- Iron Overload and Diabetes Risk: A Shift From Glucose to Fatty Acid Oxidation and Increased Hepatic Glucose Production in a Mouse Model of Hereditary Hemochromatosis
[作者：Huang, JY; Jones, D; Luo, B; Sanderson, M; Soto, J; Abel, ED; Cooksey, RC; McClain, DA,期刊：Diabetes, 页码：80-87 , 文章类型： Article，,卷期：2011年60-1]
- OBJECTIVE Excess tissue iron levels are a risk factor for diabetes, but the mechanisms underlying the association are incompletely understood. We previously published that mice and humans with a form of hereditary iron o...
- Basal and Insulin Mediated VLDL-Triglyceride Kinetics in Type 2 Diabetic Men
[作者：Sorensen, LP; Andersen, IR; Sondergaard, E; Gormsen, LC; Schmitz, O; Christiansen, JS; Nielsen, S,期刊：Diabetes, 页码：88-96 , 文章类型： Article，,卷期：2011年60-1]
- OBJECTIVE Increased very-low-density lipoprotein triglycerides (VLDL-TG) concentration is a central feature of diabetic dyslipidemia. The objective was to compare basal and insulin mediated VLDL-TG kinetics, oxidation, a...
- Enhanced Energy Expenditure, Glucose Utilization, and Insulin Sensitivity in VAMP8 Null Mice
[作者：Zong, HH; Wang, CC; Vaitheesvaran, B; Kurland, IJ; Hong, WJ; Pessin, JE,期刊：Diabetes, 页码：30-38 , 文章类型： Article，,卷期：2011年60-1]
- OBJECTIVE Previous studies have demonstrated that the VAMP8 protein plays a complex role in the control of granule secretion, transport vesicle trafficking, phagocytosis, and endocytosis. The present study was aimed to i...
- Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity A Driver for Ectopic Fat Deposition?
[作者：McQuaid, SE; Hodson, L; Neville, MJ; Dennis, AL; Cheeseman, J; Humphreys, SM; Ruge, T; Gilbert, M; Fielding, BA; Frayn, KN; Karpe, F,期刊：Diabetes, 页码：47-55 , 文章类型： Article，,卷期：2011年60-1]
- OBJECTIVE Lipotoxicity and ectopic fat deposition reduce insulin signaling. It is not clear whether excess fat deposition in nonadipose tissue arises from excessive fatty acid delivery from adipose tissue or from impaire...
- Lipid-Induced Insulin Resistance Affects Women Less Than Men and Is Not Accompanied by Inflammation or Impaired Proximal Insulin Signaling
[作者：Hoeg, LD; Sjoberg, KA; Jeppesen, J; Jensen, TE; Frosig, C; Birk, JB; Bisiani, B; Hiscock, N; Pilegaard, H; Wojtaszewski, JFP; Richter, EA; Kiens, B,期刊：Diabetes, 页码：64-73 , 文章类型： Article，,卷期：2011年60-1]
- OBJECTIVE We have previously shown that overnight fasted women have higher insulin-stimulated whole body and leg glucose uptake despite a higher intramyocellular triacylglycerol concentration than men. Women also express...
- Changes in Alcohol Consumption and Subsequent Risk of Type 2 Diabetes in Men
[作者：Joosten, MM; Chiuve, SE; Mukamal, KJ; Hu, FB; Hendriks, HFJ; Rimm, EB,期刊：Diabetes, 页码：74-79 , 文章类型： Article，,卷期：2011年60-1]
- OBJECTIVE The objective of this study was to investigate the association of 4-year changes in alcohol consumption with a subsequent risk of type 2 diabetes. RESEARCH DESIGN AND METHODS We prospectively examined 38,031 me...
- Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targeting of SHP1 Tyrosine Phosphatase
[作者：Oriente, F; Iovino, S; Cabaro, S; Cassese, A; Longobardi, E; Miele, C; Ungaro, P; Formisano, P; Blasi, F; Beguinot, F,期刊：Diabetes, 页码：138-147 , 文章类型： Article，,卷期：2011年60-1]
- OBJECTIVE We investigated the function of the Prep1 gene in insulin-dependent glucose homeostasis in liver. RESEARCH DESIGN AND METHODS Prep l action on insulin glucoregulatory function has been analyzed in liver of Prep...
- OCT1 Expression in Adipocytes Could Contribute to Increased Metformin Action in Obese Subjects
[作者：Moreno-Navarrete, JM; Ortega, FJ; Rodriguez-Hermosa, JI; Sabater, M; Pardo, G; Ricart, W; Fernandez-Real, JM,期刊：Diabetes, 页码：168-176 , 文章类型： Article，,卷期：2011年60-1]
- OBJECTIVE Metformin has been well characterized in vitro as a substrate of liver-expressed organic cation transporters (OCTs). We investigated the gene expression and protein levels of OCT-1 and OCT-2 in adipose tissue a...
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