- The Role of LAT in Increased CD8(+) T Cell Exhaustion in Trigeminal Ganglia of Mice Latently Infected with Herpes Simplex Virus 1
[作者:Allen, SJ; Hamrah, P; Gate, D; Mott, KR; Mantopoulos, D; Zheng, LX; Town, T; Jones, C; von Andrian, UH; Freeman, GJ; Sharpe, AH; BenMohamed, L; Ahmed, R; Wechsler, SL; Ghiasi, H,期刊:Journal of virology, 页码:4184-4197 , 文章类型: Article,,卷期:2011年85-9]
- Herpes simplex virus (HSV) infection is a classic example of latent viral infection in humans and experimental animal models. The HSV-1 latency-associated transcript (LAT) plays a major role in the HSV-1 latency reactiva...
- Role of Endosomes in Simian Virus 40 Entry and Infection
[作者:Engel, S; Heger, T; Mancini, R; Herzog, F; Kartenbeck, J; Hayer, A; Helenius, A,期刊:Journal of virology, 页码:4198-4211 , 文章类型: Article,,卷期:2011年85-9]
- After binding to its cell surface receptor ganglioside GM1, simian virus 40 (SV40) is endocytosed by lipid raft-mediated endocytosis and slowly transported to the endoplasmic reticulum, where partial uncoating occurs. We...
- Biological Effects and Use of PrPSc- and PrP-Specific Antibodies Generated by Immunization with Purified Full-Length Native Mouse Prions
[作者:Petsch, B; Muller-Schiffmann, A; Lehle, A; Zirdum, E; Prikulis, I; Kuhn, F; Raeber, AJ; Ironside, JW; Korth, C; Stitz, L,期刊:Journal of virology, 页码:4538-4546 , 文章类型: Article,,卷期:2011年85-9]
- The prion agent is the infectious particle causing spongiform encephalopathies in animals and humans and is thought to consist of an altered conformation (PrPSc) of the normal and ubiquitous prion protein PrPC. The inter...
- Infection, Viral Dissemination, and Antibody Responses of Rhesus Macaques Exposed to the Human Gammaretrovirus XMRV
[作者:Onlamoon, N; Das Gupta, J; Sharma, P; Rogers, K; Suppiah, S; Rhea, J; Molinaro, RJ; Gaughan, C; Dong, BH; Klein, EA; Qiu, XX; Devare, S; Schochetman, G; Hackett, J; Silverman, RH; Villinger, F,期刊:Journal of virology, 页码:4547-4557 , 文章类型: Article,,卷期:2011年85-9]
- Xenotropic murine leukemia-related virus (XMRV) was identified in association with human prostate cancer and chronic fatigue syndrome. To examine the infection potential, kinetics, and tissue distribution of XMRV in an a...
- Environmental and Antigen Receptor-Derived Signals Support Sustained Surveillance of the Lungs by Pathogen-Specific Cytotoxic T Lymphocytes
[作者:Lee, YT; Suarez-Ramirez, JE; Wu, T; Redman, JM; Bouchard, K; Hadley, GA; Cauley, LS,期刊:Journal of virology, 页码:4085-4094 , 文章类型: Article,,卷期:2011年85-9]
- Viral infections often gain access to the body of their host by exploiting areas of natural vulnerability, such as the semipermeable surfaces of mucosal tissues which are adapted for adsorption of nutrients and other dif...
- Mutagenesis of Varicella-Zoster Virus Glycoprotein I (gI) Identifies a Cysteine Residue Critical for gE/gI Heterodimer Formation, gI Structure, and Virulence in Skin Cells
[作者:Oliver, SL; Sommer, MH; Reichelt, M; Rajamani, J; Vlaycheva-Beisheim, L; Stamatis, S; Cheng, J; Jones, C; Zehnder, J; Arvin, AM,期刊:Journal of virology, 页码:4095-4110 , 文章类型: Article,,卷期:2011年85-9]
- Varicella-zoster virus (VZV) is the alphaherpesvirus that causes chicken pox (varicella) and shingles (zoster). The two VZV glycoproteins gE and gI form a heterodimer that mediates efficient cell-to-cell spread. Deletion...
- On the Role of the SP1 Domain in HIV-1 Particle Assembly: a Molecular Switch?
[作者:Datta, SAK; Temeselew, LG; Crist, RM; Soheilian, F; Kamata, A; Mirro, J; Harvin, D; Nagashima, K; Cachau, RE; Rein, A,期刊:Journal of virology, 页码:4111-4121 , 文章类型: Article,,卷期:2011年85-9]
- Expression of a retroviral protein, Gag, in mammalian cells is sufficient for assembly of immature virus-like particles (VLPs). VLP assembly is mediated largely by interactions between the capsid (CA) domains of Gag mole...
- Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response
[作者:Glowacka, I; Bertram, S; Muller, MA; Allen, P; Soilleux, E; Pfefferle, S; Steffen, I; Tsegaye, TS; He, YX; Gnirss, K; Niemeyer, D; Schneider, H; Drosten, C; Pohlmann, S,期刊:Journal of virology, 页码:4122-4134 , 文章类型: Article,,卷期:2011年85-9]
- The spike (S) protein of the severe acute respiratory syndrome coronavirus (SARS-CoV) can be proteolytically activated by cathepsins B and L upon viral uptake into target cell endosomes. In contrast, it is largely unknow...
- Early Induction of Autophagy in Human Fibroblasts after Infection with Human Cytomegalovirus or Herpes Simplex Virus 1
[作者:McFarlane, S; Aitken, J; Sutherland, JS; Nicholl, MJ; Preston, VG; Preston, CM,期刊:Journal of virology, 页码:4212-4221 , 文章类型: Article,,卷期:2011年85-9]
- The infection of human fetal foreskin fibroblasts (HFFF2) with human cytomegalovirus (HCMV) resulted in the induction of autophagy. This was demonstrated by the increased lipidation of microtubule-associated protein 1 li...
- Recombinant Adenovirus Serotype 26 (Ad26) and Ad35 Vaccine Vectors Bypass Immunity to Ad5 and Protect Nonhuman Primates against Ebolavirus Challenge
[作者:Geisbert, TW; Bailey, M; Hensley, L; Asiedu, C; Geisbert, J; Stanley, D; Honko, A; Johnson, J; Mulangu, S; Pau, MG; Custers, J; Vellinga, J; Hendriks, J; Jahrling, P; Roederer, M; Goudsmit, J; Koup, R; Sullivan, NJ,期刊:Journal of virology, 页码:4222-4233 , 文章类型: Article,,卷期:2011年85-9]
- The use of adenoviruses (Ad) as vaccine vectors against a variety of pathogens has demonstrated their capacity to elicit strong antibody and cell-mediated immune responses. Adenovirus serotype C vectors, such as Ad serot...
- Immune-Induced Evolutionary Selection Focused on a Single Reading Frame in Overlapping Hepatitis B Virus Proteins
[作者:Maman, Y; Blancher, A; Benichou, J; Yablonka, A; Efroni, S; Louzoun, Y,期刊:Journal of virology, 页码:4558-4566 , 文章类型: Article,,卷期:2011年85-9]
- Viruses employ various means to evade immune detection. Reduction of CD8(+) T cell epitopes is one of the common strategies used for this purpose. Hepatitis B virus (HBV), a member of the Hepadnaviridae family, has four ...
- Distinct Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury Pathways in Two Different Nonhuman Primate Species
[作者:Smits, SL; van den Brand, JMA; de Lang, A; Leijten, LME; van IJcken, WF; van Amerongen, G; Osterhaus, ADME; Andeweg, AC; Haagmans, BL,期刊:Journal of virology, 页码:4234-4245 , 文章类型: Article,,卷期:2011年85-9]
- Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), caused by influenza A virus H5N1 and severe acute respiratory syndrome coronavirus (SARS-CoV), supposedly depend on activation of the oxidative-stre...
- Hepatitis C Patient-Derived Glycoproteins Exhibit Marked Differences in Susceptibility to Serum Neutralizing Antibodies: Genetic Subtype Defines Antigenic but Not Neutralization Serotype
[作者:Tarr, AW; Urbanowicz, RA; Hamed, MR; Albecka, A; McClure, CP; Brown, RJP; Irving, WL; Dubuisson, J; Ball, JK,期刊:Journal of virology, 页码:4246-4257 , 文章类型: Article,,卷期:2011年85-9]
- Neutralizing antibodies have a role in controlling hepatitis C virus (HCV) infection. A successful vaccine will need to elicit potently neutralizing antibodies that are capable of preventing the infection of genetically ...
- Upregulation of Insulin-Like Growth Factor Binding Protein 3 in Astrocytes of Transgenic Mice That Express Borna Disease Virus Phosphoprotein
[作者:Honda, T; Fujino, K; Okuzaki, D; Ohtaki, N; Matsumoto, Y; Horie, M; Daito, T; Itoh, M; Tomonaga, K,期刊:Journal of virology, 页码:4567-4571 , 文章类型: Article,,卷期:2011年85-9]
- In a previous study, we demonstrated that transgenic mice that express Borna disease virus (BDV) phosphoprotein (P) in astrocytes show striking neurobehavioral abnormalities resembling those in BDV-infected animals. To u...
- Mobility and Interactions of Coronavirus Nonstructural Protein 4
[作者:Hagemeijer, MC; Ulasli, M; Vonk, AM; Reggiori, F; Rottier, PJM; de Haan, CAM,期刊:Journal of virology, 页码:4572-4577 , 文章类型: Article,,卷期:2011年85-9]
- Green fluorescent protein (GFP)-tagged mouse hepatitis coronavirus nonstructural protein 4 (nsp4) was shown to localize to the endoplasmic reticulum (ER) and to be recruited to the coronavirus replicative structures. Flu...
- Immunotypes of a Quaternary Site of HIV-1 Vulnerability and Their Recognition by Antibodies
[作者:Wu, XL; Changela, A; O'Dell, S; Schmidt, SD; Pancera, M; Yang, YP; Zhang, BS; Gorny, MK; Phogat, S; Robinson, JE; Stamatatos, L; Zolla-Pazner, S; Kwong, PD; Mascola, JR,期刊:Journal of virology, 页码:4578-4585 , 文章类型: Article,,卷期:2011年85-9]
- HIV-1 is neutralized by a class of antibodies that preferentially recognize a site formed on the assembled viral spike. Such quaternary structure-specific antibodies have diverse neutralization breadths, with antibodies ...
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