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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共20条记录   Cross Talk between Immunoglobulin Heavy-Chain Transcription and RNA Surveillance during B Cell Development [作者：Tinguely, A; Chemin, G; Peron, S; Sirac, C; Reynaud, S; Cogne, M; Delpy, L,期刊：Molecular and Cellular Biology, 页码：107-117 , 文章类型： Article，,卷期：2012年32-1] Immunoglobulin (Ig) genes naturally acquire frequent premature termination codons during the error-prone V(D)J recombination process. Although B cell differentiation is linked to the expression of productive Ig alleles, ... Two-Step Engulfment of Apoptotic Cells [作者：Toda, S; Hanayama, R; Nagata, S,期刊：Molecular and Cellular Biology, 页码：118-125 , 文章类型： Article，,卷期：2012年32-1] Apoptotic cells expose phosphatidylserine on their surface as an "eat me" signal, and macrophages respond by engulfing them. Although several molecules that specifically bind phosphatidylserine have been identified, the ... Architecture of the Yeast RNA Polymerase II Open Complex and Regulation of Activity by TFIIF [作者：Fishburn, J; Hahn, S,期刊：Molecular and Cellular Biology, 页码：12-25 , 文章类型： Article，,卷期：2012年32-1] To investigate the function and architecture of the open complex state of RNA polymerase II (Pol II), Saccharomyces cerevisiae minimal open complexes were assembled by using a series of heteroduplex HIS4 promoters, TATA ... A Role for SMN Exon 7 Splicing in the Selective Vulnerability of Motor Neurons in Spinal Muscular Atrophy [作者：Ruggiu, M; McGovern, VL; Lotti, F; Saieva, L; Li, DK; Kariya, S; Monani, UR; Burghes, AHM; Pellizzoni, L,期刊：Molecular and Cellular Biology, 页码：126-138 , 文章类型： Article，,卷期：2012年32-1] Spinal muscular atrophy (SMA) is an inherited motor neuron disease caused by homozygous loss of the Survival Motor Neuron 1 (SMN1) gene. In the absence of SMN1, inefficient inclusion of exon 7 in transcripts from the nea... Localization of HET-S to the Cell Periphery, Not to [Het-s] Aggregates, Is Associated with [Het-s]-HET-S Toxicity [作者：Mathur, V; Seuring, C; Riek, R; Saupe, SJ; Liebman, SW,期刊：Molecular and Cellular Biology, 页码：139-153 , 文章类型： Article，,卷期：2012年32-1] Prion diseases are associated with accumulation of the amyloid form of the prion protein, but the mechanisms of toxicity are unknown. Amyloid toxicity is also associated with fungal prions. In Podospora anserina, the sim... Histone H3 Lysine 56 Acetylation and the Response to DNA Replication Fork Damage [作者：Wurtele, H; Kaiser, GS; Bacal, J; St-Hilaire, E; Lee, EH; Tsao, S; Dorn, J; Maddox, P; Lisby, M; Pasero, P; Verreault, A,期刊：Molecular and Cellular Biology, 页码：154-172 , 文章类型： Article，,卷期：2012年32-1] In Saccharomyces cerevisiae, histone H3 lysine 56 acetylation (H3K56ac) occurs in newly synthesized histones that are deposited throughout the genome during DNA replication. Defects in H3K56ac sensitize cells to genotoxi... Mink1 Regulates beta-Catenin-Independent Wnt Signaling via Prickle Phosphorylation [作者：Daulat, AM; Luu, O; Sing, A; Zhang, L; Wrana, JL; McNeill, H; Winklbauer, R; Angers, S,期刊：Molecular and Cellular Biology, 页码：173-185 , 文章类型： Article，,卷期：2012年32-1] beta-Catenin-independent Wnt signaling pathways have been implicated in the regulation of planar cell polarity (PCP) and convergent extension (CE) cell movements. Prickle, one of the core proteins of these pathways, is k... Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70 [作者：Yu, EY; Sun, J; Lei, M; Lue, NF,期刊：Molecular and Cellular Biology, 页码：186-198 , 文章类型： Article，,卷期：2012年32-1] The budding yeast Cdc13-Stn1-Ten1 complex is crucial for telomere protection and has been proposed to resemble the RPA complex structurally and functionally. The Cdc13 homologues in Candida species are unusually small an... Essential Function of Protein 4.1G in Targeting of Membrane Protein Palmitoylated 6 into Schmidt-Lanterman Incisures in Myelinated Nerves [作者：Terada, N; Saitoh, Y; Ohno, N; Komada, M; Saitoh, S; Peles, E; Ohno, S,期刊：Molecular and Cellular Biology, 页码：199-205 , 文章类型： Article，,卷期：2012年32-1] Protein 4.1G is a membrane skeletal protein found in specific subcellular structures in myelinated Schwann cells and seminiferous tubules. Here, we show that in the mouse sciatic nerve, protein 4.1G colocalized at Schmid... Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks [作者：Alers, S; Loffler, AS; Wesselborg, S; Stork, B,期刊：Molecular and Cellular Biology, 页码：2-11 , 文章类型： Review，,卷期：2012年32-1] Living cells are adaptive self-sustaining systems. They strictly depend on the sufficient supply of oxygen, energy, and nutrients from the outside in order to sustain their internal organization. However, as autonomous e... Notch Signaling in Sertoli Cells Regulates Cyclical Gene Expression of Hes1 but Is Dispensable for Mouse Spermatogenesis [作者：Hasegawa, K; Okamura, Y; Saga, Y,期刊：Molecular and Cellular Biology, 页码：206-215 , 文章类型： Article，,卷期：2012年32-1] Mammalian spermatogenesis is a highly regulated system dedicated to the continuous production of spermatozoa from spermatogonial stem cells, and the process largely depends on microenvironments created by Sertoli cells, ... The Small Heat Shock Protein ODF1/HSPB10 Is Essential for Tight Linkage of Sperm Head to Tail and Male Fertility in Mice [作者：Yang, KF; Meinhardt, A; Zhang, B; Grzmil, P; Adham, IM; Hoyer-Fender, S,期刊：Molecular and Cellular Biology, 页码：216-225 , 文章类型： Article，,卷期：2012年32-1] Sperm motility and hence male fertility strictly depends on proper development of the sperm tail and its tight anchorage to the head. The main protein of sperm tail outer dense fibers, ODF1/HSPB10, belongs to the family ... Autophagy Driven by a Master Regulator of Hematopoiesis [作者：Kang, YA; Sanalkumar, R; O'Geen, H; Linnemann, AK; Chang, CJ; Bouhassira, EE; Farnham, PJ; Keles, S; Bresnick, EH,期刊：Molecular and Cellular Biology, 页码：226-239 , 文章类型： Article，,卷期：2012年32-1] Developmental and homeostatic remodeling of cellular organelles is mediated by a complex process termed autophagy. The cohort of proteins that constitute the autophagy machinery functions in a multistep biochemical pathw... Orphan Nuclear Receptor PNR/NR2E3 Stimulates p53 Functions by Enhancing p53 Acetylation [作者：Wen, Z; Pyeon, D; Wang, YD; Lambert, P; Xu, W; Ahlquist, P,期刊：Molecular and Cellular Biology, 页码：26-35 , 文章类型： Article，,卷期：2012年32-1] Since inactivation of tumor suppressor p53 functions is one of the most common features of human cancer cells, restoring p53 expression and activity is an important focus in cancer therapy. Here we report identification ... O(2) Regulates Skeletal Muscle Progenitor Differentiation through Phosphatidylinositol 3-Kinase/AKT Signaling [作者：Majmundar, AJ; Skuli, N; Mesquita, RC; Kim, MN; Yodh, AG; Nguyen-McCarty, M; Simon, MC,期刊：Molecular and Cellular Biology, 页码：36-49 , 文章类型： Article，,卷期：2012年32-1] Skeletal muscle stem/progenitor cells, which give rise to terminally differentiated muscle, represent potential therapies for skeletal muscle diseases. Delineating the factors regulating these precursors will facilitate ... TIEG1 Inhibits Breast Cancer Invasion and Metastasis by Inhibition of Epidermal Growth Factor Receptor (EGFR) Transcription and the EGFR Signaling Pathway [作者：Jin, W; Chen, BB; Li, JY; Zhu, H; Huang, M; Gu, SM; Wang, QQ; Chen, JY; Yu, SJ; Wu, J; Shao, ZM,期刊：Molecular and Cellular Biology, 页码：50-63 , 文章类型： Article，,卷期：2012年32-1] TIEG1 can induce apoptosis of cancer cells, but its role in inhibiting invasion and metastasis has not been reported and is unclear. In this study, we find that decreased TIEG1 expression is associated with increased hum...