- Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in Caenorhabditis elegans
[作者：Ogura, K; Okada, T; Mitani, S; Gengyo-Ando, K; Baillie, DL; Kohara, Y; Goshima, Y,期刊：Development, 页码：1657-1667 , 文章类型： Article，,卷期：2010年137-10]
- UNC-51 is a serine/threonine protein kinase conserved from yeast to humans. The yeast homolog Atg1 regulates autophagy (catabolic membrane trafficking) required for surviving starvation. In C. elegans, UNC-51 regulates t...
- Symmetry breaking and polarization of the C. elegans zygote by the polarity protein PAR-2
[作者：Zonies, S; Motegi, F; Hao, YS; Seydoux, G,期刊：Development, 页码：1669-1677 , 文章类型： Article，,卷期：2010年137-10]
- Polarization of the C. elegans zygote is initiated by ECT-2-dependent cortical flows, which mobilize the anterior PAR proteins (PAR-3, PAR-6 and PKC-3) away from the future posterior end of the embryo marked by the sperm...
- A novel F-box protein is required for caspase activation during cellular remodeling in Drosophila
[作者：Bader, M; Arama, E; Steller, H,期刊：Development, 页码：1679-1688 , 文章类型： Article，,卷期：2010年137-10]
- Terminal differentiation of male germ cells in Drosophila and mammals requires extensive cytoarchitectural remodeling, the elimination of many organelles, and a large reduction in cell volume. The associated process, ter...
- Biogenesis of GPI-anchored proteins is essential for surface expression of sodium channels in zebrafish Rohon-Beard neurons to respond to mechanosensory stimulation
[作者：Nakano, Y; Fujita, M; Ogino, K; Saint-Amant, L; Kinoshita, T; Oda, Y; Hirata, H,期刊：Development, 页码：1689-1698 , 文章类型： Article，,卷期：2010年137-10]
- In zebrafish, Rohon-Beard (RB) neurons are primary sensory neurons present during the embryonic and early larval stages. At 2 days post-fertilization (dpf), wild-type zebrafish embryos respond to mechanosensory stimulati...
- Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes
[作者：Sun, FY; Palmer, K; Handel, MA,期刊：Development, 页码：1699-1707 , 文章类型： Article，,卷期：2010年137-10]
- The ENU-induced repro8 mutation was identified in a screen to uncover genes that control mouse gametogenesis. repro8 causes male-limited infertility, with failure of spermatocytes to exit meiotic prophase via the G2/MI t...
- Maternal activation of gap genes in the hover fly Episyrphus
[作者：Lemke, S; Busch, SE; Antonopoulos, DA; Meyer, F; Domanus, MH; Schmidt-Ott, U,期刊：Development, 页码：1709-1719 , 文章类型： Article，,卷期：2010年137-10]
- The metameric organization of the insect body plan is initiated with the activation of gap genes, a set of transcription-factor-encoding genes that are zygotically expressed in broad and partially overlapping domains alo...
- Dysregulation of cell-to-cell connectivity and stomatal patterning by loss-of-function mutation in Arabidopsis CHORUS (GLUCAN SYNTHASE-LIKE 8)
[作者：Guseman, JM; Lee, JS; Bogenschutz, NL; Peterson, KM; Virata, RE; Xie, B; Kanaoka, MM; Hong, ZL; Torii, KU,期刊：Development, 页码：1731-1741 , 文章类型： Article，,卷期：2010年137-10]
- Patterning of stomata, valves on the plant epidermis, requires the orchestrated actions of signaling components and cell-fate determinants. To understand the regulation of stomatal patterning, we performed a genetic scre...
- Sunspot, a link between Wingless signaling and endoreplication in Drosophila
[作者：Taniue, K; Nishida, A; Hamada, F; Sugie, A; Oda, T; Ui-Tei, K; Tabata, T; Akiyama, T,期刊：Development, 页码：1755-1764 , 文章类型： Article，,卷期：2010年137-10]
- The Wingless (Wg)/Wnt signaling pathway is highly conserved throughout many multicellular organisms. It directs the development of diverse tissues and organs by regulating important processes such as proliferation, polar...
- Bazooka is required for polarisation of the Drosophila anterior-posterior axis
[作者：Doerflinger, H; Vogt, N; Torres, IL; Mirouse, V; Koch, I; Nusslein-Volhard, C; St Johnston, D,期刊：Development, 页码：1765-1773 , 文章类型： Article，,卷期：2010年137-10]
- The Drosophila anterior-posterior (AP) axis is determined by the polarisation of the stage 9 oocyte and the subsequent localisation of bicoid and oskar mRNAs to opposite poles of the cell. Oocyte polarity has been propos...
- Opposing Fgf and Bmp activities regulate the specification of olfactory sensory and respiratory epithelial cell fates
[作者：Maier, E; von Hofsten, J; Nord, H; Fernandes, M; Paek, H; Hebert, JM; Gunhaga, L,期刊：Development, 页码：1601-1611 , 文章类型： Article，,卷期：2010年137-10]
- The olfactory sensory epithelium and the respiratory epithelium are derived from the olfactory placode. However, the molecular mechanisms regulating the differential specification of the sensory and the respiratory epith...
- Genomic cis-regulatory networks in the early Ciona intestinalis embryo
[作者：Kubo, A; Suzuki, N; Yuan, XY; Nakai, K; Satoh, N; Imai, KS; Satou, Y,期刊：Development, 页码：1613-1623 , 文章类型： Article，,卷期：2010年137-10]
- Precise spatiotemporal gene expression during animal development is achieved through gene regulatory networks, in which sequence-specific transcription factors (TFs) bind to cis-regulatory elements of target genes. Altho...
- Interdependence of macrophage migration and ventral nerve cord development in Drosophila embryos
[作者：Evans, IR; Hu, N; Skaer, H; Wood, W,期刊：Development, 页码：1625-1633 , 文章类型： Article，,卷期：2010年137-10]
- During embryonic development, Drosophila macrophages (haemocytes) undergo a series of stereotypical migrations to disperse throughout the embryo. One major migratory route is along the ventral nerve cord (VNC), where hae...
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