- Intracellular Localization and Routing of miRNA and RNAi Pathway Components
[作者:Ohrt, T; Muetze, J; Svoboda, P; Schwille, P,期刊:Current Topics in Medicinal Chemistry, 页码:79-88 , 文章类型: Review,,卷期:2012年12-2]
- Several different pathways, generally termed RNA silencing pathways, utilize small RNA molecules guiding sequence-specific silencing effects of ribonucleoprotein effector complexes, traditionally termed RNA-induced silen...
- Matrix Systems for siRNA Delivery
[作者:Naeye, B; Raemdonck, K; Remaut, K; Demeester, J; De Smedt, SC,期刊:Current Topics in Medicinal Chemistry, 页码:89-96 , 文章类型: Review,,卷期:2012年12-2]
- Over the last decade, considerable effort has been put in the implementation of RNA interference (RNAi) as a treatment for various disorders. As RNAi occurs in the cytoplasm of cells, it is imperative that RNAi mediators...
- Polymeric Carrier Systems for siRNA Delivery
[作者:Vader, P; van der Aa, LJ; Storm, G; Schiffelers, RM; Engbersen, JFJ,期刊:Current Topics in Medicinal Chemistry, 页码:108-119 , 文章类型: Review,,卷期:2012年12-2]
- RNA interference is a technique to induce sequence-specific gene silencing, but is hampered by inefficient delivery of its mediator, short interfering RNA, into target cells. This review describes recent advances in siRN...
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