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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共75条记录   Characterization of Erg K+ Channels in alpha- and beta-Cells of Mouse and Human Islets [作者：Hardy, AB; Fox, JEM; Giglou, PR; Wijesekara, N; Bhattacharjee, A; Sultan, S; Gyulkhandanyan, AV; Gaisano, HY; MacDonald, PE; Wheeler, MB,期刊：Journal of Biological Chemistry, 页码：30441-30452 , 文章类型： Article，,卷期：2009年284-44] Voltage-gated eag-related gene (Erg) K+ channels regulate the electrical activity of many cell types. Data regarding Erg channel expression and function in electrically excitable glucagon and insulin producing cells of t... Human BAMBI Cooperates with Smad7 to Inhibit Transforming Growth Factor-beta Signaling [作者：Yan, XH; Lin, ZH; Chen, F; Zhao, XG; Chen, H; Ning, YH; Chen, YG,期刊：Journal of Biological Chemistry, 页码：30097-30104 , 文章类型： Article，,卷期：2009年284-44] Transforming growth factor beta (TGF-beta) and related growth factors are essential regulators of embryogenesis and tissue homeostasis. The signaling pathways mediated by their receptors and Smad proteins are precisely m... Highly Conserved Small Subunit Residues Influence Rubisco Large Subunit Catalysis [作者：Genkov, T; Spreitzer, RJ,期刊：Journal of Biological Chemistry, 页码：30105-30112 , 文章类型： Article，,卷期：2009年284-44] The chloroplast enzyme ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco) catalyzes the rate-limiting step of photosynthetic CO2 fixation. With a deeper understanding of its structure-function relationships and co... Activation of the Liver X Receptor Prevents Lipopolysaccharide-induced Lung Injury [作者：Gong, HBA; He, JH; Lee, JH; Mallick, E; Gao, X; Li, S; Homanics, GE; Xie, W,期刊：Journal of Biological Chemistry, 页码：30113-30121 , 文章类型： Article，,卷期：2009年284-44] The liver X receptors (LXRs) have been known as sterol sensors that impact cholesterol and lipid homeostasis, as well as inflammation. Although the hepatic functions of LXRs are well documented, whether and how LXRs play... Direct Fe2+ Sensing by Iron-responsive Messenger RNA.Repressor Complexes Weakens Binding [作者：Khan, MA; Walden, WE; Goss, DJ; Theil, EC,期刊：Journal of Biological Chemistry, 页码：30122-30128 , 文章类型： Article，,卷期：2009年284-44] Fe2+ is now shown to weaken binding between ferritin and mitochondrial aconitase messenger RNA noncoding regulatory structures ((iron-responsive element) (IRE)-RNAs) and the regulatory proteins (IRPs), which adds a direc... Diversity and Developmental Expression of L-type Calcium Channel beta 2 Proteins and Their Influence on Calcium Current in Murine Heart [作者：Link, S; Meissner, M; Held, B; Beck, A; Weissgerber, P; Freichel, M; Flockerzi, V,期刊：Journal of Biological Chemistry, 页码：30129-30137 , 文章类型： Article，,卷期：2009年284-44] By now, little is known on L-type calcium channel (LTCC) subunits expressed in mouse heart. We show that CaV beta 2 proteins are the major CaV beta components of the LTCC in embryonic and adult mouse heart, but that in e... SIP30 Is Regulated by ERK in Peripheral Nerve Injury-induced Neuropathic Pain [作者：Peng, GD; Han, M; Du, YM; Lin, AN; Yu, L; Zhang, YQ; Jing, NH,期刊：Journal of Biological Chemistry, 页码：30138-30147 , 文章类型： Article，,卷期：2009年284-44] ERK plays an important role in chronic neuropathic pain. However, the underlying mechanism is largely unknown. Here we show that in chronic constriction injury-treated rat spinal cords, up-regulation of SIP30 (SNAP25-int... Analysis of PTEN Complex Assembly and Identification of Heterogeneous Nuclear Ribonucleoprotein C as a Component of the PTEN-associated Complex [作者：Mosessian, S; Avliyakulov, NK; Mulholland, DJ; Boontheung, P; Loo, JA; Wu, H,期刊：Journal of Biological Chemistry, 页码：30159-30166 , 文章类型： Article，,卷期：2009年284-44] PTEN (phosphatase and tensin homolog deleted on chromosome 10) is well characterized for its role in antagonizing the phosphoinositide 3-kinase pathway. Previous studies using size-exclusion chromatography demonstrated P... Ror2 Receptor Requires Tyrosine Kinase Activity to Mediate Wnt5A Signaling [作者：Mikels, A; Minami, Y; Nusse, R,期刊：Journal of Biological Chemistry, 页码：30167-30176 , 文章类型： Article，,卷期：2009年284-44] The Wnts include a large family of secreted proteins that serve as important signals during embryonic development and adult homeostasis. In the most well understood Wnt signaling pathway, Wnt binding to Frizzled and low ... Characterization of a Functional ZBP-89 Binding Site That Mediates Gata1 Gene Expression during Hematopoietic Development [作者：Ohneda, K; Ohmori, S; Ishijima, Y; Nakano, M; Yamamoto, M,期刊：Journal of Biological Chemistry, 页码：30187-30199 , 文章类型： Article，,卷期：2009年284-44] GATA-1 is a lineage-restricted transcription factor that plays essential roles in hematopoietic development. The Gata1 gene hematopoietic enhancer allowed Gata1 reporter expression in erythroid cells and megakaryocytes o... Insulin-stimulated Phosphorylation of the Rab GTPase-activating Protein TBC1D1 Regulates GLUT4 Translocation [作者：Peck, GR; Chavez, JA; Roach, WG; Budnik, BA; Lane, WS; Karlsson, HKR; Zierath, JR; Lienhard, GE,期刊：Journal of Biological Chemistry, 页码：30016-30023 , 文章类型： Article，,卷期：2009年284-44] Insulin stimulates the translocation of the glucose transporter GLUT4 from intracellular locations to the plasma membrane in adipose and muscle cells. Prior studies have shown that Akt phosphorylation of the Rab GTPase-a... Characterization of a Disease-associated Mutation Affecting a Putative Splicing Regulatory Element in Intron 6b of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene [作者：Faa, V; Incani, F; Meloni, A; Corda, D; Masala, M; Baffico, AM; Seia, M; Cao, A; Rosatelli, MC,期刊：Journal of Biological Chemistry, 页码：30024-30031 , 文章类型： Article，,卷期：2009年284-44] Cystic fibrosis (CF) is a common recessive disorder caused by > 1600 mutations in the CF transmembrane conductance regulator (CFTR) gene. About 13% of CFTR mutations are classified as "splicing mutations," but for almost... The Transcriptional Repressor CcpN from Bacillus subtilis Uses Different Repression Mechanisms at Different Promoters [作者：Licht, A; Brantl, S,期刊：Journal of Biological Chemistry, 页码：30032-30038 , 文章类型： Article，,卷期：2009年284-44] CcpN, a transcriptional repressor from Bacillus subtilis that is responsible for the carbon catabolite repression of three genes, has been characterized in detail in the past 4 years. However, nothing is known about the ... Mcl-1 Degradation during Hepatocyte Lipoapoptosis [作者：Masuoka, HC; Mott, J; Bronk, SF; Werneburg, NW; Akazawa, Y; Kaufmann, SH; Gores, GJ,期刊：Journal of Biological Chemistry, 页码：30039-30048 , 文章类型： Article，,卷期：2009年284-44] The mechanisms of free fatty acid-induced lipoapoptosis are incompletely understood. Here we demonstrate that Mcl-1, an anti-apoptotic member of the Bcl-2 family, was rapidly degraded in hepatocytes in response to palmit... Interferons Direct an Effective Innate Response to Legionella pneumophila Infection [作者：Plumlee, CR; Lee, C; Beg, AA; Decker, T; Shuman, HA; Schindler, C,期刊：Journal of Biological Chemistry, 页码：30058-30066 , 文章类型： Article，,卷期：2009年284-44] Legionella pneumophila remains an important opportunistic pathogen of human macrophages. Its more limited ability to replicate in murine macrophages has been attributed to redundant innate sensor systems that detect and ... Dual Role of DNA in Regulating ATP Hydrolysis by the SopA Partition Protein [作者：Ah-Seng, Y; Lopez, F; Pasta, F; Lane, D; Bouet, JY,期刊：Journal of Biological Chemistry, 页码：30067-30075 , 文章类型： Article，,卷期：2009年284-44] In bacteria, mitotic stability of plasmids and many chromosomes depends on replicon-specific systems, which comprise a centromere, a centromere-binding protein and an ATPase. Dynamic self-assembly of the ATPase appears t...