码：3783-3792 , 文章类型： Article，,卷期：2009年114-18]
- The predominant outgrowth of malignant cells over their normal counterparts in a given tissue is a shared feature for all types of cancer. However, the impact of a cancer environment on normal tissue stem and progenitor ...
- Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia
[作者：Zhou, Q; Bucher, C; Munger, ME; Highfill, SL; Tolar, J; Munn, DH; Levine, BL; Riddle, M; June, CH; Vallera, DA; Weigel, BJ; Blazar, BR,期刊：Blood, 页码：3793-3802 , 文章类型： Article，,卷期：2009年114-18]
- Tumor-induced immune suppression can permit tumor cells to escape host immune resistance. To elucidate host factors contributing to the poor response of adoptively transferred tumor-reactive cytotoxic T lymphocytes (CTLs...
- Obesity accelerates thymic aging
[作者：Yang, H; Youm, YH; Vandanmagsar, B; Rood, J; Kumar, KG; Butler, AA; Dixit, VD,期刊：Blood, 页码：3803-3812 , 文章类型： Article，,卷期：2009年114-18]
- As the expanding obese population grows older, their successful immunologic aging will be critical to enhancing the health span. Obesity increases risk of infections and cancer, suggesting adverse effects on immune surve...
- Reciprocal role of GATA-1 and vitamin D receptor in human myeloid dendritic cell differentiation
[作者：Gobel, F; Taschner, S; Jurkin, J; Konradi, S; Vaculik, C; Richter, S; Kneidinger, D; Muhlbacher, C; Bieglmayer, C; Elbe-Burger, A; Strobl, H,期刊：Blood, 页码：3813-3821 , 文章类型： Article，,卷期：2009年114-18]
- Two major pathways of human myeloid dendritic cell (DC) subset differentiation have previously been delineated. Langerhans cells (LCs) reside in epithelia in the steady state, whereas monocytes can provide dendritic cell...
- The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia
[作者：Brunetta, E; Fogli, M; Varchetta, S; Bozzo, L; Hudspeth, KL; Marcenaro, E; Moretta, A; Mavilio, D,期刊：Blood, 页码：3822-3830 , 文章类型： Article，,卷期：2009年114-18]
- HIV-1 has developed several strategies to evade natural killer (NK)-cell antiviral functions. One of these mechanisms is the HIV-1-induced expansion of highly dysfunctional NK-cell subsets. Here, we analyze a large cohor...
- Harnessing the physiology of lymphopenia to support adoptive immunotherapy in lymphoreplete hosts
[作者：Cui, YZ; Zhang, H; Meadors, J; Poon, R; Guimond, M; Mackall, CL,期刊：Blood, 页码：3831-3840 , 文章类型： Article，,卷期：2009年114-18]
- Lymphopenia enhances the effectiveness of adoptive immunotherapy by facilitating expansion of transferred T cells but also limits the T-cell repertoire available to mediate immune responses and, in humans, is associated ...
- Potent HIV-specific responses are enriched in a unique subset of CD8(+) T cells that coexpresses CD4 on its surface
[作者：Zloza, A; Schenkel, JM; Tenorio, AR; Martinson, JA; Jeziorczak, PM; Al-Harthi, L,期刊：Blood, 页码：3841-3853 , 文章类型： Article，,卷期：2009年114-18]
- In humans, approximately 3% of peripheral CD8(+) T cells coexpress CD4 dimly on their surface and hence are designated as CD4(dim)CD8(bright) T cells. We evaluated the contribution of this CD4(dim)CD8(bright) T-cell popu...
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