- Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Conversation with Il-Hoan Oh
[作者:Lako, M; Trounson, A; Daher, S,期刊:Stem Cells, 页码:2121-2123 , 文章类型: Editorial Material,,卷期:2010年28-12]
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- Characterizing the Contribution of Stem/Progenitor Cells to Tumorigenesis in the Pten(-/-) TP53(-/-) Prostate Cancer Model
[作者:Abou-Kheir, WG; Hynes, PG; Martin, PL; Pierce, R; Kelly, K,期刊:Stem Cells, 页码:2129-2140 , 文章类型: Article,,卷期:2010年28-12]
- Loss of PTEN is one of the most common mutations in prostate cancer, and loss of wild-type TP53 is associated with prostate cancer progression and castrate resistance. Modeling prostate cancer in the mouse has shown that...
- Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells
[作者:Jeong, CH; Cho, YY; Kim, MO; Kim, SH; Cho, EJ; Lee, SY; Jeon, YJ; Lee, KY; Yao, K; Keum, YS; Bode, AM; Dong, ZG,期刊:Stem Cells, 页码:2141-2150 , 文章类型: Article,,卷期:2010年28-12]
- Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by transduction of reprogramming factors, including Oct4, Sox2, Klf4, and c-Myc. A coordinated network of these factors was suggested to confe...
- In Vivo Assessment of the Electrophysiological Integration and Arrhythmogenic Risk of Myocardial Cell Transplantation Strategies
[作者:Gepstein, L; Ding, CH; Rehemedula, D; Wilson, EE; Yankelson, L; Caspi, O; Gepstein, A; Huber, I; Olgin, JE,期刊:Stem Cells, 页码:2151-2161 , 文章类型: Article,,卷期:2010年28-12]
- Cell replacement strategies are promising interventions aiming to improve myocardial performance. Yet, the electrophysiological impact of these approaches has not been elucidated. We assessed the electrophysiological con...
- Nestin Is Required for the Proper Self-Renewal of Neural Stem Cells
[作者:Park, D; Xiang, AP; Mao, FF; Zhang, L; Di, CG; Liu, XM; Shao, YA; Ma, BF; Lee, JH; Ha, KS; Walton, N; Lahn, BT,期刊:Stem Cells, 页码:2162-2171 , 文章类型: Article,,卷期:2010年28-12]
- The intermediate filament protein, nestin, is a widely employed marker of multipotent neural stem cells (NSCs). Recent in vitro studies have implicated nestin in a number of cellular processes, but there is no data yet o...
- An Immunoprotective Privilege of Corneal Epithelial Stem Cells Against Th17 Inflammatory Stress by Producing Glial Cell-Derived Neurotrophic Factor
[作者:Bian, F; Qi, H; Ma, P; Zhang, LL; Yoon, KC; Pflugfelder, SC; Li, DQ,期刊:Stem Cells, 页码:2172-2181 , 文章类型: Article,,卷期:2010年28-12]
- Adult stem cells are well known for their self-renewal and regenerative capacity. The mechanisms protecting these cells from inflammatory damage have not been well elucidated. This study investigated the immunoprotective...
- Hierarchization of Myogenic and Adipogenic Progenitors Within Human Skeletal Muscle
[作者:Pisani, DF; Clement, N; Loubat, A; Plaisant, M; Sacconi, S; Kurzenne, JY; Desnuelle, C; Dani, C; Dechesne, CA,期刊:Stem Cells, 页码:2182-2194 , 文章类型: Article,,卷期:2010年28-12]
- Skeletal muscle cells constitute a heterogeneous population that maintains muscle integrity through a high myogenic regenerative capacity. More unexpectedly, this population is also endowed with an adipogenic potential, ...
- Mitochondrial DNA Integrity Is Essential for Mitochondrial Maturation During Differentiation of Neural Stem Cells
[作者:Wang, W; Osenbroch, P; Skinnes, R; Esbensen, Y; Bjoras, M; Eide, L,期刊:Stem Cells, 页码:2195-2204 , 文章类型: Article,,卷期:2010年28-12]
- Differentiation of neural stem cells (NSCs) involves the activation of aerobic metabolism, which is dependent on mitochondrial function. Here, we show that the differentiation of NSCs involves robust increases in mitocho...
- Irradiation Enhances the Tumor Tropism and Therapeutic Potential of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Secreting Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Glioma Therapy
[作者:Kim, SM; Oh, JH; Park, SA; Ryu, CH; Lim, JY; Kim, DS; Chang, JW; Oh, W; Jeun, SS,期刊:Stem Cells, 页码:2217-2228 , 文章类型: Article,,卷期:2010年28-12]
- Irradiation is a standard therapy for gliomas and many other cancers. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is one of the most promising candidates for cancer gene therapy. Here, we show that tu...
- Antibacterial Effect of Human Mesenchymal Stem Cells Is Mediated in Part from Secretion of the Antimicrobial Peptide LL-37
[作者:Krasnodembskaya, A; Song, YL; Fang, XH; Gupta, N; Serikov, V; Lee, JW; Matthay, MA,期刊:Stem Cells, 页码:2229-2238 , 文章类型: Article,,卷期:2010年28-12]
- Recent in vivo studies indicate that mesenchymal stem cells (MSCs) may have beneficial effects in the treatment of sepsis induced by bacterial infection. Administration of MSCs in these studies improved survival and enha...
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