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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共8条记录   Human neural stem cells transduced with IFN-beta and cytosine deaminase genes intensify bystander effect in experimental glioma [作者：Ito, S; Natsume, A; Shimato, S; Ohno, M; Kato, T; Chansakul, P; Wakabayashi, T; Kim, SU,期刊：Cancer gene therapy, 页码：299-306 , 文章类型： Article，,卷期：2010年17-5] Previously, we have shown that the genetically modified human neural stem cells (NSCs) show remarkable migratory and tumor-tropic capability to track down brain tumor cells and deliver therapeutic agents with significant... CUG2, a novel oncogene confers reoviral replication through Ras and p38 signaling pathway [作者：Park, EH; Park, EH; Cho, IR; Srisuttee, R; Min, HJ; Oh, MJ; Jeong, YJ; Jhun, BH; Johnston, RN; Lee, S; Koh, SS; Chung, YH,期刊：Cancer gene therapy, 页码：307-314 , 文章类型： Article，,卷期：2010年17-5] As we have recently found a novel oncogene, the cancer-upregulated gene 2 (CUG2), which was elevated in a variety of tumor tissues such as the ovary, liver, lung and pancreas, we examined whether reovirus could efficient... Using lentiviral vectors for efficient pancreatic cancer gene therapy [作者：Ravet, E; Lulka, H; Gross, F; Casteilla, L; Buscail, L; Cordelier, P,期刊：Cancer gene therapy, 页码：315-324 , 文章类型： Article，,卷期：2010年17-5] Pancreatic cancer (PC) remains a life-threatening disease. Efficient therapeutic gene delivery to PC-derived cells continues to present challenges. We used self-inactivated lentiviral vectors to transduce PC-derived cell... Intratumoral delivery of shRNA targeting cyclin D1 attenuates pancreatic cancer growth [作者：Deharvengt, SJ; Gunn, JR; Pickett, SB; Korc, M,期刊：Cancer gene therapy, 页码：325-333 , 文章类型： Article，,卷期：2010年17-5] The aim of this study was to assess the biological consequences of cyclin D1 silencing in pancreatic cancer cells. A replication-defective lentivirus based small hairpin RNA (shRNA) system targeting cyclin D1 caused a ma... Tumor-targeted delivery of biologically active TRAIL protein [作者：Zhang, HY; Man, JH; Liang, B; Zhou, T; Wang, CH; Li, T; Li, HY; Li, WH; Jin, BF; Zhang, PJ; Zhao, J; Pan, X; He, K; Gong, WL; Zhang, XM; Li, AL,期刊：Cancer gene therapy, 页码：334-343 , 文章类型： Article，,卷期：2010年17-5] The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a potent inducer of tumor cell apoptosis, but concerns of considerable liver toxicity limit its uses in human cancer therapy. Here, we show tha... Bovine herpesvirus type 1 as a novel oncolytic virus [作者：Rodrigues, R; Cuddington, B; Mossman, K,期刊：Cancer gene therapy, 页码：344-355 , 文章类型： Article，,卷期：2010年17-5] Oncolytic virotherapy is a promising avenue of cancer gene therapy. Current vectors include human viruses that have been engineered to replicate in tumor cells or nonhuman viruses that are naturally oncotropic and prefer... Genetic immunotherapy of lung cancer using conditionally replicating adenovirus and adenovirus-interferon-beta [作者：Park, MY; Kim, DR; Jung, HW; Yoon, HI; Lee, JH; Lee, CT,期刊：Cancer gene therapy, 页码：356-364 , 文章类型： Article，,卷期：2010年17-5] Genetic immunotherapy is considered an ideal treatment modality for cancer because of its systemic nature. This study was designed to develop a potent novel genetic immunotherapy by combining conditionally replicating ad... Down-regulation of HIF-1 alpha by oncolytic reovirus infection independently of VHL and p53 [作者：Cho, IR; Koh, SS; Min, HJ; Park, EH; Ratakorn, S; Jhun, BH; Jeong, SH; Yoo, YH; Youn, HD; Johnston, RN; Chung, YH,期刊：Cancer gene therapy, 页码：365-372 , 文章类型： Article，,卷期：2010年17-5] Many oncolytic viruses are currently being tested as potential cancer therapeutic agents. To be effective, these viruses must replicate and propagate efficiently through the tumor mass. However, it is possible that the h...