- hGPR87 contributes to viability of human tumor cells
[作者:Glatt, S; Halbauer, D; Heindil, S; Wernitznig, A; Kozinal, D; Su, KC; Puri, C; Garin-Chesa, P; Sommergruber, WG,期刊:International Journal of Cancer, 页码:2008-2016 , 文章类型: Article,,卷期:2008年122-9]
- Emerging in vitro and in vivo data underline the crucial role of G-protein-coupled receptors (GPCRs) in tumorigenesis. Here, we report the contribution of hGPR87, a predicted member of the P2Y subfamily of GPCRs, to prol...
- International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers
[作者:Metcalfe, KA; Birenbaum-Carmeli, D; Lubinski, J; Gronwald, J; Lynch, H; Moller, P; Ghadirian, P; Foulkes, WD; Klijn, J; Friedman, E; Kim-Sing, C; Ainsworth, P; Rosen, B; Domchek, S; Wagner, T; Tung, N; Manoukian, S; Couch, F; Sun, P; Narod, SA,期刊:International Journal of Cancer, 页码:2017-2022 , 文章类型: Article,,卷期:2008年122-9]
- Several options for cancer prevention are available for, women with a BRCA1 or BRCA2 mutation, including prophylactic surgery, chemoprevention and screening. The authors report on preventive practices in women with mutat...
- The possible role of factor H in colon cancer resistance to complement attack
[作者:Wilezek, E; Rzepko, R; Nowis, D; Legat, M; Golab, J; Glab, M; Gorlewicz, A; Konopacki, F; Mazurkiewicz, M; Sladowski, D; Gornicka, B; Wasiutynski, A; Wilczynski, GM,期刊:International Journal of Cancer, 页码:2030-2037 , 文章类型: Article,,卷期:2008年122-9]
- A soluble complement inhibitor factor H (FH) and its splice variant factor H-like protein (FHL) have been recently discovered to play a major role in malignant cell escape from complement-mediated cytotoxicity in lung-, ...
- PLAC1 is a tumor-specific antigen capable of eliciting spontaneous antibody responses in human cancer patients
[作者:Dong, XY; Peng, JR; Ye, YJ; Chen, HS; Zhan, LJ; Pang, XW; Li, Y; Zhang, Y; Wang, S; Fant, ME; Yin, YH; Chen, WF,期刊:International Journal of Cancer, 页码:2038-2043 , 文章类型: Article,,卷期:2008年122-9]
- Immunoselection and tumor evasion constitutes one of the major obstacles in cancer immunotherapy. A potential solution to this problem is the development of polyvalent vaccines, and the identification of more tumor-speci...
- Diagnostic targeting of colon cancer using a novel fluorescent somatostatin conjugate in a mouse xenograft model
[作者:Kostenich, G; Oron-Herman, M; Kimel, S; Livnah, N; Tsarfaty, I; Orenstein, A,期刊:International Journal of Cancer, 页码:2044-2049 , 文章类型: Article,,卷期:2008年122-9]
- Colorectal carcinoma is one of the more prevalent, highly malignant human tumors, occurring in about 7% of the population. However, if diagnosed and treated in its early stages, colon cancer is curable. In our study, we ...
- Prognostic significance of MMP-9 and TIMP-1 serum and tissue expression in breast cancer
[作者:Wu, ZS; Wu, Q; Yang, JH; Wang, HQ; Ding, XD; Yang, F; Xu, XC,期刊:International Journal of Cancer, 页码:2050-2056 , 文章类型: Article,,卷期:2008年122-9]
- Tumor progression and metastasis contribute to the great majority of breast cancer deaths. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) are thought to be involved in tumor progress...
- Plasma vitamin B12 concentrations and the risk of colorectal cancer: A nested case-referent study
[作者:Dahlin, AM; Van Guelpen, B; Hultdin, J; Johansson, I; Hallmans, G; Palmqvist, R,期刊:International Journal of Cancer, 页码:2057-2061 , 文章类型: Article,,卷期:2008年122-9]
- In this nested case-referent study, we related plasma concentrations of vitamin B12 to the risk of colorectal cancer, taking into consideration prediagnostic plasma folate and total homocysteine concentrations. Subjects ...
- Non-Hodgkin lymphoma and obesity: A pooled analysis from the InterLymph consortium
[作者:Willett, EV; Morton, LM; Hartge, P; Becker, N; Bernstein, L; Boffetta, P; Bracci, P; Cerhan, J; Chiu, BCH; Cocco, P; Dal Maso, L; Davis, S; De Sanjose, S; Smedby, KE; Ennas, MG; Foretova, L; Holiy, EA; La Vecchia, C; Matsuo, K; Maynadie, M; Melbye, M; Negri, E; Nieters, A; Severson, R; Slager, SL; Spinelli, JJ; Staines, A; Talamini, R; Vornanen, M; Weisenburger, DD; Roman, E,期刊:International Journal of Cancer, 页码:2062-2070 , 文章类型: Article,,卷期:2008年122-9]
- Nutritional status is known to alter immune function, a suspected risk factor for non-Hodgkin lymphoma (NHL). To investigate whether long-term over, or under, nutrition is associated with NHL, self-reported anthropometri...
- Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis
[作者:Gregory-Bass, RC; Olatinwo, M; Xu, W; Matthews, R; Stiles, JK; Thomas, K; Liu, D; Tsang, B; Thompson, WE,期刊:International Journal of Cancer, 页码:1923-1930 , 文章类型: Article,,卷期:2008年122-9]
- Current approaches to the treatment of ovarian cancer are limited because of the development of resistance to chemotherapy. Prohibitin (Phb1) is a possible candidate protein that contributes to development of drug resist...
- 17 beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer
[作者:Day, JM; Foster, PA; Tutill, HJ; Parsons, MFC; Newman, SP; Chander, SK; Allan, GM; Lawrence, HR; Vicker, N; Potter, BVL; Reed, MJ; Purohit, A,期刊:International Journal of Cancer, 页码:1931-1940 , 文章类型: Article,,卷期:2008年122-9]
- Oestradiol (E2) stimulates the growth of hormone-dependent breast cancer. 17 beta-hydroxysteroid dehydrogenases (17 beta-HSDs) catalyse the pre-receptor activation/inactivation of hormones and other substrates. 17 beta-H...
- Evidence of a novel docetaxel sensitizer, garlic-derived S-allylmercaptocysteine, as a treatment option for hormone refractory prostate cancer
[作者:Howard, EW; Lee, DT; Chin, YT; Chua, CW; Wang, X; Wong, YC,期刊:International Journal of Cancer, 页码:1941-1948 , 文章类型: Article,,卷期:2008年122-9]
- The recent introduction of docetaxel in the treatment of hormone refractory prostate cancer (HRPC) has made a small but significant impact on patient survival. However, its effect is limited by intolerance and resistance...
- The molecular etiology of breast cancer: Evidence from biomarkers of risk
[作者:Gaikwad, NW; Yang, L; Muti, P; Meza, JL; Pruthi, S; Ingle, JN; Rogan, EG; Cavalieri, EL,期刊:International Journal of Cancer, 页码:1949-1957 , 文章类型: Article,,卷期:2008年122-9]
- Estrogens can become endogenous carcinogens via formation of catechol estrogen quinones, which react with DNA to form specific depurinating estrogen-DNA adducts. The mutations resulting from these adducts can lead to cel...
- Tumorigenicity and genotoxicity of an environmental pollutant 2,7-dinitrofluorene after systemic administration at a low dose level to female rats
[作者:Malejka-Giganti, D; Parkin, DR; Decker, RW; Niehans, GA; Bliss, RL; Churchwell, MI; Beland, FA,期刊:International Journal of Cancer, 页码:1958-1965 , 文章类型: Article,,卷期:2008年122-9]
- Environmental pollution with nitroaromatic compounds may pose health hazards. We have examined the tumorigenicity in female Sprague-Dawley rats of 2,7-dinitrofluorene (2,7-diNF) and 9-oxo-2,7-diNF administered by intrape...
- The combination of epigallocatechin gallate and curcumin suppresses ER alpha-breast cancer cell growth in vitro and in vivo
[作者:Somers-Edgar, TJ; Scandlyn, MJ; Stuart, EC; Le Nedelec, MJ; Valentine, SP; Rosengren, RJ,期刊:International Journal of Cancer, 页码:1966-1971 , 文章类型: Article,,卷期:2008年122-9]
- Both epigallocatechin gallate (EGCG) and curcumin have shown efficacy in various in vivo and in vitro models of cancer. This study was designed to determine the efficacy of these naturally derived polyphenolic compounds ...
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