- The role of FGF/Erk signaling in pluripotent cells
[作者：Lanner, F; Rossant, J,期刊：Development, 页码：3351-3360 , 文章类型： Review，,卷期：2010年137-20]
- Fibroblast growth factor (FGF) signaling controls fundamental processes such as proliferation, differentiation and migration throughout mammalian development. Here we discuss recent discoveries that implicate FGF/Erk sig...
- zif-1 translational repression defines a second, mutually exclusive OMA function in germline transcriptional repression
[作者：Guven-Ozkan, T; Robertson, SM; Nishi, Y; Lin, RL,期刊：Development, 页码：3373-3382 , 文章类型： Article，,卷期：2010年137-20]
- Specification of primordial germ cells requires global repression of transcription. In C. elegans, primordial germ cells are generated through four rounds of asymmetric divisions, starting from the zygote P0, each produc...
- Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E-cadherin
[作者：Stephenson, RO; Yamanaka, Y; Rossant, J,期刊：Development, 页码：3383-3391 , 文章类型： Article，,卷期：2010年137-20]
- The first two cell lineages in the mouse, the surface trophectoderm (TE) and inner cell mass (ICM), are morphologically distinguishable by E3.5, with the outer TE forming a polarized epithelial layer enclosing the apolar...
- The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells
[作者：Fernandez-Diaz, LC; Laurent, A; Girasoli, S; Turco, M; Longobardi, E; Iotti, G; Jenkins, NA; Fiorenza, MT; Copeland, NG; Blasi, F,期刊：Development, 页码：3393-3403 , 文章类型： Article，,卷期：2010年137-20]
Disruption of mouse Prep1, which codes for a homeodomain transcription factor, leads to embryonic lethality during postimplantation stages. Prep1(-/-)embryos stop developing after implantation and before anterior visc...
- Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape
[作者：Young, NM; Chong, HJ; Hu, DAE; Hallgrimsson, B; Marcucio, RS,期刊：Development, 页码：3405-3409 , 文章类型： Article，,卷期：2010年137-20]
- Variation is an intrinsic feature of biological systems, yet developmental biology does not frequently address population-level phenomena. Sonic hedgehog (SHH) signaling activity in the vertebrate forebrain and face is t...
- Planar cell polarity: the orientation of larval denticles in Drosophila appears to depend on gradients of Dachsous and Fat
[作者：Repiso, A; Saavedra, P; Casal, J; Lawrence, PA,期刊：Development, 页码：3411-3415 , 文章类型： Article，,卷期：2010年137-20]
- The larval ventral belts of Drosophila consist of six to seven rows of denticles that are oriented, some pointing forwards, some backwards. We present evidence that denticle orientation is determined almost entirely by D...
- Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb
[作者：Zhang, Z; Sui, PF; Dong, AW; Hassell, J; Cserjesi, P; Chen, YT; Behringer, RR; Sun, X,期刊：Development, 页码：3417-3426 , 文章类型： Article，,卷期：2010年137-20]
- Preaxial polydactyly (PPD) is a common limb-associated birth defect characterized by extra digit(s) in the anterior autopod. It often results from ectopic sonic hedgehog (Shh) expression in the anterior limb bud. Althoug...
- Generation of distinct signaling modes via diversification of the Egfr ligand-processing cassette
[作者：Rousso, T; Lynch, J; Yogev, S; Roth, S; Schejter, ED; Shilo, BZ,期刊：Development, 页码：3427-3437 , 文章类型： Article，,卷期：2010年137-20]
- Egfr ligand processing in Drosophila involves trafficking of the ligand precursor by the chaperone Star from the endoplasmic reticulum ( ER) to a secretory compartment, where the precursor is cleaved by the intramembrane...
- FGF8 acts as a classic diffusible morphogen to pattern the neocortex
[作者：Toyoda, R; Assimacopoulos, S; Wilcoxon, J; Taylor, A; Feldman, P; Suzuki-Hirano, A; Shimogori, T; Grove, EA,期刊：Development, 页码：3439-3448 , 文章类型： Article，,卷期：2010年137-20]
- Gain- and loss-of-function experiments have demonstrated that a source of fibroblast growth factor (FGF) 8 regulates anterior to posterior (A/P) in the neocortical area map. Whether FGF8 controls patterning as a classic ...
- Integrin alpha V is necessary for gastrulation movements that regulate vertebrate body asymmetry
[作者：Ablooglu, AJ; Tkachenko, E; Kang, JA; Shattil, SJ,期刊：Development, 页码：3449-3458 , 文章类型： Article，,卷期：2010年137-20]
- Integrin alpha V can form heterodimers with several beta subunits to mediate cell-cell and cell-extracellular matrix interactions. During zebrafish gastrulation, alpha V is expressed maternally and zygotically. Here, we ...
- Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ
[作者：Oteiza, P; Koppen, M; Krieg, M; Pulgar, E; Farias, C; Melo, C; Preibisch, S; Muller, D; Tada, M; Hartel, S; Heisenberg, CP; Concha, ML,期刊：Development, 页码：3459-3468 , 文章类型： Article，,卷期：2010年137-20]
- Organ formation requires the precise assembly of progenitor cells into a functional multicellular structure. Mechanical forces probably participate in this process but how they influence organ morphogenesis is still uncl...
- A prominent requirement for single-minded and the ventral midline in patterning the dorsoventral axis of the crustacean Parhyale hawaiensis
[作者：Vargas-Vila, MA; Hannibal, RL; Parchem, RJ; Liu, PZ; Patel, NH,期刊：Development, 页码：3469-3476 , 文章类型： Article，,卷期：2010年137-20]
- In bilaterians, establishing the correct spatial positioning of structures along the dorsoventral (DV) axis is essential for proper embryonic development. Insects such as Drosophila rely on the Dorsal activity gradient a...
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