- Inhibition of Plasminogen Activator Inhibitor-1 Restores Skeletal Muscle Regeneration in Untreated Type 1 Diabetic Mice
[作者：Krause, MP; Moradi, J; Nissar, AA; Riddell, MC; Hawke, TJ,期刊：Diabetes, 页码：1964-1972 , 文章类型： Article，,卷期：2011年60-7]
- OBJECTIVE-Type 1 diabetes leads to impairments in growth, function, and regenerative capacity of skeletal muscle; however, the underlying mechanisms have not been clearly defined. RESEARCH DESIGN AND METHODS-With the use...
- Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity A Possible Contributor to Increased Risk of Cardiovascular Disease in Diabetes
[作者：Rabbani, N; Godfrey, L; Xue, MZ; Shaheen, F; Geoffrion, M; Milne, R; Thornalley, PJ,期刊：Diabetes, 页码：1973-1980 , 文章类型： Article，,卷期：2011年60-7]
- OBJECTIVE-To study whether modification of LDL by methylglyoxal (MG), a potent arginine-directed glycating agent that is increased in diabetes, is associated with increased atherogenicity. RESEARCH DESIGN AND METHODS-Hum...
- Transcriptional Profiling of Diabetic Neuropathy in the BKS db/db Mouse A Model of Type 2 Diabetes
[作者：Pande, M; Hur, J; Hong, Y; Backus, C; Hayes, JM; Oh, SS; Kretzler, M; Feldman, EL,期刊：Diabetes, 页码：1981-1989 , 文章类型： Article，,卷期：2011年60-7]
- OBJECTIVE-A better understanding of the molecular mechanisms underlying the development and progression of diabetic neuropathy (DN) is essential for the design of mechanism-based therapies. We examined changes in global ...
- Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity
[作者：Prawitt, J; Abdelkarim, M; Stroeve, JHM; Popescu, I; Duez, H; Velagapudi, VR; Dumont, J; Bouchaert, E; van Dijk, TH; Lucas, A; Dorchies, E; Daoudi, M; Lestavel, S; Gonzalez, FJ; Oresic, M; Cariou, B; Kuipers, F; Caron, S; Staels, B,期刊：Diabetes, 页码：1861-1871 , 文章类型： Article，,卷期：2011年60-7]
- OBJECTIVE-Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through different signaling pathways. The nuclear BA receptor farnesoid X receptor (FXR) regulates pathways in BA, lipid, glucose, ...
- Suppression of FoxO1 Activity by Long-Chain Fatty Acyl Analogs
[作者：Zatara, G; Hertz, R; Shaked, M; Mayorek, N; Morad, E; Grad, E; Cahan, A; Danenberg, HD; Unterman, TG; Bar-Tana, J,期刊：Diabetes, 页码：1872-1881 , 文章类型： Article，,卷期：2011年60-7]
- OBJECTIVE-Overactivity of the Forkhead transcription factor FoxO1 promotes diabetic hyperglycemia, dyslipidemia, and acutephase response, whereas suppression of FoxO1 activity by insulin may alleviate diabetes. The repor...
- Metabolic Remodeling of Human Skeletal Myocytes by Cocultured Adipocytes Depends on the Lipolytic State of the System
[作者：Kovalik, JP; Slentz, D; Stevens, RD; Kraus, WE; Houmard, JA; Nicoll, JB; Lea-Currie, YR; Everingham, K; Kien, CL; Buehrer, BM; Muoio, DM,期刊：Diabetes, 页码：1882-1893 , 文章类型： Article，,卷期：2011年60-7]
- OBJECTIVE-Adipocyte infiltration of the musculoskeletal system is well recognized as a hallmark of aging, obesity, and type 2 diabetes. Intermuscular adipocytes might serve as a benign storage site for surplus lipid or p...
- Comparison of Dorsocervical With Abdominal Subcutaneous Adipose Tissue in Patients With and Without Antiretroviral Therapy-Associated Lipodystrophy
[作者：Sevastianova, K; Sutinen, J; Greco, D; Sievers, M; Salmenkivi, K; Perttila, J; Olkkonen, VM; Wagsater, D; Lidell, ME; Enerback, S; Eriksson, P; Walker, UA; Auvinen, P; Ristola, M; Yki-Jarvinen, H,期刊：Diabetes, 页码：1894-1900 , 文章类型： Article，,卷期：2011年60-7]
- OBJECTIVE-Combination antiretroviral therapy (cART) is associated with lipodystrophy, i.e., loss of subcutaneous adipose tissue in the abdomen, limbs, and face and its accumulation intra-abdominally. No fat is lost dorso...
- Glucose Transporter-1 in the Hypothalamic Glial Cells Mediates Glucose Sensing to Regulate Glucose Production In Vivo
[作者：Chari, M; Yang, CS; Lam, CKL; Lee, K; Mighiu, P; Kokorovic, A; Cheung, GWC; Lai, TYY; Wang, PYT; Lam, TKT,期刊：Diabetes, 页码：1901-1906 , 文章类型： Article，,卷期：2011年60-7]
- OBJECTIVE-Circulating glucose inhibits glucose production in normal rodents and humans, but this glucose effectiveness is disrupted in diabetes due partly to sustained hyperglycemia. We hypothesize that hyperglycemia in ...
- Klotho Depletion Contributes to Increased Inflammation in Kidney of the db/db Mouse Model of Diabetes via RelA (Serine)(536) Phosphorylation
[作者：Zhao, YH; Banerjee, S; Dey, N; LeJeune, WS; Sarkar, PS; Brobey, R; Rosenblatt, KP; Tilton, RG; Choudhary, S,期刊：Diabetes, 页码：1907-1916 , 文章类型： Article，,卷期：2011年60-7]
- OBJECTIVE-Klotho is an antiaging hormone present in the kidney that extends the lifespan, regulates kidney function, and modulates cellular responses to oxidative stress. We investigated whether Klotho levels and signali...
- Dipeptidyl Peptidase 4 Is a Novel Adipokine Potentially Linking Obesity to the Metabolic Syndrome
[作者：Lamers, D; Famulla, S; Wronkowitz, N; Hartwig, S; Lehr, S; Ouwens, DM; Eckardt, K; Kaufman, JM; Ryden, M; Muller, S; Hanisch, FG; Ruige, J; Arner, P; Sell, H; Eckel, J,期刊：Diabetes, 页码：1917-1925 , 文章类型： Article，,卷期：2011年60-7]
- OBJECTIVE-Comprehensive proteomic profiling of the human adipocyte secretome identified dipeptidyl peptidase 4 (DPP4) as a novel adipoldne. This study assessed the functional implications of the adipokine DPP4 and its as...
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