- Interaction of J-Protein Co-Chaperone Jac1 with Fe-S Scaffold Isu Is Indispensable In Vivo and Conserved in Evolution
[作者:Ciesielski, SJ; Schilke, BA; Osipiuk, J; Bigelow, L; Mulligan, R; Majewska, J; Joachimiak, A; Marszalek, J; Craig, EA; Dutkiewicz, R,期刊:Journal of Molecular Biology, 页码:1-12 , 文章类型: Article,,卷期:2012年417-40910]
- The ubiquitous mitochondrial J-protein Jac1, called HscB in Escherichia coli, and its partner Hsp70 play a critical role in the transfer of Fe-S clusters from the scaffold protein Isu to recipient proteins. Biochemical r...
- Nickel Binding and [NiFe]-Hydrogenase Maturation by the Metallochaperone SlyD with a Single Metal-Binding Site in Escherichia coil
[作者:Kaluarachchi, H; Altenstein, M; Sugumar, SR; Balbach, J; Zamble, DB; Haupt, C,期刊:Journal of Molecular Biology, 页码:28-35 , 文章类型: Article,,卷期:2012年417-40910]
- SlyD (sensitive to lysis D) is a nickel metallochaperone involved in the maturation of [NiFe]-hydrogenases in Escherichia coli (E. coli) and specifically contributes to the nickel delivery step during enzyme biosynthesis...
- DLK2 Is a Transcriptional Target of KLF4 in the Early Stages of Adipogenesis
[作者:Rivero, S; Diaz-Guerra, MJM; Monsalve, EM; Laborda, J; Garcia-Ramirez, JJ,期刊:Journal of Molecular Biology, 页码:36-50 , 文章类型: Article,,卷期:2012年417-40910]
- The epidermal growth factor-like protein DLK2, highly homologous to DLK1, has been identified as a modulator of adipogenesis in vitro. Knocking down Dlk2 expression prevents a dipogenesis of 3T3-L1 cells but enhances tha...
- The C-Terminal Tail of Human Neuronal Calcium Sensor 1 Regulates the Conformational Stability of the Ca2+-Activated State
[作者:Heidarsson, PO; Bjerrum-Bohr, IJ; Jensen, GA; Pongs, O; Finn, BE; Poulsen, FM; Kragelund, BB,期刊:Journal of Molecular Biology, 页码:51-64 , 文章类型: Article,,卷期:2012年417-40910]
- Neuronal calcium sensor 1 (NCS-1) and orthologs are expressed in all organisms from yeast to humans. In the latter, NCS-1 plays an important role in neurotransmitter release and interacts with a plethora of binding partn...
- Isolation of an Asymmetric RNA Uncoating Intermediate for a Single-Stranded RNA Plant Virus
[作者:Bakker, SE; Ford, RJ; Barker, AM; Robottom, J; Saunders, K; Pearson, AR; Ranson, NA; Stockley, PG,期刊:Journal of Molecular Biology, 页码:65-78 , 文章类型: Article,,卷期:2012年417-40910]
- We have determined the three-dimensional structures of both native and expanded forms of turnip crinkle virus (TCV), using cryo-electron microscopy, which allows direct visualization of the encapsidated single-stranded R...
- Modulation of the Interaction between Neurotensin Receptor NTS1 and Gq Protein by Lipid
[作者:Inagaki, S; Ghirlando, R; White, JF; Gvozdenovic-Jeremic, J; Northup, JK; Grisshammer, R,期刊:Journal of Molecular Biology, 页码:95-111 , 文章类型: Article,,卷期:2012年417-40910]
- Membrane lipids have been implicated to influence the activity of G-protein-coupled receptors (GPCRs). Almost all of our knowledge on the role of lipids on GPCR and G protein function comes from work on the visual pigmen...
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