- The transcriptional foundation of pluripotency
[作者:Chambers, I; Tomlinson, SR,期刊:Development, 页码:2311-2322 , 文章类型: Review,,卷期:2009年136-14]
- A fundamental goal in biology is to understand the molecular basis of cell identity. Pluripotent embryonic stem (ES) cell identity is governed by a set of transcription factors centred on the triumvirate of Oct4, Sox2 an...
- Suppression of the immune response potentiates tadpole tail regeneration during the refractory period
[作者:Fukazawa, T; Naora, Y; Kunieda, T; Kubo, T,期刊:Development, 页码:2323-2327 , 文章类型: Article,,卷期:2009年136-14]
- Regenerative ability varies depending on animal species and developmental stage, but the factors that determine this variability remain unclear. Although Xenopus laevis tadpole tails possess high regenerative ability, th...
- Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes
[作者:Zhuang, SF; Shao, HJ; Guo, FL; Trimble, R; Pearce, E; Abmayr, SM,期刊:Development, 页码:2335-2344 , 文章类型: Article,,卷期:2009年136-14]
- The Immunoglobulin superfamily (IgSF) proteins Neph1 and Nephrin are co-expressed within podocytes in the kidney glomerulus, where they localize to the slit diaphragm (SD) and contribute to filtration between blood and u...
- The Ecdysone receptor controls the post-critical weight switch to nutrition-independent differentiation in Drosophila wing imaginal discs
[作者:Mirth, CK; Truman, JW; Riddiford, LM,期刊:Development, 页码:2345-2353 , 文章类型: Article,,卷期:2009年136-14]
- In holometabolous insects, a species-specific size, known as critical weight, needs to be reached for metamorphosis to be initiated in the absence of further nutritional input. Previously, we found that reaching critical...
- Essential role of the TRIC-B channel in Ca2+ handling of alveolar epithelial cells and in perinatal lung maturation
[作者:Yamazaki, D; Komazaki, S; Nakanishi, H; Mishima, A; Nishi, M; Yazawa, M; Yamazaki, T; Taguchi, R; Takeshima, H,期刊:Development, 页码:2355-2361 , 文章类型: Article,,卷期:2009年136-14]
- TRIC channels function as monovalent cation-specific channels that mediate counter ion movements coupled with ryanodine receptor-mediated Ca2+ release from intracellular stores in muscle cells. Mammalian tissues differen...
- Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons
[作者:Jacobs, FMJ; van der Linden, AJA; Wang, YH; von Oerthel, L; Sul, HS; Burbach, JPH; Smidt, MP,期刊:Development, 页码:2363-2373 , 文章类型: Article,,卷期:2009年136-14]
- The orphan nuclear receptor Nurr1 is essential for the development of meso-diencephalic dopamine (mdDA) neurons and is required, together with the homeobox transcription factor Pitx3, for the expression of genes involved...
- Differential and overlapping functions of two closely related Drosophila FGF8-like growth factors in mesoderm development
[作者:Klingseisen, A; Clark, IBN; Gryzik, T; Muller, HAJ,期刊:Development, 页码:2393-2402 , 文章类型: Article,,卷期:2009年136-14]
- Thisbe (Ths) and Pyramus (Pyr), two closely related Drosophila homologues of the vertebrate fibroblast growth factor (FGF) 8/17/18 subfamily, are ligands for the FGF receptor Heartless (Htl). Both ligands are required fo...
- Cell rearrangements, cell divisions and cell death in a migrating epithelial sheet in the abdomen of Drosophila
[作者:Bischoff, M; Cseresnyes, Z,期刊:Development, 页码:2403-2411 , 文章类型: Article,,卷期:2009年136-14]
- During morphogenesis, cell movements, cell divisions and cell death work together to form complex patterns and to shape organs. These events are the outcome of decisions made by many individual cells, but how these decis...
- The RNA-binding protein Mex3b has a fine-tuning system for mRNA regulation in early Xenopus development
[作者:Takada, H; Kawana, T; Ito, Y; Kikuno, RF; Mamada, H; Araki, T; Koga, H; Asashima, M; Taira, M,期刊:Development, 页码:2413-2422 , 文章类型: Article,,卷期:2009年136-14]
- Post-transcriptional control by RNA-binding proteins is a precise way to assure appropriate levels of gene expression. Here, we identify a novel mRNA regulatory system involving Mex3b (RKHD3) and demonstrate its role in ...
- Regulation of stem cell maintenance by the Polycomb protein FIE has been conserved during land plant evolution
[作者:Mosquna, A; Katz, A; Decker, EL; Rensing, SA; Reski, R; Ohad, N,期刊:Development, 页码:2433-2444 , 文章类型: Article,,卷期:2009年136-14]
- The Polycomb group (PcG) complex is involved in the epigenetic control of gene expression profiles. In flowering plants, PcG proteins regulate vegetative and reproductive programs. Epigenetically inherited states establi...
- C-elegans Rab GTPase activating protein TBC-2 promotes cell corpse degradation by regulating the small GTPase RAB-5
[作者:Li, WD; Zou, W; Zhao, DF; Yan, JC; Zhu, ZY; Lu, J; Wang, XC,期刊:Development, 页码:2445-2455 , 文章类型: Article,,卷期:2009年136-14]
- During apoptosis, dying cells are quickly internalized by neighboring cells or phagocytes, and are enclosed in phagosomes that undergo a maturation process to generate the phagoslysosome, in which cell corpses are eventu...
- FGF signaling is strictly required to maintain early telencephalic precursor cell survival
[作者:Paek, H; Gutin, G; Hebert, JM,期刊:Development, 页码:2457-2465 , 文章类型: Article,,卷期:2009年136-14]
- The FGF family of extracellular signaling factors has been proposed to play multiple roles in patterning the telencephalon, the precursor to the cerebrum. In this study, unlike previous ones, we effectively abolish FGF s...
- Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling
[作者:North, HA; Zhao, XM; Kolk, SM; Clifford, MA; Ziskind, DM; Donoghue, MJ,期刊:Development, 页码:2467-2476 , 文章类型: Article,,卷期:2009年136-14]
- Eph receptors are widely expressed during cerebral cortical development, yet a role for Eph signaling in the generation of cells during corticogenesis has not been shown. Cortical progenitor cells selectively express one...
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