- Differential oncogenic potential of geographically distinct Helicobacter pylori CagA isoforms in mice
[作者：Miura, M; Ohnishi, N; Tanaka, S; Yanagiya, K; Hatakeyama, M,期刊：International Journal of Cancer, 页码：2497-2504 , 文章类型： Article，,卷期：2009年125-11]
- Infection with cagA-positive Helicobacter pylori is associated with gastric carcinoma. The cagA-encoded CagA protein is delivered into gastric epithelial cells and, upon tyrosine phosphorylation at the C-terminal EPIYA s...
- Overexpression of low-density lipoprotein receptor and lipid accumulation in intestinal polyps in Min mice
[作者：Mutoh, M; Komiya, M; Teraoka, N; Ueno, T; Takahashi, M; Kitahashi, T; Sugimura, T; Wakabayashi, K,期刊：International Journal of Cancer, 页码：2505-2510 , 文章类型： Article，,卷期：2009年125-11]
- Apc-deficient Min mice feature low expression of lipoprotein lipase (LPL), high concentration of serum triglyceride (TG), fatty change of the liver and large numbers of intestinal polyps. We have reported that induction ...
- Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1
[作者：Liu, FN; Li, XD; Wang, CY; Cai, XZ; Du, ZM; Xu, HM; Li, F,期刊：International Journal of Cancer, 页码：2511-2519 , 文章类型： Article，,卷期：2009年125-11]
- p21-activated kinase 1 (Pak1), a serine/threonine kinase, has been implicated in cytoskeletal remodelling, cell motility, apoptosis and transformation. However, the role of Pak1 in gastric cancer remains unclear. In this...
- RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells
[作者：Kim, DM; Chung, KS; Choi, SJ; Jung, YJ; Park, SK; Han, GH; Ha, JS; Song, KB; Choi, NS; Kim, HM; Won, M; Seo, YS,期刊：International Journal of Cancer, 页码：2520-2527 , 文章类型： Article，,卷期：2009年125-11]
RhoB, a tumor suppressor, has emerged as an interesting cancer target, and extensive studies aimed at understanding its role in apoptosis have been performed. In our study, we investigated the involvement of RhoB-inte...
- Annexin-A7 protects normal prostate cells and induces distinct patterns of RB-associated cytotoxicity in androgen-sensitive and -resistant prostate cancer cells
[作者：Torosyan, Y; Simakova, O; Naga, S; Mezhevaya, K; Leighton, X; Diaz, J; Huang, W; Pollard, H; Srivastava, M,期刊：International Journal of Cancer, 页码：2528-2539 , 文章类型： Article，,卷期：2009年125-11]
- The tumor suppressor role of annexin-A7 (ANXA7) was previously demonstrated by cancer susceptibility in Anxa7(+/-)-mice and by ANXA7 loss in human cancers, especially in hormone-resistant prostate tumors. To gain mechani...
- Prostaglandin E-2 promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells
[作者：Yu, L; Wu, WKK; Li, ZJ; Li, HT; Wu, YC; Cho, CH,期刊：International Journal of Cancer, 页码：2540-2546 , 文章类型： Article，,卷期：2009年125-11]
- Overexpression of cyclooxygenase-2 (COX-2) and elevation of its derivative prostaglandin E-2 (PGE(2)) are implicated in human esophageal squamous cell carcinoma. The expression of c-Myc, an oncogenic transcription factor...
- Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model
[作者：Vitali, R; Mancini, C; Cesi, V; Tanno, B; Piscitelli, M; Mancuso, M; Sesti, F; Pasquali, E; Calabretta, B; Dominici, C; Raschella, G,期刊：International Journal of Cancer, 页码：2547-2555 , 文章类型： Article，,卷期：2009年125-11]
- Stage 4 neuroblastoma (NB) is a devastating childhood cancer whose poor outcome has remained essentially unchanged in the last 20 years. Receptor tyrosine kinases have important roles in the control of proliferation, dif...
- HER3 is required for the maintenance of neuregulin-dependent and -independent attributes of malignant progression in prostate cancer cells
[作者：Soler, M; Mancini, F; Meca-Cortes, O; Sanchez-Cid, L; Rubio, N; Lopez-Fernandez, S; Lozano, JJ; Blanco, J; Fernandez, PL; Thomson, TM,期刊：International Journal of Cancer, 页码：2565-2575 , 文章类型： Article，,卷期：2009年125-11]
- HER3 (ERBB3) is a catalytically inactive pseudokinase of the HER receptor tyrosine kinase family, frequently overexpressed in prostate and other cancers. Aberrant expression and mutations of 2 other members of the family...
- Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway
[作者：Li, B; Tsao, SW; Li, YY; Wang, XH; Ling, MT; Wong, YC; He, QY; Cheung, ALM,期刊：International Journal of Cancer, 页码：2576-2585 , 文章类型： Article，,卷期：2009年125-11]
- Id-1 (inhibitor of differentiation or DNA binding) is a helix-loop-helix protein that is overexpressed in many types of cancer including esophageal squamous cell carcinoma (ESCC). We previously reported that ectopic Id-1...
- Antagonism of chemokine receptor CXCR3 inhibits osteosarcoma metastasis to lungs
[作者：Pradelli, E; Karimdjee-Soilihi, B; Michiels, JF; Ricci, JE; Millet, MA; Vandenbos, F; Sullivan, TJ; Collins, TL; Johnson, MG; Medina, JC; Kleinerman, ES; Schmid-Alliana, A; Schmid-Antomarchi, H,期刊：International Journal of Cancer, 页码：2586-2594 , 文章类型： Article，,卷期：2009年125-11]
- Metastasis continues to be the leading cause of mortality for patients with cancer. Several years ago, it became clear that chemokines and their receptors could control the tumor progress. CXCR3 has now been identified i...
- Synergistic effect of HLA class II loci and cytokine gene polymorphisms on the risk of gastric cancer in Japanese patients with Helicobacter pylori infection
[作者：Ando, T; Ishikawa, T; Kato, H; Yoshida, N; Naito, Y; Kokura, S; Yagi, N; Takagi, T; Handa, O; Kitawaki, J; Nakamura, N; Hasegawa, G; Fukui, M; Imamoto, E; Nakamura, C; Oyamada, H; Isozaki, Y; Matsumoto, N; Nagao, Y; Okita, M; Nakajima, Y; Kurokawa, M; Nukina, M; Ohta, M; Mizuno, S; Ogata, M; Obayashi, H; Park, H; Kitagawa, Y; Nakano, K; Yoshikawa, T,期刊：International Journal of Cancer, 页码：2595-2602 , 文章类型： Article，,卷期：2009年125-11]
- It has been reported that polymorphisms of human leukocyte antigen (HLA) genes and several cytokine genes are associated with an increased risk of developing gastric cancer (GC). However, the results of studies from diff...
- Association of HPV16 E6 variants with diagnostic severity in cervical cytology samples of 354 women in a US population
[作者：Zuna, RE; Moore, WE; Shanesmith, RP; Dunn, ST; Wang, SS; Schiffman, M; Blakey, GL; Teel, T,期刊：International Journal of Cancer, 页码：2609-2613 , 文章类型： Article，,卷期：2009年125-11]
- It has been suggested that DNA sequence variants of HPV16 contribute to differences in the behavior of individual cervical lesions. To address this question, we have analyzed the association of HPV16 variants with diagno...
- Peptide inhibitors of transforming growth factor-beta enhance the efficacy of antitumor immunotherapy
[作者：Llopiz, D; Dotor, J; Casares, N; Bezunartea, J; Diaz-Valdes, N; Ruiz, M; Aranda, F; Berraondo, P; Prieto, J; Lasarte, JJ; Borras-Cuesta, F; Sarobe, P,期刊：International Journal of Cancer, 页码：2614-2623 , 文章类型： Article，,卷期：2009年125-11]
- Transforming growth factor-beta (TGF-beta) is a cytokine with potent immunosuppressive effects and is overexpressed in many tumors. Therefore, development of molecules able to inhibit TGF-beta is of paramount importance ...
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