- Concise Review: Nanoparticles and Cellular Carriers-Allies in Cancer Imaging and Cellular Gene Therapy?
[作者:Tang, C; Russell, PJ; Martiniello-Wilks, R; Rasko, JEJ; Khatri, A,期刊:Stem Cells, 页码:1686-1702 , 文章类型: Review,,卷期:2010年28-9]
- Ineffective treatment and poor patient management continue to plague the arena of clinical oncology. The crucial issues include inadequate treatment efficacy due to ineffective targeting of cancer deposits, systemic toxi...
- Nanog Regulates Primordial Germ Cell Migration Through Cxcr4b
[作者:Sanchez-Sanchez, AV; Camp, E; Leal-Tassias, A; Atkinson, SP; Armstrong, L; Diaz-Llopis, M; Mullor, JL,期刊:Stem Cells, 页码:1457-1464 , 文章类型: Article,,卷期:2010年28-9]
- Gonadal development in vertebrates depends on the early determination of primordial germ cells (PGCs) and their correct migration to the sites where the gonads develop. Several genes have been implicated in PGC specifica...
- Major Histocompatibility Complex-I Expression on Embryonic Stem Cell-Derived Vascular Progenitor Cells Is Critical for Syngeneic Transplant Survival
[作者:Ma, MC; Ding, SL; Lundqvist, A; San, H; Fang, F; Konoplyannikov, M; Berry, C; Beltran, LE; Chen, GB; Kovacic, JC; Boehm, M,期刊:Stem Cells, 页码:1465-1475 , 文章类型: Article,,卷期:2010年28-9]
- Donor-recipient cell interactions are essential for functional engraftment after nonautologous cell transplantation. During this process, transplant engraftment is characterized and defined by interactions between transp...
- Zap70 Functions to Maintain Stemness of Mouse Embryonic Stem Cells by Negatively Regulating Jak1/Stat3/c-Myc Signaling
[作者:Cha, Y; Moon, BH; Lee, MO; Ahn, HJ; Lee, HJ; Lee, KA; Fornace, AJ; Kim, KS; Cha, HJ; Park, KS,期刊:Stem Cells, 页码:1476-1486 , 文章类型: Article,,卷期:2010年28-9]
- Zeta-chain-associated protein kinase-70 (Zap70), a Syk family tyrosine kinase, has been reported to be present exclusively in normal T-cells, natural killer cells, and B cells, serving as a pivotal regulator of antigen-m...
- Retinoic Acid Synthesis Promotes Development of Neural Progenitors from Mouse Embryonic Stem Cells by Suppressing Endogenous, Wnt-Dependent Nodal Signaling
[作者:Engberg, N; Kahn, M; Petersen, DR; Hansson, M; Serup, P,期刊:Stem Cells, 页码:1498-1509 , 文章类型: Article,,卷期:2010年28-9]
- Embryonic stem (ES) cells differentiate spontaneously toward a neuroectodermal fate in serum-free, adherent monocultures. Here, we show that this spontaneous neural fate requires retinoic acid (RA) synthesis. We monitor ...
- Kruppel-Like Transcription Factor 4 Contributes to Maintenance of Telomerase Activity in Stem Cells
[作者:Wong, CW; Hou, PS; Tseng, SF; Chien, CL; Wu, KJ; Chen, HF; Ho, HN; Kyo, S; Teng, SC,期刊:Stem Cells, 页码:1510-1517 , 文章类型: Article,,卷期:2010年28-9]
- The zinc finger Kruppel-like transcription factor 4 (KLF4) has been implicated in cancer formation and stem cell regulation. However, the function of KLF4 in tumorigenesis and stem cell regulation are poorly understood d...
- Human Embryonic Stem Cells as Models for Aneuploid Chromosomal Syndromes
[作者:Biancotti, JC; Narwani, K; Buehler, N; Mandefro, B; Golan-Lev, T; Yanuka, O; Clark, A; Hill, D; Benvenisty, N; Lavon, N,期刊:Stem Cells, 页码:1530-1540 , 文章类型: Article,,卷期:2010年28-9]
- Syndromes caused by chromosomal aneuploidies are widely recognized genetic disorders in humans and often lead to spontaneous miscarriage. Preimplantation genetic screening is used to detect chromosomal aneuploidies in ea...
- Transplanted Oligodendrocytes and Motoneuron Progenitors Generated from Human Embryonic Stem Cells Promote Locomotor Recovery After Spinal Cord Transection
[作者:Erceg, S; Ronaghi, M; Oria, M; Rosello, MG; Arago, MAP; Lopez, MG; Radojevic, I; Moreno-Manzano, V; Rodriguez-Jimenez, FJ; Bhattacharya, SS; Cordoba, J; Stojkovic, M,期刊:Stem Cells, 页码:1541-1549 , 文章类型: Article,,卷期:2010年28-9]
- Human embryonic stem cells (hESC) hold great promise for the treatment of patients with many neurodegenerative diseases particularly those arising from cell loss or neural dysfunction including spinal cord injury. This s...
- Loss of Bright/ARID3a Function Promotes Developmental Plasticity
[作者:An, GY; Miner, CA; Nixon, JC; Kincade, PW; Bryant, J; Tucker, PW; Webb, CF,期刊:Stem Cells, 页码:1560-1567 , 文章类型: Article,,卷期:2010年28-9]
- B-cell regulator of immunoglobulin heavy chain transcription (Bright)/ARID3a, an A+T-rich interaction domain protein, was originally discovered in B lymphocyte lineage cells. However, expression patterns and high lethali...
- Adult Stem Cells Exhibit Global Suppression of RNA Polymerase II Serine-2 Phosphorylation
[作者:Freter, R; Osawa, M; Nishikawa, SI,期刊:Stem Cells, 页码:1571-1580 , 文章类型: Article,,卷期:2010年28-9]
- Adult stem cells, which are characterized by their capacity for self-renewal and differentiation, participate in tissue homeostasis and response to injury. They are thought to enter a state of relative quiescence, known ...
- G alpha Subunit Coordinates with Ephrin-B to Balance Self-Renewal and Differentiation in Neural Progenitor Cells
[作者:Murai, K; Qiu, RX; Zhang, HY; Wang, J; Wu, C; Neubig, RR; Lu, QA,期刊:Stem Cells, 页码:1581-1589 , 文章类型: Article,,卷期:2010年28-9]
- Proper development of the mammalian brain requires that neural progenitor cells balance self-renewal and differentiation under precise temporal and spatial regulation, but the underlying mechanisms are not well understoo...
- Mesenchymal Stem Cell-Dependent Formation of Heterotopic Tendon-Bone Insertions (Osteotendinous Junctions)
[作者:Shahab-Osterloh, S; Witte, F; Hoffmann, A; Winkel, A; Laggies, S; Neumann, B; Seiffart, V; Lindenmaier, W; Gruber, AD; Ringe, J; Haupl, T; Thorey, F; Willbold, E; Corbeau, P; Gross, G,期刊:Stem Cells, 页码:1590-1601 , 文章类型: Article,,卷期:2010年28-9]
- Ligament-to-bone and tendon-to-bone interfaces (entheses, osteotendinous junctions [OTJs]) serve to dissipate stress between soft tissue and bone. Surgical reconstruction of these interfaces is an issue of considerable i...
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