- NOTCH Pathway Blockade Depletes CD133-Positive Glioblastoma Cells and Inhibits Growth of Tumor Neurospheres and Xenografts
[作者:Fan, X; Khaki, L; Zhu, TS; Soules, ME; Talsma, CE; Gul, N; Koh, C; Zhang, JY; Li, YM; Maciaczyk, J; Nikkhah, G; DiMeco, F; Piccirillo, S; Vescovi, AL; Eberhart, CG,期刊:Stem Cells, 页码:5-16 , 文章类型: Article,,卷期:2010年28-1]
- Cancer stem cells (CSCs) are thought to be critical for the engraftment and long-term growth of many tumors, including glioblastoma (GBM). The cells are at least partially spared by traditional chemotherapies and radiati...
- Notch Promotes Radioresistance of Glioma Stem Cells
[作者:Wang, JL; Wakeman, TP; Lathia, JD; Hjelmeland, AB; Wang, XF; White, RR; Rich, JN; Sullenger, BA,期刊:Stem Cells, 页码:17-28 , 文章类型: Article,,卷期:2010年28-1]
- Radiotherapy represents the most effective nonsurgical treatments for gliomas. However, gliomas are highly radioresistant and recurrence is nearly universal. Results from our laboratory and other groups suggest that canc...
- Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells under Xeno-free Conditions
[作者:Rodriguez-Piza, I; Richaud-Patin, Y; Vassena, R; Gonzalez, F; Barrero, MJ; Veiga, A; Raya, A; Belmonte, JCI,期刊:Stem Cells, 页码:36-44 , 文章类型: Article,,卷期:2010年28-1]
- The availability of induced pluripotent stem cells (iPSCs) has created extraordinary opportunities for modeling and perhaps treating human disease. However, all reprogramming protocols used to date involve the use of pro...
- FGF2 Specifies hESC-Derived Definitive Endoderm into Foregut/Midgut Cell Lineages in a Concentration-Dependent Manner
[作者:Ameri, J; Stahlberg, A; Pedersen, J; Johansson, JK; Johannesson, MM; Artner, I; Semb, H,期刊:Stem Cells, 页码:45-56 , 文章类型: Article,,卷期:2010年28-1]
- Fibroblast growth factor (FGF) signaling controls axis formation during endoderm development. Studies in lower vertebrates have demonstrated that FGF2 primarily patterns the ventral foregut endoderm into liver and lung, ...
- Expression of GFP Under the Control of the RNA Helicase VASA Permits Fluorescence-Activated Cell Sorting Isolation of Human Primordial Germ Cells
[作者:Tilgner, K; Atkinson, SP; Yung, S; Golebiewska, A; Stojkovic, M; Moreno, R; Lako, M; Armstrong, L,期刊:Stem Cells, 页码:84-92 , 文章类型: Article,,卷期:2010年28-1]
- The isolation of significant numbers of human primordial germ cells at several developmental stages is important for investigations of the mechanisms by which they are able to undergo epigenetic reprogramming. Only small...
- Enhanced Hematovascular Contribution of SCL 3 ' Enhancer Expressing Fetal Liver Cells Uncovers Their Potential to Integrate in Extramedullary Adult Niches
[作者:Garcia-Ortega, AM; Canete, A; Quinter, C; Silberstein, L; Piquer-Gil, M; Alvarez-Dolado, M; Dekel, B; Gottgens, B; Sanchez, MJ,期刊:Stem Cells, 页码:100-112 , 文章类型: Article,,卷期:2010年28-1]
- Fetal liver (FL) hematopoietic progenitors have superior blood engraftment competence compared with adult bone marrow (BM), however less is known about FL in vivo vascular capacity. Here we show in transplantation assays...
- An FGF4-FRS2 alpha-Cdx2 Axis in Trophoblast Stem Cells Induces Bmp4 to Regulate Proper Growth of Early Mouse Embryos
[作者:Murohashi, M; Nakamura, T; Tanaka, S; Ichise, T; Yoshida, N; Yamamoto, T; Shibuya, M; Schlessinger, J; Gotoh, N,期刊:Stem Cells, 页码:113-121 , 文章类型: Article,,卷期:2010年28-1]
- A variety of stem cells are controlled by the actions of multiple growth factors in vitro. However, it remains largely unclear how growth factors control the proliferation and differentiation of stem cells in vivo. Here,...
- Brief Report: Interferon-gamma Induces Expansion of Lin(-)Sca-1(+)C-Kit(+) Cells
[作者:Zhao, X; Ren, GW; Liang, L; Ai, PZ; Zheng, B; Tischfield, JA; Shi, YF; Shao, CS,期刊:Stem Cells, 页码:122-126 , 文章类型: Article,,卷期:2010年28-1]
- The balance between Th1 and Th2 cells is critical for homeostasis of the immune system. Th1 cells can also regulate hematopoietic progenitor cell homeostasis by production of oncostatin M. Here we show that Th1 cell prod...
- Transplantation of Embryonic Neural Stem/Precursor Cells Overexpressing BM88/Cend1 Enhances the Generation of Neuronal Cells in the Injured Mouse Cortex
[作者:Makri, G; Lavdas, AA; Katsimpardi, L; Charneau, P; Thomaidou, D; Matsas, R,期刊:Stem Cells, 页码:127-139 , 文章类型: Article,,卷期:2010年28-1]
- The intrinsic inability of the central nervous system to efficiently repair traumatic injuries renders transplantation of neural stem/precursor cells (NPCs) a promising approach towards repair of brain lesions. In this s...
- Mesenchymal Cells Appearing in Pancreatic Tissue Culture Are Bone Marrow-Derived Stem Cells With the Capacity to Improve Transplanted Islet Function
[作者:Sordi, V; Melzi, R; Mercalli, A; Formicola, R; Doglioni, C; Tiboni, F; Ferrari, G; Nano, R; Chwalek, K; Lammert, E; Bonifacio, E; Piemonti, L,期刊:Stem Cells, 页码:140-151 , 文章类型: Article,,卷期:2010年28-1]
- Adherent fibroblast-like cells have been reported to appear in cultures of human endocrine or exocrine pancreatic tissue during attempts to differentiate human beta cells from pancreatic precursors. A thorough characteri...
- Evaluation of ABCG2 Expression in Human Embryonic Stem Cells: Crossing the Same River Twice?
[作者:Sarkadi, B; Orban, TI; Szakacs, G; Varady, G; Schamberger, A; Erdei, Z; Szebenyi, K; Homolya, L; Apati, A,期刊:Stem Cells, 页码:174-176 , 文章类型: Letter,,卷期:2010年28-1]
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