- POU Homeodomain Protein Oct-1 Functions as a Sensor for Cyclic AMP
[作者：Wang, PX; Wang, QH; Sun, J; Wu, J; Li, H; Zhang, NN; Huang, YC; Su, B; Li, RK; Liu, L; Zhang, Y; Elsholtz, HP; Hu, J; Gaisano, HY; Jin, TR,期刊：Journal of Biological Chemistry, 页码：26456-26465 , 文章类型： Article，,卷期：2009年284-39]
- Cyclic AMP is a fundamentally important second messenger for numerous peptide hormones and neurotransmitters that control gene expression, cell proliferation, and metabolic homeostasis. Here we show that cAMP works with ...
- Unraveling Delta(1)-Pyrroline-5-Carboxylate-Proline Cycle in Plants by Uncoupled Expression of Proline Oxidation Enzymes
[作者：Miller, G; Honig, A; Stein, H; Suzuki, N; Mittler, R; Zilberstein, A,期刊：Journal of Biological Chemistry, 页码：26482-26492 , 文章类型： Article，,卷期：2009年284-39]
- The two-step oxidation of proline in all eukaryotes is performed at the inner mitochondrial membrane by the consecutive action of proline dehydrogenase (ProDH) that produces Delta(1)-pyrroline-5-carboxylate (P5C) and P5C...
- YB-1 Acts as a Ligand for Notch-3 Receptors and Modulates Receptor Activation
[作者：Rauen, T; Raffetseder, U; Frye, BC; Djudjaj, S; Muhlenberg, PJT; Eitner, F; Lendahl, U; Bernhagen, J; Dooley, S; Mertens, PR,期刊：Journal of Biological Chemistry, 页码：26928-26940 , 文章类型： Article，,卷期：2009年284-39]
- Y-box (YB) protein-1 is secreted by mesangial and immune cells after cytokine challenge, but extracellular functions are unknown. Here, we demonstrate that extracellular YB-1 associates with outer cell membrane component...
- Detailed Mechanistic Insights into HIV-1 Sensitivity to Three Generations of Fusion Inhibitors
[作者：Eggink, D; Langedijk, JPM; Bonvin, AMJJ; Deng, YQ; Lu, M; Berkhout, B; Sanders, RW,期刊：Journal of Biological Chemistry, 页码：26941-26950 , 文章类型： Article，,卷期：2009年284-39]
- Peptides based on the second heptad repeat (HR2) of viral class I fusion proteins are effective inhibitors of virus entry. One such fusion inhibitor has been approved for treatment of human immunodeficiency virus-1 (T20,...
- SLIMMER (FHL1B/KyoT3) Interacts with the Proapoptotic Protein Siva-1 (CD27BP) and Delays Skeletal Myoblast Apoptosis
[作者：Cottle, DL; McGrath, MJ; Wilding, BR; Cowling, BS; Kane, JM; D'Arcy, CE; Holdsworth, M; Hatzinisiriou, I; Prescott, M; Brown, S; Mitchell, CA,期刊：Journal of Biological Chemistry, 页码：26964-26977 , 文章类型： Article，,卷期：2009年284-39]
- The fhl1 gene encoding four-and-a-half LIM protein-1 (FHL1) and its spliced isoform, SLIMMER, is mutated in reducing body myopathy, X-linked myopathy with postural muscle atrophy, scapuloperoneal myopathy, and rigid spin...
- A Caenorhabditis elegans Glycolipid-binding Galectin Functions in Host Defense against Bacterial Infection
[作者：Ideo, H; Fukushima, K; Gengyo-Ando, K; Mitani, S; Dejima, K; Nomura, K; Yamashita, K,期刊：Journal of Biological Chemistry, 页码：26493-26501 , 文章类型： Article，,卷期：2009年284-39]
- Galectins are a family of beta-galactoside-binding proteins that are widely found among animal species and that regulate diverse biological phenomena. To study the biological function of glycolipid-binding galectins, we ...
- A JAK2 Interdomain Linker Relays Epo Receptor Engagement Signals to Kinase Activation
[作者：Zhao, LQ; Dong, HY; Zhang, CC; Kinch, L; Osawa, M; Iacovino, M; Grishin, NV; Kyba, M; Huang, LJS,期刊：Journal of Biological Chemistry, 页码：26988-26998 , 文章类型： Article，,卷期：2009年284-39]
- JAK2 (Janus kinase 2) is essential for cytokine receptor signaling, and several lines of evidence support a causal role of an activating JAK2 mutation in myeloproliferative disorders. JAK2 activity is autoinhibited by it...
- Targeted Inactivation of a Developmentally Regulated Neural Plectin Isoform (Plectin 1c) in Mice Leads to Reduced Motor Nerve Conduction Velocity
[作者：Fuchs, P; Zorer, M; Reipert, S; Rezniczek, GA; Propst, F; Walko, G; Fischer, I; Bauer, J; Leschnik, MW; Luscher, B; Thalhammer, JG; Lassmann, H; Wiche, G,期刊：Journal of Biological Chemistry, 页码：26502-26509 , 文章类型： Article，,卷期：2009年284-39]
- Cytolinker proteins stabilize cells mechanically, regulate cytoskeleton dynamics, and provide scaffolds for signaling molecules. For plectin, the prototype of these proteins, an unusual diversity of isoforms has been rep...
- ATP Binding to the C Terminus of the Arabidopsis thaliana Nitrate/Proton Antiporter, AtCLCa, Regulates Nitrate Transport into Plant Vacuoles
[作者：De Angeli, A; Moran, O; Wege, S; Filleur, S; Ephritikhine, G; Thomine, S; Barbier-Brygoo, H; Gambale, F,期刊：Journal of Biological Chemistry, 页码：26526-26532 , 文章类型： Article，,卷期：2009年284-39]
- Nitrate, one of the major nitrogen sources for plants, is stored in the vacuole. Nitrate accumulation within the vacuole is primarily mediated by the NO3-/H+ exchanger AtCLCa, which belongs to the chloride channel (CLC) ...
- Structural Plasticity of Malaria Dihydroorotate Dehydrogenase Allows Selective Binding of Diverse Chemical Scaffolds
[作者：Deng, XY; Gujjar, R; El Mazouni, F; Kaminsky, W; Malmquist, NA; Goldsmith, EJ; Rathod, PK; Phillips, MA,期刊：Journal of Biological Chemistry, 页码：26999-27009 , 文章类型： Article，,卷期：2009年284-39]
- Malaria remains a major global health burden and current drug therapies are compromised by resistance. Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) was validated as a new drug target through the identific...
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