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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共8条记录   DIAZEPINOMICIN Apoptosis Inducer Oncolytic [作者：Campas, C,期刊：Drugs of the Future, 页码：349-351 , 文章类型： Article，,卷期：2009年34-5] Diazepinomicin is a structurally novel farnesylated dibenzodiazepinone discovered using a drug discovery platform (DECIPHER) designed for the screening of anticancer compounds from actinomycete cultures. Preclinical data... GOLIMUMAB Human Anti-TNF-alpha Monoclonal Antibody Treatment of Inflammation [作者：Dulsat, C; Mealy, N,期刊：Drugs of the Future, 页码：352-357 , 文章类型： Article，,卷期：2009年34-5] Golimumab (CNTO-148, Simponi (TM)) is a new human monoclonal-antibody under development by Centocor that targets and neutralizes the proinflammatory cytokine TNF-alpha This review summarizes in vitro and in vivo publicat... VORELOXIN DNA-Intercalating Drug Topoisomerase II Inhibitor Oncolytic [作者：Moualla, H; Mills, DA; Hromas, R; Verschraegen, CF,期刊：Drugs of the Future, 页码：363-374 , 文章类型： Article，,卷期：2009年34-5] Voreloxin (SNS-595) is being developed by Sunesis Pharmaceuticals under license from Dainippon Sumitomo Pharmo for the treatment of a variety of solid and hematological malignancies. Voreloxin is a naphthyridine derivati... ANTI-CS1 ANTIBODIES: A NEW THERAPEUTIC APPROACH TO TREAT MULTIPLE MYELOMA [作者：Hsi, ED; Afar, D,期刊：Drugs of the Future, 页码：375-379 , 文章类型： Review，,卷期：2009年34-5] CS1 (CD319) is a member of the signaling lymphocytic activation molecule (SLAM) family of cell-surface proteins. It is expressed on natural killer cells and subsets of T and B cells. As part of a screening program to ide... PHARMACOLOGICAL TREATMENTS FOR TINNITUS: NEW AND OLD [作者：Salvi, R; Loborinas, E; Sun, W,期刊：Drugs of the Future, 页码：381-400 , 文章类型： Review，,卷期：2009年34-5] Subjective tinnitus, the phantom ringing or buzzing sensation that occurs in the absence of sound, affects 12-74% of adults,in some cases the tinnitus is so severe or disabling that patients seek medical treatment. Howev... JX-594 Recombinant Vaccinia Virus Expressing GMCSF Oncolytic [作者：Kim, SG; Hwang, TH,期刊：Drugs of the Future, 页码：358-362 , 文章类型： Article，,卷期：2009年34-5] JX-594 is derived by inserting human GMCSF genes under the control of earlyllote promoters into the thymidine kinase (TK) genes of the vaccinia virus. JX-594 was well tolerated when administered intratumorally to patient... THERAPEUTIC TARGETS FOR MULTIPLE SCLEROSIS [作者：Sorbera, LA; Dulsat, C; Rosa, E,期刊：Drugs of the Future, 页码：405-417 , 文章类型： Article，,卷期：2009年34-5] Multiple sclerosis (MS) is on inflammatory disorder of the brain and spinal cord in which focal lymphocytic infiltration leads to myelin and oxonol damage. Although first described in the 14th century, MS was untreatable... KAWASAKI'S DISEASE [作者：Dulsat, C; Mealy, N,期刊：Drugs of the Future, 页码：401-404 , 文章类型： Article，,卷期：2009年34-5] Effective therapies to reduce the acute symptoms of the pediatric syndrome Kawasaki's disease can prevent the development of future cardiovascular complications, particularly fatal coronary artery aneurysms. The first li...