- Incomplete X-inactivation initiated by a hypomorphic Xist allele in the mouse
[作者:Hoki, Y; Ikeda, R; Mise, N; Sakata, Y; Ohhata, T; Sasaki, H; Abe, K; Sado, T,期刊:Development, 页码:2649-2659 , 文章类型: Article,,卷期:2011年138-13]
- X chromosome inactivation (X-inactivation) in female mammals is triggered by differential upregulation of the Xist gene on one of the two X chromosomes and subsequent coating of the X in cis with its non-coding transcrip...
- Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development
[作者:Fernandez-Miranda, G; Trakala, M; Martin, J; Escobar, B; Gonzalez, A; Ghyselinck, NB; Ortega, S; Canamero, M; de Castro, IP; Malumbres, M,期刊:Development, 页码:2661-2672 , 文章类型: Article,,卷期:2011年138-13]
- Mitosis is controlled by multiple kinases that drive cell cycle progression and prevent chromosome mis-segregation. Aurora kinase B interacts with survivin, borealin and incenp to form the chromosomal passenger complex (...
- Gpr126 is essential for peripheral nerve development and myelination in mammals
[作者:Monk, KR; Oshima, K; Jors, S; Heller, S; Talbot, WS,期刊:Development, 页码:2673-2680 , 文章类型: Article,,卷期:2011年138-13]
- In peripheral nerves, Schwann cells form the myelin sheath that insulates axons and allows rapid propagation of action potentials. Although a number of regulators of Schwann cell development are known, the signaling path...
- Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis
[作者:Haara, O; Fujimori, S; Schmidt-Ullrich, R; Hartmann, C; Thesleff, I; Mikkola, ML,期刊:Development, 页码:2681-2691 , 文章类型: Article,,卷期:2011年138-13]
- The developing submandibular salivary gland (SMG) is a well-studied model for tissue interactions and branching morphogenesis. Its development shares similar features with other ectodermal appendages such as hair and too...
- Neuroendocrine regulation of Drosophila metamorphosis requires TGF beta/Activin signaling
[作者:Gibbens, YY; Warren, JT; Gilbert, LI; O'Connor, MB,期刊:Development, 页码:2693-2703 , 文章类型: Article,,卷期:2011年138-13]
- In insects, initiation of metamorphosis requires a surge in the production of the steroid hormone 20-hydroxyecdysone from the prothoracic gland, the primary endocrine organ of juvenile larvae. Here, we show that blocking...
- Fibroblast growth factor signalling controls successive cell behaviours during mesoderm layer formation in Drosophila
[作者:Clark, IBN; Muha, V; Klingseisen, A; Leptin, M; Muller, HAJ,期刊:Development, 页码:2705-2715 , 文章类型: Article,,卷期:2011年138-13]
- Fibroblast growth factor (FGF)-dependent epithelial-mesenchymal transitions and cell migration contribute to the establishment of germ layers in vertebrates and other animals, but a comprehensive demonstration of the cel...
- Alk3 controls nephron number and androgen production via lineage-specific effects in intermediate mesoderm
[作者:Di Giovanni, V; Alday, A; Chi, LJ; Mishina, Y; Rosenblum, ND,期刊:Development, 页码:2717-2727 , 文章类型: Article,,卷期:2011年138-13]
- The mammalian kidney and male reproductive system are both derived from the intermediate mesoderm. The spatial and temporal expression of bone morphogenetic protein (BMP) 2 and BMP4 and their cognate receptor, activin li...
- The WASp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release
[作者:Rotkopf, S; Hamberg, Y; Aigaki, T; Snapper, SB; Shilo, BZ; Schejter, ED,期刊:Development, 页码:2729-2739 , 文章类型: Article,,卷期:2011年138-13]
- WASp family proteins serve as conserved regulators of branched microfilament array formation via the Arp2/3 actin polymerization machinery. We have identified a specific role during spermatogenesis for the Drosophila WAS...
- Scaling of the Bicoid morphogen gradient by a volume-dependent production rate
[作者:Cheung, D; Miles, C; Kreitman, M; Ma, J,期刊:Development, 页码:2741-2749 , 文章类型: Article,,卷期:2011年138-13]
- An important feature of development is the formation of patterns that are proportional to the overall size of the embryo. But how such proportionality, or scaling, is achieved mechanistically remains poorly understood. F...
- Evolutionary plasticity of segmentation clock networks
[作者:Krol, AJ; Roellig, D; Dequeant, ML; Tassy, O; Glynn, E; Hattem, G; Mushegian, A; Oates, AC; Pourquie, O,期刊:Development, 页码:2783-2792 , 文章类型: Article,,卷期:2011年138-13]
- The vertebral column is a conserved anatomical structure that defines the vertebrate phylum. The periodic or segmental pattern of the vertebral column is established early in development when the vertebral precursors, th...
|