- Global analysis of metastasis-associated gene expression in primary cultures from clinical specimens of clear-cell renal-cell carcinoma
[作者:Tan, XJ; Zhai, YJ; Chang, WJ; Hou, JG; He, SQ; Lin, LP; Yu, YW; Xu, DF; Xiao, JR; Ma, LY; Wang, GP; Cao, TH; Cao, GW,期刊:International Journal of Cancer, 页码:1080-1088 , 文章类型: Article,,卷期:2008年123-5]
- Metastatic clear-cell renal-cell carcinoma (ccRCC) has a poor prognosis and unpredictable course, and there are no molecular markers that reliably predict ccRCC metastasis. In this study, ccRCC specimens from 84 patients...
- Chlamydophila psittaci is viable and infectious in the conjunctiva and peripheral blood of patients with ocular adnexal lymphoma: Results of a single-center prospective case-control study
[作者:Ferreri, AJM; Dolcetti, R; Dognini, GP; Malabarba, L; Vicari, N; Pasini, E; Ponzoni, M; Cangi, MG; Pecciarini, L; Resti, AG; Doglioni, C; Rossini, S; Magnino, S,期刊:International Journal of Cancer, 页码:1089-1093 , 文章类型: Article,,卷期:2008年123-5]
- Ocular adnexal MALT lymphoma (OAML) is linked to Chlamydophila psittaci (Cp) infection. Viability and infectivity of Cp, demonstrated by growth in culture, has not been yet investigated in these patients. We conducted a ...
- Breast cancer and microbial cancer incidence in female populations around the world: A surprising hyperbolic association
[作者:Savu, A; Potter, J; Li, SW; Yasui, Y,期刊:International Journal of Cancer, 页码:1094-1099 , 文章类型: Article,,卷期:2008年123-5]
- Current literature on cancer epidemiology typically discusses etiology of cancer by cancer type. Risks of different cancer types are, however, correlated at population level and may provide etiological clues. We showed p...
- Spontaneous T cell responses to Epstein-Barr virus-encoded BARF1 protein and derived peptides in patients with nasopharyngeal carcinoma: Bases for improved immunotherapy
[作者:Martorelli, D; Houali, K; Caggiari, L; Vaccher, E; Barzan, L; Franchin, G; Gloghini, A; Pavan, A; Da Ponte, A; Tedeschi, RM; De Re, V; Carbone, A; Ooka, T; De Paoli, P; Dolcetti, R,期刊:International Journal of Cancer, 页码:1100-1107 , 文章类型: Article,,卷期:2008年123-5]
- Immunotherapy approaches targeting Epstein-Barr virus (EBV)encoded antigens induce objective clinical responses only in a fraction of patients with undifferentiated nasopharyngeal carcinoma (UNPC). In the present study, ...
- Arginase 2 is expressed by human lung cancer, but it neither induces immune suppression, nor affects disease progression
[作者:Rotondo, R; Mastracci, L; Piazza, T; Barisione, G; Fabbi, M; Cassanello, M; Costa, R; Morandi, B; Astigiano, S; Cesario, A; Sormani, MP; Ferlazzo, G; Grossi, F; Ratto, GB; Ferrini, S; Frumento, G,期刊:International Journal of Cancer, 页码:1108-1116 , 文章类型: Article,,卷期:2008年123-5]
- In human prostate cancer, Arginase 2 (ARG2) and nitric oxide synthase (NOS) are concomitantly expressed by tumor cells, and induce tumor immune escape via peroxynitrite-dependent Tyrosine nitrosylation. Since there were ...
- The methylation status of RASSF1A promoter predicts responsiveness to chemotherapy and eventual cure in hepatoblastoma patients
[作者:Honda, S; Haruta, M; Sugawara, W; Sasaki, F; Ohira, M; Matsunaga, T; Yamaoka, H; Horie, H; Ohnuma, N; Nakagawara, A; Hiyama, E; Todo, S; Kaneko, Y,期刊:International Journal of Cancer, 页码:1117-1125 , 文章类型: Article,,卷期:2008年123-5]
- Despite the progress of therapy, outcomes of advanced hepatoblastoma patients who are refractory to standard preoperative chemotherapy remain unsatisfactory. To improve the mortality rate, novel prognostic markers are ne...
- The high affinity peroxisome proliferator-activated receptor-gamma agonist RS5444 inhibits both initiation and progression of colon tumors in azoxymethane-treated mice
[作者:Su, WD; Necela, BM; Fujiwara, K; Kurakata, S; Murray, NR; Fields, AP; Thompson, EA,期刊:International Journal of Cancer, 页码:991-997 , 文章类型: Article,,卷期:2008年123-5]
- We evaluated RS5444, a thiazolidinedione high affinity PPAR gamma agonist, for the ability to inhibit colon carcinogenesis in azoxymethane (AOM)-treated mice. In our initial experiment, mice were treated with RS5444 duri...
- CpG island methylator phenotype association with upregulated telomerase activity in hepatocellular carcinoma
[作者:Zhang, CS; Guo, XL; Jiang, GC; Zhang, L; Yang, Y; Shen, F; Wu, MC; Wei, LX,期刊:International Journal of Cancer, 页码:998-1004 , 文章类型: Article,,卷期:2008年123-5]
- CpG island methylator phenotype (CIMP) involves the targeting of multiple genes by promoter hypermethylation. Telomerase plays an important role in the development of cellular immortality and oncogenesis. To gain insight...
- Synergistic inhibition of head and neck tumor growth by green tea (-)-epigallocatechin-3-gallate and EGFR tyrosine kinase inhibitor
[作者:Zhang, X; Zhang, HZ; Tighiouart, M; Lee, JE; Shin, HJ; Khuri, FR; Yang, CS; Chen, Z; Shin, DM,期刊:International Journal of Cancer, 页码:1005-1014 , 文章类型: Article,,卷期:2008年123-5]
- One of the mechanisms of the antitumor activity of green tea (-)-epigallocatechin-3-gallate (EGCG) is associated with its effect on epidermal growth factor receptor (EGFR)-mediated signaling transduction pathways. We inv...
- Activation of PPAR alpha inhibits IGF-I-mediated growth and survival responses in medulloblastoma cell lines
[作者:Urbanska, K; Pannizzo, P; Grabacka, M; Croul, S; Del Valle, L; Khalili, K; Reiss, K,期刊:International Journal of Cancer, 页码:1015-1024 , 文章类型: Article,,卷期:2008年123-5]
- Recent studies suggest a potential role of lipid lowering drugs, fibrates and statins, in anticancer treatment. One candidate for tumor chemoprevention is fenofibrate, which is a potent agonist of peroxisome proliferator...
- Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: Growth inhibition by receptor activation
[作者:Gustafsson, K; Wang, X; Severa, D; Eriksson, M; Kimby, E; Merup, M; Christensson, B; Flygare, J; Sander, B,期刊:International Journal of Cancer, 页码:1025-1033 , 文章类型: Article,,卷期:2008年123-5]
- Endogenous and synthetic cannabinoids exert antiproliferative and proapoptotic effects in various types of cancer and in mantle cell lymphoma (MCL). In this study, we evaluated the expression of cannabinoid receptors typ...
- Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases
[作者:Bu, GJ; Lu, WY; Liu, CC; Selander, K; Yoneda, T; Hall, C; Keller, ET; Li, YH,期刊:International Journal of Cancer, 页码:1034-1042 , 文章类型: Article,,卷期:2008年123-5]
- Most breast cancer metastases in bone form osteolytic lesions, but the mechanisms of tumor-induced bone resorption and destruction are not fully understood. Although it is well recognized that Wnt/beta-catenin signaling ...
- Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma
[作者:Kawase, A; Ishii, G; Nagai, K; Ito, T; Nagano, T; Murata, Y; Hishida, T; Nishimura, M; Yoshida, J; Suzuki, K; Ochiai, A,期刊:International Journal of Cancer, 页码:1053-1059 , 文章类型: Article,,卷期:2008年123-5]
- Recent studies have reported increased podoplanin expression by cancer cells and stromal cells, but little is known about its expression and biological significance in adenocarcinoma of the lung. We examined podoplanin e...
- p73 isoforms affect VEGF, VEGF(165)b and PEDF expression in human colorectal tumors: VEGF(165)b downregulation as a marker of poor prognosis
[作者:Diaz, R; Pena, C; Silva, J; Lorenzo, Y; Garcia, V; Garcia, JM; Sanchez, A; Espinosa, P; Yuste, R; Bonilla, F; Dominguez, G,期刊:International Journal of Cancer, 页码:1060-1067 , 文章类型: Article,,卷期:2008年123-5]
- The secreted mitogen vascular endothelial growth factor, VEGF, plays a pivotal role in angiogenesis. Hypoxia, inactivation of p53 and oncogenic K-Ras induce VEGF expression. Other factors such as p73 may also affect VEGF...
- Ku70 predicts response and primary tumor recurrence after therapy in locally advanced head and neck cancer
[作者:Pavon, MA; Parreno, M; Leon, X; Sancho, FJ; Cespedes, MV; Casanova, I; Lopez-Pousa, A; Mangues, MA; Quer, M; Barnadas, A; Mangues, R,期刊:International Journal of Cancer, 页码:1068-1079 , 文章类型: Article,,卷期:2008年123-5]
- 5-Fluorouracil and cisplatin-based induction chemotherapy (IQ is commonly used to treat locally advanced head and neck squamous cell carcinoma (HNSCC). The role of nonhomologous end joining (NHEJ) genes (Ku70, Ku80 and D...
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