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  • Proteosome Inhibitor Oncolytic
    [作者:Davies, S; Pandian, R; Bolos, J; Castaner, R,期刊:Drugs of the Future, 页码:708-716 , 文章类型: Article,,卷期:2009年34-9]
  • Proteosome inhibitors ore a new class of drugs that hove been shown to be cytotoxic and to induce apoptosis in tumor cells, particularly multiple myelomo (MM). In a bid to overcome the dose-limiting toxicity and adverse ...
  • ADVANCES IN SYSTEMIC siRNA DELIVERY
    [作者:Leng, Q; Woodle, MC; Lu, PY; Mixson, AJ,期刊:Drugs of the Future, 页码:721-737 , 文章类型: Review,,卷期:2009年34-9]
  • Sequence-specific gene silencing with small interfering RNA (SiRNA) has transformed basic science research, and the efficacy of siRNA therapeutics in a variety of diseases is now being evaluated in preclinical and clinic...
  • THERAPEUTIC TARGETS FOR SEPSIS
    [作者:Sorbera, L; Dulsat, C; Rosa, E,期刊:Drugs of the Future, 页码:765-770 , 文章类型: Article,,卷期:2009年34-9]
  • Sepsis is the initial systemic inflammatory response syndrome (SIRS) associated with a confirmed infectious process. It is a spectrum of clinical conditions caused by the immune response of a host to severe infection (e....