- JAWS coordinates chondrogenesis and synovial joint positioning
[作者:Sohaskey, ML; Yu, J; Diaz, MA; Plaas, AH; Harland, RM,期刊:Development, 页码:2215-2220 , 文章类型: Article,,卷期:2008年135-13]
- Properly positioned synovial joints are crucial to coordinated skeletal movement. Despite their importance for skeletal development and function, the molecular mechanisms that underlie joint positioning are not well unde...
- Sonic hedgehog signalling from foregut endoderm patterns the avian nasal capsule
[作者:Benouaiche, L; Gitton, Y; Vincent, C; Couly, G; Levi, G,期刊:Development, 页码:2221-2225 , 文章类型: Article,,卷期:2008年135-13]
- Morphogenesis of the facial skeleton depends on inductive interactions between cephalic neural crest cells and cephalic epithelia, including the foregut endoderm. We show that Shh expression in the most rostral zone of t...
- Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans
[作者:Patel, DS; Fang, LL; Svy, DK; Ruvkun, G; Li, WQ,期刊:Development, 页码:2239-2249 , 文章类型: Article,,卷期:2008年135-13]
- In C. elegans, steroid hormones function in conjunction with insulin/IGF-1-like signaling in promoting reproductive development over entry into the diapausal dauer stage. The NCR-1 and -2 (NPC1-related) intracellular cho...
- mls-2 and vab-3 control glia development, hlh-17/Olig expression and glia-dependent neurite extension in C-elegans
[作者:Yoshimura, S; Murray, JI; Lu, Y; Waterston, RH; Shaham, S,期刊:Development, 页码:2263-2275 , 文章类型: Article,,卷期:2008年135-13]
- Glia are essential components of nervous systems. However, genetic programs promoting glia development and regulating glia-neuron interactions have not been extensively explored. Here we describe transcriptional programs...
- Localised axial progenitor cell populations in the avian tail bud are not committed to a posterior Hox identity
[作者:McGrew, MJ; Sherman, A; Lillico, SG; Ellard, FM; Radcliffe, PA; Gilhooley, HJ; Mitrophanous, KA; Cambray, N; Wilson, V; Sang, H,期刊:Development, 页码:2289-2299 , 文章类型: Article,,卷期:2008年135-13]
- The outgrowth of the vertebrate tail is thought to involve the proliferation of regionalised stem/progenitor cell populations formed during gastrulation. To follow these populations over extended periods, we used cells f...
- beta-Catenin has sequential roles in the survival and specification of ventral dermis
[作者:Ohtola, J; Myers, J; Akhtar-Zaidi, B; Zuzindlak, D; Sandesara, P; Yeh, K; Mackem, S; Atit, R,期刊:Development, 页码:2321-2329 , 文章类型: Article,,卷期:2008年135-13]
- The dermis promotes the development and maintains the functional components of skin, such as hair follicles, sweat glands, nerves and blood vessels. The dermis is also crucial for wound healing and homeostasis of the ski...
- LKB1 in endothelial cells is required for angiogenesis and TGF beta-mediated vascular smooth muscle cell recruitment
[作者:Londesborough, A; Vaahtomeri, K; Tiainen, M; Katajisto, P; Ekman, N; Vallenius, T; Makela, TP,期刊:Development, 页码:2331-2338 , 文章类型: Article,,卷期:2008年135-13]
- Inactivation of the tumor suppressor kinase Lkb1 in mice leads to vascular defects and midgestational lethality at embryonic day 9-11 (E9-E11). Here, we have used conditional targeting to investigate the defects underlyi...
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