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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共15条记录   The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the expression of synaptonemal complex proteins in germline stem cells [作者：Merritt, C; Seydoux, G,期刊：Development, 页码：1787-1798 , 文章类型： Article，,卷期：2010年137-11] FBF-1 and FBF-2 (collectively FBF) are two nearly identical Puf-domain RNA-binding proteins that regulate the switch from mitosis to meiosis in the C. elegans germline. In germline stem cells, FBF prevents premature meio... The Groucho ortholog UNC-37 interacts with the short Groucho-like protein LSY-22 to control developmental decisions in C. elegans [作者：Flowers, EB; Poole, RJ; Tursun, B; Bashllari, E; Pe'er, I; Hobert, O,期刊：Development, 页码：1799-1805 , 文章类型： Article，,卷期：2010年137-11] Transcriptional co-repressors of the Groucho/TLE family are important regulators of development in many species. A subset of Groucho/TLE family members that lack the C-terminal WD40 domains have been proposed to act as d... Production of Wnt4b by floor plate cells is essential for the segmental patterning of the vertebral column in medaka [作者：Inohaya, K; Takano, Y; Kudo, A,期刊：Development, 页码：1807-1813 , 文章类型： Article，,卷期：2010年137-11] The floor plate is a key organizer that controls the specification of neurons in the central nervous system. Here, we show a new role of the floor plate: segmental pattern formation of the vertebral column. Analysis of a... Lipid phosphate phosphatase activity regulates dispersal and bilateral sorting of embryonic germ cells in Drosophila [作者：Renault, AD; Kunwar, PS; Lehmann, R,期刊：Development, 页码：1815-1823 , 文章类型： Article，,卷期：2010年137-11] In Drosophila, germ cell survival and directionality of migration are controlled by two lipid phosphate phosphatases (LPP), wunen (wun) and wunen-2 (wun2). wun wun2 double mutant analysis reveals that the two genes, here... The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor [作者：Vaccari, T; Duchi, S; Cortese, K; Tacchetti, C; Bilder, D,期刊：Development, 页码：1825-1832 , 文章类型： Article，,卷期：2010年137-11] Evidence indicates that endosomal entry promotes signaling by the Notch receptor, but the mechanisms involved are not clear. In a search for factors that regulate Notch activation in endosomes, we isolated mutants in Dro... PAR-3 mediates the initial clustering and apical localization of junction and polarity proteins during C. elegans intestinal epithelial cell polarization [作者：Achilleos, A; Wehman, AM; Nance, J,期刊：Development, 页码：1833-1842 , 文章类型： Article，,卷期：2010年137-11] The apicobasal polarity of epithelial cells is critical for organ morphogenesis and function, and loss of polarity can promote tumorigenesis. Most epithelial cells form when precursor cells receive a polarization cue, de... Jagged-Notch signaling ensures dorsal skeletal identity in the vertebrate face [作者：Zuniga, E; Stellabotte, F; Crump, JG,期刊：Development, 页码：1843-1852 , 文章类型： Article，,卷期：2010年137-11] The development of the vertebrate face relies on the regionalization of neural crest-derived skeletal precursors along the dorsoventral (DV) axis. Here we show that Jagged-Notch signaling ensures dorsal identity within t... Apparent role of Tribolium orthodenticle in anteroposterior blastoderm patterning largely reflects novel functions in dorsoventral axis formation and cell survival [作者：Kotkamp, K; Klingler, M; Schoppmeier, M,期刊：Development, 页码：1853-1862 , 文章类型： Article，,卷期：2010年137-11] In the short-germ beetle Tribolium castaneum, the head gap gene orthodenticle (Tc-otd) has been proposed to functionally substitute for bicoid, the anterior morphogen unique to higher dipterans. In this study we reanalyz... Notch signaling, wt1 and foxc2 are key regulators of the podocyte gene regulatory network in Xenopus [作者：White, JT; Zhang, B; Cerqueira, DM; Tran, U; Wessely, O,期刊：Development, 页码：1863-1873 , 文章类型： Article，,卷期：2010年137-11] Podocytes are highly specialized cells in the vertebrate kidney. They participate in the formation of the size-exclusion barrier of the glomerulus/glomus and recruit mesangial and endothelial cells to form a mature glome... Zinc finger genes Fezf1 and Fezf2 control neuronal differentiation by repressing Hes5 expression in the forebrain [作者：Shimizu, T; Nakazawa, M; Kani, S; Bae, YK; Shimizu, T; Kageyama, R; Hibi, M,期刊：Development, 页码：1875-1885 , 文章类型： Article，,卷期：2010年137-11] Precise control of neuronal differentiation is necessary for generation of a variety of neurons in the forebrain. However, little is known about transcriptional cascades, which initiate forebrain neurogenesis. Here we sh... The miR-143-adducin3 pathway is essential for cardiac chamber morphogenesis [作者：Deacon, DC; Nevis, KR; Cashman, TJ; Zhou, Y; Zhao, L; Washko, D; Guner-Ataman, B; Burns, CG; Burns, CE,期刊：Development, 页码：1887-1896 , 文章类型： Article，,卷期：2010年137-11] Discovering the genetic and cellular mechanisms that drive cardiac morphogenesis remains a fundamental goal, as three-dimensional architecture greatly impacts functional capacity. During development, accurately contoured... The basic helix-loop-helix transcription factor Nato3 controls neurogenic activity in mesencephalic floor plate cells [作者：Ono, Y; Nakatani, T; Minaki, Y; Kumai, M,期刊：Development, 页码：1897-1906 , 文章类型： Article，,卷期：2010年137-11] Floor plate (FP) cells, the ventral midline cells of the developing neural tube, have long been thought to be non-neurogenic organizer cells that control neuronal patterning and axonal guidance. Recent studies have revea... Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors [作者：Lizarraga, SB; Margossian, SP; Harris, MH; Campagna, DR; Han, AP; Blevins, S; Mudbhary, R; Barker, JE; Walsh, CA; Fleming, MD,期刊：Development, 页码：1907-1917 , 文章类型： Article，,卷期：2010年137-11] Microcephaly affects similar to 1% of the population and is associated with mental retardation, motor defects and, in some cases, seizures. We analyzed the mechanisms underlying brain size determination in a mouse model ... The BMP pathway acts to directly regulate Tbx20 in the developing heart [作者：Mandel, EM; Kaltenbrun, E; Callis, TE; Zeng, XXI; Marques, SR; Yelon, D; Wang, DZ; Conlon, FL,期刊：Development, 页码：1919-1929 , 文章类型： Article，,卷期：2010年137-11] TBX20 has been shown to be essential for vertebrate heart development. Mutations within the TBX20 coding region are associated with human congenital heart disease, and the loss of Tbx20 in a wide variety of model systems... From shared lineage to distinct functions: the development of the inner ear and epibranchial placodes [作者：Ladher, RK; O'Neill, P; Begbie, J,期刊：Development, 页码：1777-1785 , 文章类型： Review，,卷期：2010年137-11] The inner ear and the epibranchial ganglia constitute much of the sensory system in the caudal vertebrate head. The inner ear consists of mechanosensory hair cells, their neurons, and structures necessary for sound and b...