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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共16条记录   Connecting with Ska, a key complex at the kinetochore-microtubule interface [作者：Guimaraes, GJ; DeLuca, JG,期刊：EMBO journal, 页码：1375-1377 , 文章类型： Article，,卷期：2009年28-10] The highly orchestrated movements of chromosomes during mitosis depend on the formation of stable connections between microtubules and kinetochores. How kinetochores generate these linkages to harness the forces produced... How do we feel? [作者：Drew, LJ,期刊：EMBO journal, 页码：1378-1379 , 文章类型： Article，,卷期：2009年28-10] Mammalian dorsal root ganglia (DRG) contain a diverse collection of sensory neuronal subtypes specialized to detect different sensory stimuli. Most of these cells respond to mechanical stimulation of some sort, be they p... Glycosylation defects activate filamentous growth Kss1 MAPK and inhibit osmoregulatory Hog1 MAPK [作者：Yang, HY; Tatebayashi, K; Yamamoto, K; Saito, H,期刊：EMBO journal, 页码：1380-1391 , 文章类型： Article，,卷期：2009年28-10] The yeast filamentous growth (FG) MAP kinase (MAPK) pathway is activated under poor nutritional conditions. We found that the FG-specific Kss1 MAPK is activated by a combination of an O-glycosylation defect caused by dis... MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells [作者：Schwermann, J; Rathinam, C; Schubert, M; Schumacher, S; Noyan, F; Koseki, H; Kotlyarov, A; Klein, C; Gaestel, M,期刊：EMBO journal, 页码：1392-1406 , 文章类型： Article，,卷期：2009年28-10] The structurally related MAPK-activated protein kinases (MAPKAPKs or MKs) MK2, MK3 and MK5 are involved in multiple cellular functions, including cell-cycle control and cellular differentiation. Here, we show that after ... Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells [作者：Cho, SY; Schroeder, S; Kaehlcke, K; Kwon, HS; Pedal, A; Herker, E; Schnoelzer, M; Ott, M,期刊：EMBO journal, 页码：1407-1417 , 文章类型： Article，,卷期：2009年28-10] The elongation competence of the RNA polymerase II complex is critically dependent on the positive transcription elongation factor b (P-TEFb). P-TEFb exists in two forms in cells, an active form composed of cyclin T1 and... ChIP-Seq of ER alpha and RNA polymerase II defines genes differentially responding to ligands [作者：Welboren, WJ; van Driel, MA; Janssen-Megens, EM; van Heeringen, SJ; Sweep, FCGJ; Span, PN; Stunnenberg, HG,期刊：EMBO journal, 页码：1418-1428 , 文章类型： Article，,卷期：2009年28-10] We used ChIP-Seq to map ER alpha-binding sites and to profile changes in RNA polymerase II (RNAPII) occupancy in MCF-7 cells in response to estradiol (E2), tamoxifen or fulvestrant. We identify 10 205 high confidence ER ... Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control [作者：Deplazes, A; Mockli, N; Luke, B; Auerbach, D; Peter, M,期刊：EMBO journal, 页码：1429-1441 , 文章类型： Article，,卷期：2009年28-10] Translation initiation in eukaryotes is accomplished by a large set of translation initiation factors, some of which are regulated by signals monitoring intracellular and environmental conditions. Here, we show that Uri1... Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3 [作者：Gaitanos, TN; Santamaria, A; Jeyaprakash, AA; Wang, B; Conti, E; Nigg, EA,期刊：EMBO journal, 页码：1442-1452 , 文章类型： Article，,卷期：2009年28-10] Ska1 and Ska2 form a complex at the kinetochore-microtubule (KT-MT) interface and are required for timely progression from metaphase to anaphase. Here, we use mass spectrometry to search for additional components of the ... Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division [作者：Theis, M; Slabicki, M; Junqueira, M; Paszkowski-Rogacz, M; Sontheimer, J; Kittler, R; Heninger, AK; Glatter, T; Kruusmaa, K; Poser, I; Hyman, AA; Pisabarro, MT; Gstaiger, M; Aebersold, R; Shevchenko, A; Buchholz, F,期刊：EMBO journal, 页码：1453-1465 , 文章类型： Article，,卷期：2009年28-10] Proliferation of mammalian cells requires the coordinated function of many proteins to accurately divide a cell into two daughter cells. Several RNAi screens have identified previously uncharacterised genes that are impl... Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replication [作者：Meng, FL; Hu, Y; Shen, N; Tong, XJ; Wang, JY; Ding, JP; Zhou, JQ,期刊：EMBO journal, 页码：1466-1478 , 文章类型： Article，,卷期：2009年28-10] In budding yeast Saccharomyces cerevisiae, telomere length maintenance involves a complicated network as more than 280 telomere maintenance genes have been identified in the nonessential gene deletion mutant set. As a su... Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development [作者：Lechner, SG; Frenzel, H; Wang, R; Lewin, GR,期刊：EMBO journal, 页码：1479-1491 , 文章类型： Article，,卷期：2009年28-10] Somatic sensation relies on the transduction of physical stimuli into electrical signals by sensory neurons of the dorsal root ganglia. Little is known about how and when during development different types of sensory neu... Reduced c-Myb activity compromises HSCs and leads to a myeloproliferation with a novel stem cell basis [作者：Garcia, P; Clarke, M; Vegiopoulos, A; Berlanga, O; Camelo, A; Lorvellec, M; Frampton, J,期刊：EMBO journal, 页码：1492-1504 , 文章类型： Article，,卷期：2009年28-10] Murine haematopoietic stem cells (HSCs) are contained in the Kit(+)Sca1(+)Lin(-) (KSL) population of bone marrow and are able to repopulate lethally irradiated mice. Myeloproliferative disorders (MPDs) are thought to be ... Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity [作者：Cao, JX; Schulte, J; Knight, A; Leslie, NR; Zagozdzon, A; Bronson, R; Manevich, Y; Beeson, C; Neumann, CA,期刊：EMBO journal, 页码：1505-1517 , 文章类型： Article，,卷期：2009年28-10] It is widely accepted that reactive oxygen species (ROS) promote tumorigenesis. However, the exact mechanisms are still unclear. As mice lacking the peroxidase peroxiredoxin1 (Prdx1) produce more cellular ROS and die pre... Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization [作者：Chaudhry, C; Weston, MC; Schuck, P; Rosenmund, C; Mayer, ML,期刊：EMBO journal, 页码：1518-1530 , 文章类型： Article，,卷期：2009年28-10] AMPA and kainate receptors mediate fast synaptic transmission. AMPA receptor ligand-binding domains form dimers, which are key functional units controlling ion-channel activation and desensitization. Dimer stability is i... An unsteady scaffold for Myc (vol 28, pg 453, 2009) [作者：Schulein, C; Eilers, M,期刊：EMBO journal, 页码：1531-1531 , 文章类型： Correction，,卷期：2009年28-10] TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells (vol 28, pg 677, 2009) [作者：Herrero-Martin, G; Hoyer-Hansen, M; Garcia-Garcia, C; Fumarola, C; Farkas, T; Lopez-Rivas, A; Jaattela, M,期刊：EMBO journal, 页码：1532-1532 , 文章类型： Correction，,卷期：2009年28-10]