- Cigarette Smoke-Related Hydroquinone Induces Filamentous Actin Reorganization and Heat Shock Protein 27 Phosphorylation through p38 and Extracellular Signal-Regulated Kinase 1/2 in Retinal Pigment Epithelium Implications for Age-Related Macular Degeneration
[作者：Pons, M; Cousins, SW; Csaky, KG; Striker, G; Marin-Castano, ME,期刊：American Journal of Pathology, 页码：1198-1213 , 文章类型： Article，,卷期：2010年177-3]
- Retinal pigment epithelium (RPE)-derived membranous debris named blebs, may accumulate and contribute to sub-RPE deposit formation, which is the earliest sign of age-related macular degeneration (AMD). Oxidative injury t...
- Acidic Sphingomyelinase Controls Hepatic Stellate Cell Activation and in Vivo Liver Fibrogenesis
[作者：Moles, A; Tarrats, N; Morales, A; Dominguez, M; Bataller, R; Caballeria, J; Garcia-Ruiz, C; Fernandez-Checa, JC; Mari, M,期刊：American Journal of Pathology, 页码：1214-1224 , 文章类型： Article，,卷期：2010年177-3]
- The mechanisms linking hepatocellular death, hepatic stellate cell (HSC) activation, and liver fibrosis are largely unknown. Here, we investigate whether acidic sphingomyelinase (ASMase), a known regulator of death recep...
- Protein Kinase CK1 alpha LS Promotes Vascular Cell Proliferation and Intimal Hyperplasia
[作者：Panchenko, MP; Siddiquee, Z; Dombkowski, DM; Alekseyev, YO; Lenburg, ME; Walker, JD; MacGillivray, TE; Preffer, FI; Stone, JR,期刊：American Journal of Pathology, 页码：1562-1572 , 文章类型： Article，,卷期：2010年177-3]
- Protein kinase CK1 alpha regulates several fundamental cellular processes including proliferation and differentiation. Up to four forms of this kinase are expressed in vertebrates resulting from alternative splicing of e...
- Benefits and Risks of Iron Supplementation in Anemic Neonatal Pigs
[作者：Lipinski, P; Starzynski, RR; Canonne-Hergaux, FS; Tudek, B; Olinski, R; Kowalczyk, P; Dziaman, T; Thibaudeau, O; Gralak, MA; Smuda, E; Wolinski, J; Usinska, A; Zabielski, R,期刊：American Journal of Pathology, 页码：1233-1243 , 文章类型： Article，,卷期：2010年177-3]
- Iron deficiency is a common health problem. The most severe consequence of this disorder is iron deficiency anemia (IDA), which is considered the most common nutritional deficiency worldwide. Newborn piglets are an ideal...
- CD34 Is Required for Infiltration of Eosinophils into the Colon and Pathology Associated with DSS-Induced Ulcerative Colitis
[作者：Maltby, S; Wohlfarth, C; Gold, M; Zbytnuik, L; Hughes, MR; McNagny, KM,期刊：American Journal of Pathology, 页码：1244-1254 , 文章类型： Article，,卷期：2010年177-3]
- Eosinophil migration into the gut and the release of granular mediators plays a critical role in the pathogenesis of inflammatory bowel diseases, including ulcerative colitis. We recently demonstrated that eosinophil mig...
- Cigarette Smoke Induces Epidermal Growth Factor Receptor-Dependent Redistribution of Apical MUC1 and Junctional beta-Catenin in Polarized Human Airway Epithelial Cells
[作者：Chen, YT; Gallup, M; Nikulina, K; Lazarev, S; Zlock, L; Finkbeiner, W; McNamara, N,期刊：American Journal of Pathology, 页码：1255-1264 , 文章类型： Article，,卷期：2010年177-3]
- Cigarette smoke (CS) accounts for nearly 90% of lung cancer deaths worldwide; however, an incomplete understanding of how CS initiates preneoplastic changes in the normal airway hinders early diagnosis. Shot-I.-term expo...
- Interleukin-17 Promotes Early Allograft Inflammation
[作者：Gorbacheva, V; Fan, R; Li, XX; Valujskikh, A,期刊：American Journal of Pathology, 页码：1265-1273 , 文章类型： Article，,卷期：2010年177-3]
Acute cellular rejection of organ transplants is executed by donor-reactive T cells, which are dominated by interferon gamma-producing cells. As interferon-gamma is dispensable for graft destruction, we evaluated the ...
- Simian Immunodeficiency Virus Infection Alters Chemokine Networks in Lung Tissues of Cynomolgus Macaques Association with Pneumocystis carinii Infection
[作者：Qin, SL; Junecko, BAF; Trichel, AM; Tanwater, PM; Murphey-Corb, MA; Kirschner, DE; Reinhart, TA,期刊：American Journal of Pathology, 页码：1274-1285 , 文章类型： Article，,卷期：2010年177-3]
- Infection by HIV-1 frequently leads to pulmonary complications, including alterations to local immune environments. To better understand these alterations, we have examined in detail the patterns and levels of expression...
- Neurokinin-1 Receptor (NK1-R) Expression in the Brains of SIV-Infected Rhesus Macaques Implications for Substance P in NK1-R Immune Cell Trafficking into the CNS
[作者：Vinet-Oliphant, H; Alvarez, X; Buza, E; Borda, JT; Mohan, M; Aye, PP; Tuluc, F; Douglas, SD; Lackner, AA,期刊：American Journal of Pathology, 页码：1286-1297 , 文章类型： Article，,卷期：2010年177-3]
- Recent studies suggest a link between neuropsychiatric disorders and HIV/SIV infection. Most evidence indicates that monocytes/macrophages are the primary cell type infected within the CNS and that they contribute to CNS...
- Antibody Treatment Promotes Compensation for Human Cytomegalovirus-Induced Pathogenesis and a Hypoxia-Like Condition in Placentas with Congenital Infection
[作者：Maidji, E; Nigro, G; Tabata, T; McDonagh, S; Nozawa, N; Shiboski, S; Muci, S; Anceschi, MM; Aziz, N; Adler, SP; Pereira, L,期刊：American Journal of Pathology, 页码：1298-1310 , 文章类型： Article，,卷期：2010年177-3]
- Human cytomegalovirus (HCMV) is the major viral cause of birth defects worldwide. Affected infants can have temporary symptoms that resolve soon after birth, such as growth restriction, and permanent disabilities, includ...
- Liver Xeno-Repopulation with Human Hepatocytes in Fah(-/-) Rag2(-/-) Mice after Pharmacological Immunosuppression
[作者：He, ZY; Zhang, HB; Zhang, X; Xie, DF; Chen, YX; Wangensteen, KJ; Ekker, SC; Firpo, M; Liu, CC; Xiang, D; Zi, XY; Hui, LJ; Yang, GS; Ding, XY; Fu, YP; Wang, X,期刊：American Journal of Pathology, 页码：1311-1319 , 文章类型： Article，,卷期：2010年177-3]
- Functional human hepatocytes xeno-engrafted in mouse liver can be used as a model system to study hepatitis virus infection and vaccine efficacy. Significant liver xeno-repopulation has been reported in two kinds of gene...
- Osteopontin Mediates Citrobacter rodentium-Induced Colonic Epithelial Cell Hyperplasia and Attaching-Effacing Lesions
[作者：Wine, E; Shen-Tu, G; Gareau, MG; Goldberg, HA; Licht, C; Ngan, BY; Sorensen, ES; Greenaway, J; Sodek, J; Zohar, R; Sherman, PM,期刊：American Journal of Pathology, 页码：1320-1332 , 文章类型： Article，,卷期：2010年177-3]
- Although osteopontin (OPN) is up-regulated in inflammatory bowel diseases, its role in disease pathogenesis remains controversial. The objective of this study was to determine the role of OPN in host responses to a non-i...
- Interleukin-1 as a Phenotypic Immunomodulator in Keratinizing Squamous Metaplasia of the Ocular Surface in Sjogren's Syndrome
[作者：Chen, YT; Nikulina, K; Lazarev, S; Bahrami, AF; Noble, LB; Gallup, M; McNamara, NA,期刊：American Journal of Pathology, 页码：1333-1343 , 文章类型： Article，,卷期：2010年177-3]
Chronic inflammation of the ocular surface in Sjogren's syndrome (SS) is associated with a vision-threatening, phenotypic change of the ocular surface, which converts from a nonkeratinized, stratified squamous epithel...
|