- Lhx2 links the intrinsic and extrinsic factors that control optic cup formation
[作者：Yun, S; Saijoh, Y; Hirokawa, KE; Kopinke, D; Murtaugh, LC; Monuki, ES; Levine, EM,期刊：Development, 页码：3895-3906 , 文章类型： Article，,卷期：2009年136-23]
- A crucial step in eye organogenesis is the transition of the optic vesicle into the optic cup. Several transcription factors and extracellular signals mediate this transition, but whether a single factor links them into ...
- Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos
[作者：Oki, S; Kitajima, K; Marques, S; Belo, JA; Yokoyama, T; Hamada, H; Meno, C,期刊：Development, 页码：3917-3925 , 文章类型： Article，,卷期：2009年136-23]
- The node at the anterior tip of the primitive streak serves as an initial generator of the left-right (L-R) axis in mammalian embryos. We now show that a small disturbance in molecular signaling at the node is responsibl...
- The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1
[作者：Agrawal, R; Tran, U; Wessely, O,期刊：Development, 页码：3927-3936 , 文章类型： Article，,卷期：2009年136-23]
- MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression at the post-transcriptional level. They are involved in diverse biological processes, such as development, differentiation, cell prolife...
- Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development
[作者：Seifert, AW; Bouldin, CM; Choi, KS; Harfe, BD; Cohn, MJ,期刊：Development, 页码：3949-3957 , 文章类型： Article，,卷期：2009年136-23]
- Malformations of the external genitalia are among the most common congenital anomalies in humans. The urogenital and anorectal sinuses develop from the embryonic cloaca, and the penis and clitoris develop from the genita...
- Temporal and spatial dissection of Shh signaling in genital tubercle development
[作者：Lin, CX; Yin, Y; Veith, GM; Fisher, AV; Long, FX; Ma, L,期刊：Development, 页码：3959-3967 , 文章类型： Article，,卷期：2009年136-23]
- Genital tubercle (GT) initiation and outgrowth involve coordinated morphogenesis of surface ectoderm, cloacal mesoderm and hindgut endoderm. GT development appears to mirror that of the limb. Although Shh is essential fo...
- Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program
[作者：Miyagawa, S; Moon, A; Haraguchi, R; Inoue, C; Harada, M; Nakahara, C; Suzuki, K; Matsumaru, D; Kaneko, T; Matsuo, I; Yang, L; Taketo, MM; Iguchi, T; Evans, SM; Yamada, G,期刊：Development, 页码：3969-3978 , 文章类型： Article，,卷期：2009年136-23]
- Embryonic appendicular structures, such as the limb buds and the developing external genitalia, are suitable models with which to analyze the reciprocal interactions of growth factors in the regulation of outgrowth. Alth...
- Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development
[作者：Reidy, KJ; Villegas, G; Teichman, J; Veron, D; Shen, W; Jimenez, J; Thomas, D; Tufro, A,期刊：Development, 页码：3979-3989 , 文章类型： Article，,卷期：2009年136-23]
- Semaphorin3a (Sema3a), a chemorepellant guidance protein, plays crucial roles in neural, cardiac and peripheral vascular patterning. Sema3a is expressed in the developing nephron, mature podocytes and collecting tubules....
- Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries
[作者：Hogan, BM; Herpers, R; Witte, M; Helotera, H; Alitalo, K; Duckers, HJ; Schulte-Merker, S,期刊：Development, 页码：4001-4009 , 文章类型： Article，,卷期：2009年136-23]
- The development of arteries, veins and lymphatics from pre-existing vessels are intimately linked processes controlled by a number of well-studied reiteratively acting signalling pathways. To delineate the mechanisms gov...
- Conditional knockdown of Nanog induces apoptotic cell death in mouse migrating primordial germ cells
[作者：Yamaguchi, S; Kurimoto, K; Yabuta, Y; Sasaki, H; Nakatsuji, N; Saitou, M; Tada, T,期刊：Development, 页码：4011-4020 , 文章类型： Article，,卷期：2009年136-23]
- The pluripotency factor Nanog is expressed in peri-implantation embryos and primordial germ cells (PGCs). Nanog-deficient mouse embryos die soon after implantation. To explore the function of Nanog in germ cells, Nanog R...
- FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain
[作者：Jacquet, BV; Salinas-Mondragon, R; Liang, HX; Therit, B; Buie, JD; Dykstra, M; Campbell, K; Ostrowski, LE; Brody, SL; Ghashghaei, HT,期刊：Development, 页码：4021-4031 , 文章类型： Article，,卷期：2009年136-23]
- Neuronal specification occurs at the periventricular surface of the embryonic central nervous system. During early postnatal periods, radial glial cells in various ventricular zones of the brain differentiate into ependy...
- Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells
[作者：Li, XJ; Zhang, XQ; Johnson, MA; Wang, ZB; LaVaute, T; Zhang, SC,期刊：Development, 页码：4055-4063 , 文章类型： Article，,卷期：2009年136-23]
- The directed differentiation of forebrain neuronal types from human embryonic stem cells (hESCs) has not been achieved. Here, we show that hESCs differentiate to telencephalic progenitors with a predominantly dorsal iden...
- Regulation of lymphatic-blood vessel separation by endothelial Rac1
[作者：D'Amico, G; Jones, DT; Nye, E; Sapienza, K; Ramjuan, AR; Reynolds, LE; Robinson, SD; Kostourou, V; Martinez, D; Aubyn, D; Grose, R; Thomas, GJ; Spencer-Dene, B; Zicha, D; Davies, D; Tybulewicz, V; Hodivala-Dilke, KM,期刊：Development, 页码：4043-4053 , 文章类型： Article，,卷期：2009年136-23]
- Sprouting angiogenesis and lymphatic-blood vessel segregation both involve the migration of endothelial cells, but the precise migratory molecules that govern the decision of blood vascular endothelial cells to segregate...
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