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  • Nanog Regulates Primordial Germ Cell Migration Through Cxcr4b
    [作者:Sanchez-Sanchez, AV; Camp, E; Leal-Tassias, A; Atkinson, SP; Armstrong, L; Diaz-Llopis, M; Mullor, JL,期刊:Stem Cells, 页码:1457-1464 , 文章类型: Article,,卷期:2010年28-9]
  • Gonadal development in vertebrates depends on the early determination of primordial germ cells (PGCs) and their correct migration to the sites where the gonads develop. Several genes have been implicated in PGC specifica...
  • Human Embryonic Stem Cells as Models for Aneuploid Chromosomal Syndromes
    [作者:Biancotti, JC; Narwani, K; Buehler, N; Mandefro, B; Golan-Lev, T; Yanuka, O; Clark, A; Hill, D; Benvenisty, N; Lavon, N,期刊:Stem Cells, 页码:1530-1540 , 文章类型: Article,,卷期:2010年28-9]
  • Syndromes caused by chromosomal aneuploidies are widely recognized genetic disorders in humans and often lead to spontaneous miscarriage. Preimplantation genetic screening is used to detect chromosomal aneuploidies in ea...
  • Loss of Bright/ARID3a Function Promotes Developmental Plasticity
    [作者:An, GY; Miner, CA; Nixon, JC; Kincade, PW; Bryant, J; Tucker, PW; Webb, CF,期刊:Stem Cells, 页码:1560-1567 , 文章类型: Article,,卷期:2010年28-9]
  • B-cell regulator of immunoglobulin heavy chain transcription (Bright)/ARID3a, an A+T-rich interaction domain protein, was originally discovered in B lymphocyte lineage cells. However, expression patterns and high lethali...