- The role of microRNAs in cancer: diagnostic and prognostic biomarkers and targets of therapies
[作者：Corsini, LR; Bronte, G; Terrasi, M; Amodeo, V; Fanale, D; Fiorentino, E; Cicero, G; Bazan, V; Russo, A,期刊：Expert Opinion on Therapeutic Targets, 页码：S103-S109 , 文章类型： Review，,卷期：2012年16-4s]
- Introduction: miRNAs are noncoding RNAs that target specific mRNA with subsequent regulation of particular genes, implicated in various biological processes. In cancer, miRNAs could show a different expression from norma...
- Integration of radioembolisation into multimodal treatment of liver-dominant metastatic colorectal cancer
[作者：Cosimelli, M; Mancini, R; Carpanese, L; Sciuto, R; Pizzi, G; Pattaro, G; Maini, CL,期刊：Expert Opinion on Therapeutic Targets, 页码：S11-S16 , 文章类型： Review，,卷期：2012年16-4s]
- Introduction: Radioembolisation (selective internal radiation therapy; SIRT), as part of a continuous strategy contributed to the improvement in response rates and median survival for unresectable metastatic colorectal c...
- Current status of targeted therapies in advanced gastric cancer
[作者：De Vita, F; Giuliani, F; Silvestris, N; Rossetti, S; Pizzolorusso, A; Santabarbara, G; Galizia, G; Colucci, G; Ciardiello, F; Orditura, M,期刊：Expert Opinion on Therapeutic Targets, 页码：S29-S34 , 文章类型： Review，,卷期：2012年16-4s]
- Introduction: In metastatic gastric cancer, chemotherapy is the standard treatment because it prolongs survival when compared to best supportive care alone. However, even after the use of more effective regimens, the ove...
- Oral tyrosine kinase inhibitors in the first-line treatment of advanced non-small cell lung cancer
[作者：Gori, B; Ricciardi, S; Del Signore, E; Fulvi, A; de Marinis, F,期刊：Expert Opinion on Therapeutic Targets, 页码：S55-S60 , 文章类型： Review，,卷期：2012年16-4s]
- Introduction: In EGFR mutated advanced NSCLC, tyrosine kinase inhibitors are new valid options as first-line treatment. Gefitinib appears a valid alternative to chemotherapy as first-line therapy, in EGFR mutated elderly...
- Combined modality treatments in pancreatic cancer
[作者：Lombardi, L; Troiano, M; Silvestris, N; Nanni, L; Latiano, TP; Di Maggio, G; Cinieri, S; Di Sebastiano, P; Colucci, G; Maiello, E,期刊：Expert Opinion on Therapeutic Targets, 页码：S71-S81 , 文章类型： Review，,卷期：2012年16-4s]
- Introduction: Of all the carcinomas, pancreatic carcinoma (PC) has the highest mortality rate, with a 1- and 5-year survival rate of 25% and less than 5% respectively. This is regardless of the stage at diagnosis. Areas ...
- Poly (ADP-ribose) polymerase (PARP): rationale, preclinical and clinical evidences of its inhibition as breast cancer treatment
[作者：Orlando, L; Schiavone, P; Fedele, P; Calvani, N; Nacci, A; Cinefra, M; D'Amico, M; Mazzoni, E; Marino, A; Sponziello, F; Morelli, F; Lombardi, L; Silvestris, N; Cinieri, S,期刊：Expert Opinion on Therapeutic Targets, 页码：S83-S89 , 文章类型： Review，,卷期：2012年16-4s]
- Introduction: The chance to take advantage of genetic defects of cancer cells is a promising clinical tool in breast cancer therapy. Among the genetic aberrations, dysfunctions in DNA repair mechanisms are quite common a...
- Therapy innovation for the treatment of pancreatic neuroendocrine tumors
[作者：Riccardi, F; Rizzo, M; Festino, L; Ambrosio, F; Molino, C; Uomo, G; Carteni, G,期刊：Expert Opinion on Therapeutic Targets, 页码：S91-S102 , 文章类型： Review，,卷期：2012年16-4s]
- Introduction: Traditional therapeutic approaches for patients with advanced neuroendocrine tumors (NETs) have included treatment with somatostatin analogs, hepatic-directed therapies, interferon and cytotoxic chemotherap...
- Optimized granulocyte colony-stimulating factor prophylaxis in adult cancer patients: from biological principles to clinical guidelines
[作者：Silvestris, N; Del Re, M; Azzariti, A; Maiello, E; Lombardi, L; Cinieri, S; Guarini, A; Brunetti, AE; Delcuratolo, S; De Vita, F; Pisconti, S; Danesi, R; Colucci, G,期刊：Expert Opinion on Therapeutic Targets, 页码：S111-S117 , 文章类型： Review，,卷期：2012年16-4s]
- Introduction: Chemotherapy-induced neutropenia, the depth and length of which are correlated to the risk of febrile neutropenia (FN) and neutropenia sepsis, remains a serious problem in medical oncology. Granulocyte colo...
- Premetastatic niche: ready for new therapeutic interventions?
[作者：Zoccoli, A; Iuliani, M; Pantano, F; Imperatori, M; Intagliata, S; Vincenzi, B; Marchetti, P; Papapietro, N; Denaro, V; Tonini, G; Santini, D,期刊：Expert Opinion on Therapeutic Targets, 页码：S119-S129 , 文章类型： Review，,卷期：2012年16-4s]
- Introduction: Bone marrow-derived cells (BMDC) localize in premetastatic niche through chemokines and integrins signals and establish clusters that precede the arrival of even single metastatic tumor cell at distant site...
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