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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共8条记录   Mast cells in endometriosis: guilty or innocent bystanders? [作者：Kirchhoff, D; Kaulfuss, S; Fuhrmann, U; Maurer, M; Zollner, TM,期刊：Expert Opinion on Therapeutic Targets, 页码：237-241 , 文章类型： Editorial Material，,卷期：2012年16-3] Endometriosis (EMS) is a chronic, estrogen-dependent inflammatory disease characterized by growth of endometrial tissue outside the uterine cavity. Symptoms in EMS patients include severe pelvic pain, dysmenorrhea, dyspa... An update on targeting Hippo-YAP signaling in liver cancer [作者：Liu, AM; Xu, Z; Luk, JM,期刊：Expert Opinion on Therapeutic Targets, 页码：243-247 , 文章类型： Editorial Material，,卷期：2012年16-3] Hepatocellular carcinoma (HCC) is an aggressive malignancy with approximately half a million cases diagnosed each year. Although strategies in surgical interventions have been investigated and applied, the prognosis is s... Targeting frameshifting in the human immunodeficiency virus [作者：Brakier-Gingras, L; Charbonneau, J; Butcher, SE,期刊：Expert Opinion on Therapeutic Targets, 页码：249-258 , 文章类型： Review，,卷期：2012年16-3] Introduction: HIV-1 uses a programmed -1 ribosomal frameshift to generate Gag-Pol, the precursor of its enzymes, when its full-length mRNA is translated by the ribosomes of the infected cells. This change in the reading ... CD133 as a target for colon cancer [作者：Catalano, V; Di Franco, S; Iovino, F; Dieli, F; Stassi, G; Todaro, M,期刊：Expert Opinion on Therapeutic Targets, 页码：259-267 , 文章类型： Review，,卷期：2012年16-3] Introduction: Recent evidence based on cancer stem cell (CSC) models, is boosting the progress of translational research and providing relevant clinical implications in many tumour types, including colorectal cancer. The... Antidiabetic effects of natural plant extracts via inhibition of carbohydrate hydrolysis enzymes with emphasis on pancreatic alpha amylase [作者：Etxeberria, U; de la Garza, AL; Campion, J; Martinez, JA; Milagro, FI,期刊：Expert Opinion on Therapeutic Targets, 页码：269-297 , 文章类型： Review，,卷期：2012年16-3] Introduction: The increasing prevalence of type 2 diabetes mellitus and the negative clinical outcomes observed with the commercially available antidiabetic drugs have led to the investigation of new therapeutic approach... Kinin receptors as targets for cancer therapy [作者：Figueroa, CD; Ehrenfeld, P; Bhoola, KD,期刊：Expert Opinion on Therapeutic Targets, 页码：299-312 , 文章类型： Review，,卷期：2012年16-3] Introduction: Biological fluids of cancer patients contain increased levels of kinins. Activation of kinin B1 and B2 receptors expressed on cancer cells produce an increase in cell proliferation, migration of tumor cells... Targeting JAK2 in the therapy of myeloproliferative neoplasms [作者：Reddy, MM; Deshpande, A; Sattler, M,期刊：Expert Opinion on Therapeutic Targets, 页码：313-324 , 文章类型： Review，,卷期：2012年16-3] Introduction: Myeloproliferative neoplasms (MPNs) are a group of stem cell diseases, including polycythemia vera, essential thrombocythemia and primary myelofibrosis. Currently, there is no curative therapy for these dis... Protein kinase C beta II in diabetic complications: survey of structural, biological and computational studies [作者：Sobhia, ME; Grewal, BK; Bhat, J; Rohit, S; Punia, V,期刊：Expert Opinion on Therapeutic Targets, 页码：325-344 , 文章类型： Review，,卷期：2012年16-3] Introduction: PKC-beta II is a conventional isoform of PKC. It is overexpressed in hyperglycemic conditions and is known to trigger various diabetic complications, mainly cardiovascular complications and to a certain ext...