- Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion
[作者：Song, LY; Li, YH; Wang, K; Wang, YZ; Molotkov, A; Gao, LF; Zhao, TY; Yamagami, T; Wang, YP; Gan, QN; Pleasure, DE; Zhou, CJJ,期刊：Development, 页码：3161-3171 , 文章类型： Article，,卷期：2009年136-18]
- Neither the mechanisms that govern lip morphogenesis nor the cause of cleft lip are well understood. We report that genetic inactivation of Lrp6, a co-receptor of the Wnt/beta-catenin signaling pathway, leads to cleft li...
- Evolving enhancer-promoter interactions within the tinman complex of the flour beetle, Tribolium castaneum
[作者：Cande, JD; Chopra, VS; Levine, M,期刊：Development, 页码：3153-3160 , 文章类型： Article，,卷期：2009年136-18]
- Modifications of cis-regulatory DNAs, particularly enhancers, underlie changes in gene expression during animal evolution. Here, we present evidence for a distinct mechanism of regulatory evolution, whereby a novel patte...
- Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm
[作者：Calmont, A; Ivins, S; Van Bueren, KL; Papangeli, I; Kyriakopoulou, V; Andrews, WD; Martin, JF; Moon, AM; Illingworth, EA; Basson, MA; Scambler, PJ,期刊：Development, 页码：3173-3183 , 文章类型： Article，,卷期：2009年136-18]
- Elucidating the gene regulatory networks that govern pharyngeal arch artery (PAA) development is an important goal, as such knowledge can help to identify new genes involved in cardiovascular disease. The transcription f...
- Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development
[作者：Rhee, DY; Zhao, XQ; Francis, RJB; Huang, GY; Mably, JD; Lo, CW,期刊：Development, 页码：3185-3193 , 文章类型： Article，,卷期：2009年136-18]
- Connexin 43 knockout (Cx43 KO) mice exhibit conotruncal malformations and coronary artery defects. We observed epicardial blisters in the Cx43 KO hearts that suggest defects in epicardial epithelial-mesenchymal transform...
- Systematic analysis of dynamic miRNA-target interactions during C. elegans development
[作者：Zhang, L; Hammell, M; Kudlow, BA; Ambros, V; Han, M,期刊：Development, 页码：3043-3055 , 文章类型： Article，,卷期：2009年136-18]
- Although microRNA (miRNA)-mediated functions have been implicated in many aspects of animal development, the majority of miRNA:: mRNA regulatory interactions remain to be characterized experimentally. We used an AIN/GW18...
- Enhancer-promoter communication at the Drosophila engrailed locus
[作者：Kwon, D; Mucci, D; Langlais, KK; Americo, JL; DeVido, SK; Cheng, YZ; Kassis, JA,期刊：Development, 页码：3067-3075 , 文章类型： Article，,卷期：2009年136-18]
- Enhancers are often located many tens of kilobases away from the promoter they regulate, sometimes residing closer to the promoter of a neighboring gene. How do they know which gene to activate? We have used homing P[en]...
- Myosin II regulation during C. elegans embryonic elongation: LET-502/ROCK, MRCK-1 and PAK-1, three kinases with different roles
[作者：Gally, C; Wissler, F; Zahreddine, H; Quintin, S; Landmann, F; Labouesse, M,期刊：Development, 页码：3109-3119 , 文章类型： Article，,卷期：2009年136-18]
- Myosin II plays a central role in epithelial morphogenesis; however, its role has mainly been examined in processes involving a single cell type. Here we analyze the structure, spatial requirement and regulation of myosi...
- Abi plays an opposing role to Abl in Drosophila axonogenesis and synaptogenesis
[作者：Lin, TY; Huang, CH; Kao, HH; Liou, GG; Yeh, SR; Cheng, CM; Chen, MH; Pan, RL; Juang, JL,期刊：Development, 页码：3099-3107 , 文章类型： Article，,卷期：2009年136-18]
- Abl tyrosine kinase (Abl) regulates axon guidance by modulating actin dynamics. Abelson interacting protein (Abi), originally identified as a kinase substrate of Abl, also plays a key role in actin dynamics, yet its role...
- CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing
[作者：Tie, F; Banerjee, R; Stratton, CA; Prasad-Sinha, J; Stepanik, V; Zlobin, A; Diaz, MO; Scacheri, PC; Harte, PJ,期刊：Development, 页码：3131-3141 , 文章类型： Article，,卷期：2009年136-18]
- Trimethylation of histone H3 lysine 27 (H3K27me3) by Polycomb repressive complex 2 (PRC2) is essential for transcriptional silencing of Polycomb target genes, whereas acetylation of H3K27 (H3K27ac) has recently been show...
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