- A New Immunostain Algorithm Classifies Diffuse Large B-Cell Lymphoma into Molecular Subtypes with High Accuracy
[作者:Choi, WWL; Weisenburger, DD; Greiner, TC; Piris, MA; Banham, AH; Delabie, J; Braziel, RM; Geng, HM; Iqbal, J; Lenz, G; Vose, JM; Hans, CP; Fu, K; Smith, LM; Li, M; Liu, ZF; Gascoyne, RD; Rosenwald, A; Ott, G; Rimsza, LM; Campo, E; Jaffe, ES; Jaye, DL; Staudt, LM; Chan, WC,期刊:Clinical Cancer Research, 页码:5494-5502 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: Hans and coworkers previously developed an immunohistochemical algorithm with similar to 80% concordance with the gene expression profiling (GEP) classification of diffuse large B-cell lymphoma (DLBCL) into the ...
- [C-11]Choline Positron Emission Tomography in Estrogen Receptor-Positive Breast Cancer
[作者:Contractor, KB; Kenny, LM; Stebbing, J; Al-Nahha, A; Palmieri, C; Sinnett, D; Lewis, JS; Hogben, K; Osman, S; Shousha, S; Lowdell, C; Coombes, RC; Aboagye, EO,期刊:Clinical Cancer Research, 页码:5503-5510 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: Novel radiotracers could potentially allow the identification of clinically aggressive tumor phenotypes. As choline metabolism increases during malignant transformation and progression of human mammary epithelia...
- Decreased Blood Flow with Increased Metabolic Activity: A Novel Sign of Pancreatic Tumor Aggressiveness
[作者:Komar, G; Kauhanen, S; Liukko, K; Seppanen, M; Kajander, S; Ovaska, J; Nuutila, P; Minn, H,期刊:Clinical Cancer Research, 页码:5511-5517 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: To study blood flow (BF) and metabolism in normal pancreas and in different pancreatic lesions. We then determined the effect of these biomarkers on outcome in patients with pancreatic cancer.Experimental Design...
- CD24 Is a Novel Predictor for Poor Prognosis of Hepatocellular Carcinoma after Surgery
[作者:Yang, XR; Xu, Y; Yu, B; Zhou, J; Li, JC; Qiu, SJ; Shi, YH; Wang, XY; Dai, Z; Shi, GM; Wu, B; Wu, LM; Yang, GH; Zhang, BH; Qin, WX; Fan, J,期刊:Clinical Cancer Research, 页码:5518-5527 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: To investigate the role of CD24 in tumor invasion and prognostic significance in hepatocellular carcinoma (HCC).Experimental Design: CD24 expression was measured in stepwise metastatic HCC cell lines, tumor, per...
- Tissue Biomarker Development in a Multicentre Trial Context: a Feasibility Study on the PETACC3 Stage II and III Colon Cancer Adjuvant Treatment Trial
[作者:Bosman, FT; Yan, P; Tejpar, S; Fiocca, R; Van Cutsem, E; Kennedy, RD; Dietrich, D; Roth, A,期刊:Clinical Cancer Research, 页码:5528-5533 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: We evaluated the feasibility of biomarker development in the context of multicenter clinical trials.Experimental Design: Formalin-fixed, paraffin-embedded (FFPE) tissue samples were collected from a prospective ...
- Inflammatory Biomarkers and Fatigue during Radiation Therapy for Breast and Prostate Cancer
[作者:Bower, JE; Ganz, PA; Tao, ML; Hu, WH; Belin, TR; Sepah, S; Cole, S; Aziz, N,期刊:Clinical Cancer Research, 页码:5534-5540 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: Biomarkers of radiation-induced behavioral symptoms, such as fatigue, have not been identified. Studies linking inflammatory processes to fatigue in cancer survivors led us to test the hypothesis that activation...
- Imaging Mass Spectrometry of a Specific Fragment of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Kinase 2 Discriminates Cancer from Uninvolved Prostate Tissue
[作者:Cazares, LH; Troyer, D; Mendrinos, S; Lance, RA; Nyalwidhe, JO; Beydoun, HA; Clements, MA; Drake, RR; Semmes, OJ,期刊:Clinical Cancer Research, 页码:5541-5551 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: Histopathology is the standard approach for tissue diagnostics and center-piece of pathology. Although the current system provides prognostic information, there is need for molecular markers that enhance diagnos...
- Erythropoietin Receptor Expression and Correlation to Tamoxifen Response and Prognosis in Breast Cancer
[作者:Larsson, AM; Jirstrom, K; Fredlund, E; Nilsson, S; Ryden, L; Landberg, G; Pahlman, S,期刊:Clinical Cancer Research, 页码:5552-5559 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: The main function of erythropoietin (EPO) is to stimulate erythropoiesis. EPO receptors (EPOR) are expressed in other cell types, including tumor cells, suggesting that the EPC/EPOR pathway governs additional ce...
- Integration of Molecular Profiling into the Lung Cancer Clinic
[作者:Pao, W; Kris, MG; Iafrate, AJ; Ladanyi, M; Janne, PA; Wistuba, II; Miake-Lye, R; Herbst, RS; Carbone, DP; Johnson, BE; Lynch, TJ,期刊:Clinical Cancer Research, 页码:5317-5322 , 文章类型: Article,,卷期:2009年15-17]
- Individuals from five thoracic oncology centers in the United States recently met to discuss how to integrate molecular profiling into the care of all patients with carcinoma of the lung. Lung cancer is an area of medica...
- The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
[作者:Cheever, MA; Allison, JP; Ferris, AS; Finn, OJ; Hastings, BM; Hecht, TT; Mellman, I; Prindiville, SA; Viner, JL; Weiner, LM; Matrisian, LM,期刊:Clinical Cancer Research, 页码:5323-5337 , 文章类型: Article,,卷期:2009年15-17]
- The purpose of the National Cancer Institute pilot project to prioritize cancer antigens was to develop a well-vetted, priority-ranked list of cancer vaccine target antigens based on predefined and preweighted objective ...
- microRNA Profiling Identifies Cancer-Specific and Prognostic Signatures in Pediatric Malignancies
[作者:Wei, JS; Johansson, P; Chen, QR; Song, YK; Durinck, S; Wen, XY; Cheuk, ATC; Smith, MA; Houghton, P; Morton, C; Khan, J,期刊:Clinical Cancer Research, 页码:5560-5568 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: microRNAs have been shown to be involved indifferent human cancers. We therefore have performed expression profiles on a panel of pediatric tumors to identify cancer-specific microRNAs. We also investigated if m...
- A Phase I Study of a 2-Day Lapatinib Chemosensitization Pulse Preceding Nanoparticle Albumin-Bound Paclitaxel for Advanced Solid Malignancies
[作者:Chien, AJ; Illi, JA; Ko, AH; Korn, WM; Fong, L; Chen, LM; Kashani-Sabet, M; Ryan, CJ; Rosenberg, JE; Dubey, S; Small, EJ; Jahan, TM; Hylton, NM; Yeh, BM; Huang, Y; Koch, KM; Moasser, MM,期刊:Clinical Cancer Research, 页码:5569-5575 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: Systemic chemotherapy fails to access much of the tumor burden in patients with advanced cancer, significantly limiting its efficacy. In preclinical studies, brief high doses of tyrosine kinase inhibitors (TKI) ...
- Cyclin D1 Splice Variants: Polymorphism, Risk, and Isoform-Specific Regulation in Prostate Cancer
[作者:Comstock, CES; Augello, MA; Benito, RP; Karch, J; Tran, TH; Utama, FE; Tindall, EA; Wang, Y; Burd, CJ; Groh, EM; Hoang, HN; Giles, GG; Severi, G; Hayes, VM; Henderson, BE; Le Marchand, L; Kolonel, LN; Haiman, CA; Baffa, R; Gomella, LG; Knudsen, ES; Rui, H; Henshall, SM; Sutherland, RL; Knudsen, KE,期刊:Clinical Cancer Research, 页码:5338-5349 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: Alternative CCND1 splicing results in cyclin D1b, which has specialized, pro-tumorigenic functions in prostate not shared by the cyclin D1a (full length) isoform. Here, the frequency, tumor relevance, and mechan...
- Expression of EBV Latent Antigens, Mammalian Target of Rapamycin, and Tumor Suppression Genes in EBV-Positive Smooth Muscle Tumors: Clinical and Therapeutic Implications
[作者:Ong, KW; Teo, M; Lee, V; Ong, D; Lee, A; Tan, CS; Vathsala, A; Toh, HC,期刊:Clinical Cancer Research, 页码:5350-5358 , 文章类型: Article,,卷期:2009年15-17]
- Purpose: EBV-positive smooth muscle tumor (EBV+SMT) is a rare disease with no established therapy. We describe the largest single institution analysis in renal transplant recipients. It aims to define its clinical featur...
|