- PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation
[作者：Suzuki, E; Imoto, I; Pimkhaokham, A; Nakagawa, T; Kamata, N; Kozaki, K; Amagasa, T; Inazawa, J,期刊：Oncogene, 页码：7921-7932 , 文章类型： Article，,卷期：2007年26-57]
- Array-based comparative genomic hybridization (array-CGH) has good potential for the high-throughput identification of genetic aberrations in cell genomes. In the course of a program to screen a panel of oral squamous-ce...
- Differential mitotic degradation of the CDC25B phosphatase variants
[作者：Kieffer, I; Lorenzo, C; Dozier, C; Schmitt, E; Ducommun, B,期刊：Oncogene, 页码：7847-7858 , 文章类型： Article，,卷期：2007年26-57]
- CDC25 phosphatases control cell-cycle progression by dephosphorylating and activating cyclin-dependent kinases. CDC25B, one of the three members of this family in human cells, is thought to regulate initial mitotic event...
- Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial-mesenchymal transition
[作者：Lien, HC; Hsiao, YH; Lin, YS; Yao, YT; Juan, HF; Kuo, WH; Hung, MC; Chang, KJ; Hsieh, FJ,期刊：Oncogene, 页码：7859-7871 , 文章类型： Article，,卷期：2007年26-57]
- Metaplastic carcinoma of the breast (MCB) is a poorly understood subtype of breast cancer. It is generally characterized by the coexistence of ductal carcinomatous and transdifferentiated sarcomatous components, but the ...
- Gene expression and the biological phenotype of papillary thyroid carcinomas
[作者：Delys, L; Detours, V; Franc, B; Thomas, G; Bogdanova, T; Tronko, M; Libert, F; Dumont, JE; Maenhaut, C,期刊：Oncogene, 页码：7894-7903 , 文章类型： Article，,卷期：2007年26-57]
- The purpose of this paper is to correlate the molecular phenotype of papillary thyroid carcinoma (PTC) to their biological pathology. We hybridized 26 PTC on microarrays and showed that nearly 44% of the transcriptome wa...
- Sphingosine kinase-1 mediates BCR/ABL-induced upregulation of Mcl-1 in chronic myeloid leukemia cells
[作者：Li, QF; Huang, WR; Duan, HF; Wang, H; Wu, CT; Wang, LS,期刊：Oncogene, 页码：7904-7908 , 文章类型： Article，,卷期：2007年26-57]
- The signaling mechanisms responsible for BCR/ABL-induced regulation of Mcl-1 expression in chronic myelogenous leukemia (CML) cells remain unclear. In this study, we show that BCR/ABL could upregulate sphingosine kinase-...
- The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity
[作者：Anastasi, S; Baietti, MF; Frosi, Y; Alema, S; Segatto, O,期刊：Oncogene, 页码：7833-7846 , 文章类型： Article，,卷期：2007年26-57]
- Physiological signalling by the epidermal growth factor receptor ( EGFR) controls developmental processes and tissue homeostasis, whereas aberrant EGFR activity drives oncogenic cell transformation. Under normal conditio...
- Estrogen-induced and TAFII30-mediated gene repression by direct recruitment of the estrogen receptor and co-repressors to the core promoter and its reversal by tamoxifen
[作者：Hao, H; d'Alincourt-Salazar, M; Kelley, KMM; Shatnawi, A; Mukherjee, S; Shah, YM; Ratnam, M,期刊：Oncogene, 页码：7872-7884 , 文章类型： Article，,卷期：2007年26-57]
- Estradiol (E-2) acts through the estrogen receptor ( ER) to downregulate many genes, and tamoxifen (Tam) largely reverses this repression but the underlying mechanisms are unclear. Repression of the folate receptor (FR)-...
- Genetic analysis of p53 nuclear importation
[作者：Li, Q; Falsey, RR; Gaitonde, S; Sotello, V; Kislin, K; Martinez, JD,期刊：Oncogene, 页码：7885-7893 , 文章类型： Article，,卷期：2007年26-57]
- A key step in activation of the p53 tumor suppressor is its transport into the nucleus; however, despite intensive study of p53, the regulation of its subcellular localization is still poorly understood. Here we examined...
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