- Kepler Detected Gravity-Mode Period Spacings in a Red Giant Star
[作者:Beck, PG; Bedding, TR; Mosser, B; Stello, D; Garcia, RA; Kallinger, T; Hekker, S; Elsworth, Y; Frandsen, S; Carrier, F; De Ridder, J; Aerts, C; White, TR; Huber, D; Dupret, MA; Montalban, J; Miglio, A; Noels, A; Chaplin, WJ; Kjeldsen, H; Christensen-Dalsg,期刊:Science, 页码:205-205 , 文章类型: Article,,卷期:2011年332-6026]
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- Ribozyme-Catalyzed Transcription of an Active Ribozyme
[作者:Wochner, A; Attwater, J; Coulson, A; Holliger, P,期刊:Science, 页码:209-212 , 文章类型: Article,,卷期:2011年332-6026]
- A critical event in the origin of life is thought to have been the emergence of an RNA molecule capable of replicating a primordial RNA "genome." Here we describe the evolution and engineering of an RNA polymerase ribozy...
- Ensemble Asteroseismology of Solar-Type Stars with the NASA Kepler Mission
[作者:Chaplin, WJ; Kjeldsen, H; Christensen-Dalsgaard, J; Basu, S; Miglio, A; Appourchaux, T; Bedding, TR; Elsworth, Y; Garcia, RA; Gilliland, RL; Girardi, L; Houdek, G; Karoff, C; Kawaler, SD; Metcalfe, TS; Molenda-Zakowicz, J; Monteiro, MJPFG; Thompson, MJ; V,期刊:Science, 页码:213-216 , 文章类型: Article,,卷期:2011年332-6026]
- In addition to its search for extrasolar planets, the NASA Kepler mission provides exquisite data on stellar oscillations. We report the detections of oscillations in 500 solar-type stars in the Kepler field of view, an ...
- HD 181068: A Red Giant in a Triply Eclipsing Compact Hierarchical Triple System
[作者:Derekas, A; Kiss, LL; Borkovits, T; Huber, D; Lehmann, H; Southworth, J; Bedding, TR; Balam, D; Hartmann, M; Hrudkova, M; Ireland, MJ; Kovacs, J; Mezo, G; Moor, A; Niemczura, E; Sarty, GE; Szabo, GM; Szabo, R; Telting, JH; Tkachenko, A; Uytterhoeven, K; B,期刊:Science, 页码:216-218 , 文章类型: Article,,卷期:2011年332-6026]
- Hierarchical triple systems comprise a close binary and a more distant component. They are important for testing theories of star formation and of stellar evolution in the presence of nearby companions. We obtained 218 d...
- C-13 NMR Guides Rational Design of Nanocatalysts via Chemisorption Evaluation in Liquid Phase
[作者:Tedsree, K; Chan, CWA; Jones, S; Cuan, QA; Li, WK; Gong, XQ; Tsang, SCE,期刊:Science, 页码:224-228 , 文章类型: Article,,卷期:2011年332-6026]
- The search for more efficient heterogeneous catalysts remains critical to the chemical industry. The Sabatier principle of maximizing catalytic activity by optimizing the adsorption energy of the substrate molecule could...
- Oriented 2D Covalent Organic Framework Thin Films on Single-Layer Graphene
[作者:Colson, JW; Woll, AR; Mukherjee, A; Levendorf, MP; Spitler, EL; Shields, VB; Spencer, MG; Park, J; Dichtel, WR,期刊:Science, 页码:228-231 , 文章类型: Article,,卷期:2011年332-6026]
- Covalent organic frameworks (COFs), in which molecular building blocks form robust microporous networks, are usually synthesized as insoluble and unprocessable powders. We have grown two-dimensional (2D) COF films on sin...
- A Virophage at the Origin of Large DNA Transposons
[作者:Fischer, MG; Suttle, CA,期刊:Science, 页码:231-234 , 文章类型: Article,,卷期:2011年332-6026]
- DNA transposons are mobile genetic elements that have shaped the genomes of eukaryotes for millions of years, yet their origins remain obscure. We discovered a virophage that, on the basis of genetic homology, likely rep...
- A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis
[作者:Bhabha, G; Lee, J; Ekiert, DC; Gam, J; Wilson, IA; Dyson, HJ; Benkovic, SJ; Wright, PE,期刊:Science, 页码:234-238 , 文章类型: Article,,卷期:2011年332-6026]
- Conformational dynamics play a key role in enzyme catalysis. Although protein motions have clear implications for ligand flux, a role for dynamics in the chemical step of enzyme catalysis has not been clearly established...
- Mutations in U4atac snRNA, a Component of the Minor Spliceosome, in the Developmental Disorder MOPD I
[作者:He, HL; Liyanarachchi, S; Akagi, K; Nagy, R; Li, JF; Dietrich, RC; Li, W; Sebastian, N; Wen, B; Xin, BZ; Singh, J; Yan, P; Alder, H; Haan, E; Wieczorek, D; Albrecht, B; Puffenberger, E; Wang, H; Westman, JA; Padgett, RA; Symer, DE; de la Chapelle, A,期刊:Science, 页码:238-240 , 文章类型: Article,,卷期:2011年332-6026]
- Small nuclear RNAs (snRNAs) are essential factors in messenger RNA splicing. By means of homozygosity mapping and deep sequencing, we show that a gene encoding U4atac snRNA, a component of the minor U12-dependent spliceo...
- Association of TALS Developmental Disorder with Defect in Minor Splicing Component U4atac snRNA
[作者:Edery, P; Marcaillou, C; Sahbatou, M; Labalme, A; Chastang, J; Touraine, R; Tubacher, E; Senni, F; Bober, MB; Nampoothiri, S; Jouk, PS; Steichen, E; Berland, S; Toutain, A; Wise, CA; Sanlaville, D; Rousseau, F; Clerget-Darpoux, F; Leutenegger, AL,期刊:Science, 页码:240-243 , 文章类型: Article,,卷期:2011年332-6026]
- The spliceosome, a ribonucleoprotein complex that includes proteins and small nuclear RNAs (snRNAs), catalyzes RNA splicing through intron excision and exon ligation to produce mature messenger RNAs, which, in turn serve...
- Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis
[作者:Wu, D; Molofsky, AB; Liang, HE; Ricardo-Gonzalez, RR; Jouihan, HA; Bando, JK; Chawla, A; Locksley, RM,期刊:Science, 页码:243-247 , 文章类型: Article,,卷期:2011年332-6026]
- Eosinophils are associated with helminth immunity and allergy, often in conjunction with alternatively activated macrophages (AAMs). Adipose tissue AAMs are necessary to maintain glucose homeostasis and are induced by th...
- AMP-Activated Protein Kinase Regulates Neuronal Polarization by Interfering with PI 3-Kinase Localization
[作者:Amato, S; Liu, XX; Zheng, B; Cantley, L; Rakic, P; Man, HY,期刊:Science, 页码:247-251 , 文章类型: Article,,卷期:2011年332-6026]
- Axon-dendrite polarization is crucial for neural network wiring and information processing in the brain. Polarization begins with the transformation of a single neurite into an axon and its subsequent rapid extension, wh...
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