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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共15条记录   Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription [作者：Wang, WG; Lian, N; Li, LZ; Moss, HE; Wang, WX; Perrien, DS; Elefteriou, F; Yang, XL,期刊：Development, 页码：4143-4153 , 文章类型： Article，,卷期：2009年136-24] Activating transcription factor 4 (Atf4) is a leucine-zipper-containing protein of the cAMP response element-binding protein (CREB) family. Ablation of Atf4 (Atf4(-/-)) in mice leads to severe skeletal defects, including... N-cadherin acts in concert with Slit1-Robo2 signaling in regulating aggregation of placode-derived cranial sensory neurons [作者：Shiau, CE; Bronner-Fraser, M,期刊：Development, 页码：4155-4164 , 文章类型： Article，,卷期：2009年136-24] Vertebrate cranial sensory ganglia have a dual origin from the neural crest and ectodermal placodes. In the largest of these, the trigeminal ganglion, Slit1-Robo2 signaling is essential for proper ganglion assembly. Here... The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization [作者：Joeng, KS; Long, FX,期刊：Development, 页码：4177-4185 , 文章类型： Article，,卷期：2009年136-24] Indian hedgehog (Ihh) critically regulates multiple aspects of endochondral bone development. Although it is generally believed that all Ihh functions are mediated by the Gli family of transcription activators and repres... Drosophila laminins act as key regulators of basement membrane assembly and morphogenesis [作者：Urbano, JM; Torgler, CN; Molnar, C; Tepass, U; Lopez-Varea, A; Brown, NH; de Celis, JF; Martin-Bermudo, MD,期刊：Development, 页码：4165-4176 , 文章类型： Article，,卷期：2009年136-24] Laminins are heterotrimeric molecules found in all basement membranes. In mammals, they have been involved in diverse developmental processes, from gastrulation to tissue maintenance. The Drosophila genome encodes two la... Repression of Wasp by JAK/STAT signalling inhibits medial actomyosin network assembly and apical cell constriction in intercalating epithelial cells [作者：Bertet, C; Rauzi, M; Lecuit, T,期刊：Development, 页码：4199-4212 , 文章类型： Article，,卷期：2009年136-24] Tissue morphogenesis requires stereotyped cell shape changes, such as apical cell constriction in the mesoderm and cell intercalation in the ventrolateral ectoderm of Drosophila. Both processes require force generation b... Control in time and space: Tramtrack69 cooperates with Notch and Ecdysone to repress ectopic fate and shape changes during Drosophila egg chamber maturation [作者：Boyle, MJ; Berg, CA,期刊：Development, 页码：4187-4197 , 文章类型： Article，,卷期：2009年136-24] Organ morphogenesis requires cooperation between cells, which determine their course of action based upon location within a tissue. Just as important, cells must synchronize their activities, which requires awareness of ... Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range [作者：Mii, Y; Taira, M,期刊：Development, 页码：4083-4088 , 文章类型： Article，,卷期：2009年136-24] Secreted Frizzled-related proteins (sFRPs) are thought to negatively modulate Wnt signalling. Although Wnt proteins are thought to diffuse extracellularly and act as morphogens, little is known about the diffusibility of... Calmodulin-dependent protein kinase gamma 3 (CamKII gamma 3) mediates the cell cycle resumption of metaphase II eggs in mouse [作者：Chang, HY; Minahan, K; Merriman, JA; Jones, KT,期刊：Development, 页码：4077-4081 , 文章类型： Article，,卷期：2009年136-24] Mature mammalian eggs are ovulated arrested at meiotic metaphase II. Sperm break this arrest by an oscillatory Ca2+ signal that is necessary and sufficient for the two immediate events of egg activation: cell cycle resum... Sanpodo: a context-dependent activator and inhibitor of Notch signaling during asymmetric divisions [作者：Babaoglan, AB; O'Connor-Giles, KM; Mistry, H; Schickedanz, A; Wilson, BA; Skeath, JB,期刊：Development, 页码：4089-4098 , 文章类型： Article，,卷期：2009年136-24] Asymmetric cell divisions generate sibling cells of distinct fates ('A', 'B') and constitute a fundamental mechanism that creates cell-type diversity in multicellular organisms. Antagonistic interactions between the Notc... Cdx2 regulation of posterior development through non-Hox targets [作者：Savory, JGA; Bouchard, N; Pierre, V; Rijli, FM; De Repentigny, Y; Kothary, R; Lohnes, D,期刊：Development, 页码：4099-4110 , 文章类型： Article，,卷期：2009年136-24] The homeodomain transcription factors Cdx1, Cdx2 and Cdx4 play essential roles in anteroposterior vertebral patterning through regulation of Hox gene expression. Cdx2 is also expressed in the trophectoderm commencing at ... Neuropeptide Y functions as a facilitator of GDNF-induced budding of the Wolffian duct [作者：Choi, Y; Tee, JB; Gallegos, TF; Shah, MM; Oishi, H; Sakurai, H; Kitamura, S; Wu, W; Bush, KT; Nigam, SK,期刊：Development, 页码：4213-4224 , 文章类型： Article，,卷期：2009年136-24] Ureteric bud (UB) emergence from the Wolffian duct (WD), the initiating step in metanephric kidney morphogenesis, is dependent on GDNF; however, GDNF by itself is generally insufficient to induce robust budding of the is... Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null mice [作者：Han, J; Mayo, J; Xu, X; Li, JY; Bringas, P; Maas, RL; Rubenstein, JLR; Chai, Y,期刊：Development, 页码：4225-4233 , 文章类型： Article，,卷期：2009年136-24] Cleft palate represents one of the most common congenital birth defects in human. During embryonic development, palatal shelves display oronasal (O-N) and anteroposterior polarity before the onset of fusion, but how the ... Patched regulates Smoothened trafficking using lipoprotein-derived lipids [作者：Khaliullina, H; Panakova, D; Eugster, C; Riedel, F; Carvalho, M; Eaton, S,期刊：Development, 页码：4111-4121 , 文章类型： Article，,卷期：2009年136-24] Hedgehog (Hh) is a lipoprotein-borne ligand that regulates both patterning and proliferation in a wide variety of vertebrate and invertebrate tissues. When Hh is absent, its receptor Patched (Ptc) represses Smoothened (S... The cadherin Fat2 is required for planar cell polarity in the Drosophila ovary [作者：Viktorinova, I; Konig, T; Schlichting, K; Dahmann, C,期刊：Development, 页码：4123-4132 , 文章类型： Article，,卷期：2009年136-24] Planar cell polarity is an important characteristic of many epithelia. In the Drosophila wing, eye and abdomen, establishment of planar cell polarity requires the core planar cell polarity genes and two cadherins, Fat an... Effete-mediated degradation of Cyclin A is essential for the maintenance of germline stem cells in Drosophila [作者：Chen, DS; Wang, Q; Huang, HD; Xia, LX; Jiang, XY; Kan, LJ; Sun, QM; Chen, DH,期刊：Development, 页码：4133-4142 , 文章类型： Article，,卷期：2009年136-24] Increasing evidence supports the idea that the regulation of stem cells requires both extrinsic and intrinsic mechanisms. However, much less is known about how intrinsic signals regulate the fate of stem cells. Studies o...