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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共23条记录   Loss of Scribble causes cell competition in mammalian cells [作者：Norman, M; Wisniewska, KA; Lawrenson, K; Garcia-Miranda, P; Tada, M; Kajita, M; Mano, H; Ishikawa, S; Ikegawa, M; Shimada, T; Fujita, Y,期刊：Journal of cell science, 页码：59-66 , 文章类型： Article，,卷期：2012年125-1] In Drosophila, normal and transformed cells compete with each other for survival in a process called cell competition. However, it is not known whether comparable phenomena also occur in mammals. Scribble is a tumor supp... MicroRNAs and their roles in aging [作者：Smith-Vikos, T; Slack, FJ,期刊：Journal of cell science, 页码：7-17 , 文章类型： Article，,卷期：2012年125-1] MicroRNAs (miRNAs) are a class of short non-coding RNAs that bind mRNAs through partial base-pair complementarity with their target genes, resulting in post-transcriptional repression of gene expression. The role of miRN... The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain [作者：Lobert, VH; Stenmark, H,期刊：Journal of cell science, 页码：29-36 , 文章类型： Article，,卷期：2012年125-1] Recent evidence implicates the endosomal sorting complex required for transport (ESCRT) in the regulation of epithelial polarity in Drosophila melanogaster, but the mechanisms responsible for this action remain unclear. ... Cdt1p, through its interaction with Mcm6p, is required for the formation, nuclear accumulation and chromatin loading of the MCM complex [作者：Wu, RT; Wang, JF; Liang, C,期刊：Journal of cell science, 页码：209-219 , 文章类型： Article，,卷期：2012年125-1] Regulation of DNA replication initiation is essential for the faithful inheritance of genetic information. Replication initiation is a multi-step process involving many factors including ORC, Cdt1p, Mcm2-7p and other pro... The integrator complex is required for integrity of Cajal bodies [作者：Takata, H; Nishijima, H; Maeshima, K; Shibahara, K,期刊：Journal of cell science, 页码：166-175 , 文章类型： Article，,卷期：2012年125-1] The nucleus in eukaryotic cells is a highly organized and dynamic structure containing numerous subnuclear bodies. The morphological appearance of nuclear bodies seems to be a reflection of ongoing functions, such as DNA... Mutational analysis supports a core role for Drosophila alpha-Catenin in adherens junction function [作者：Sarpal, R; Pellikka, M; Patel, RR; Hui, FYW; Godt, D; Tepass, U,期刊：Journal of cell science, 页码：233-245 , 文章类型： Article，,卷期：2012年125-1] alpha-catenin associates the cadherin-catenin complex with the actin cytoskeleton. a-catenin binds to beta-catenin, which links it to the cadherin cytoplasmic tail, and F-actin, but also to a multitude of actin-associate... The MCM-associated protein MCM-BP is important for human nuclear morphology [作者：Jagannathan, M; Sakwe, AM; Nguyen, T; Frappier, L,期刊：Journal of cell science, 页码：133-143 , 文章类型： Article，,卷期：2012年125-1] Mini-chromosome maintenance complex-binding protein (MCM-BP) was discovered as a protein that is strongly associated with human MCM proteins, known to be crucial for DNA replication in providing DNA helicase activity. Th... Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability [作者：Kumareswaran, R; Ludkovski, O; Meng, A; Sykes, J; Pintilie, M; Bristow, RG,期刊：Journal of cell science, 页码：189-199 , 文章类型： Article，,卷期：2012年125-1] Hypoxic cells have been linked to genetic instability and tumor progression. However, little is known about the exact relationship between DNA repair and genetic instability in hypoxic cells. We therefore tested whether ... The nucleoporin-like protein NLP1 (hCG1) promotes CRM1-dependent nuclear protein export [作者：Waldmann, I; Spillner, C; Kehlenbach, RH,期刊：Journal of cell science, 页码：144-154 , 文章类型： Article，,卷期：2012年125-1] Translocation of transport complexes across the nuclear envelope is mediated by nucleoporins, proteins of the nuclear pore complex that contain phenylalanine-glycine (FG) repeats as a characteristic binding motif for tra... CRSBP-1/LYVE-1 ligands disrupt lymphatic intercellular adhesion by inducing tyrosine phosphorylation and internalization of VE-cadherin (vol 124, pg 1231, 2011) [作者：Hou, WH; Liu, IH; Tsai, CC; Johnson, FE; Huang, SS; Huang, JS,期刊：Journal of cell science, 页码：246-246 , 文章类型： Correction，,卷期：2012年125-1] The role of clathrin in mitotic spindle organisation [作者：Royle, SJ,期刊：Journal of cell science, 页码：19-28 , 文章类型： Article，,卷期：2012年125-1] Clathrin, a protein best known for its role in membrane trafficking, has been recognised for many years as localising to the spindle apparatus during mitosis, but its function at the spindle remained unclear. Recent work... TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing [作者：Rosel, D; Khurana, T; Majithia, A; Huang, XL; Bhandari, R; Kimmel, AR,期刊：Journal of cell science, 页码：37-48 , 文章类型： Article，,卷期：2012年125-1] The TOR protein kinase functions in two distinct complexes, TOR complex 1 (TORC1) and 2 (TORC2). TORC1 is required for growth in response to growth factors, nutrients and the cellular energy state; TORC2 regulates AKT si... Periostin modulates myofibroblast differentiation during full-thickness cutaneous wound repair [作者：Elliott, CG; Wang, J; Guo, XL; Xu, SW; Eastwood, M; Guan, JJ; Leask, A; Conway, SJ; Hamilton, DW,期刊：Journal of cell science, 页码：121-132 , 文章类型： Article，,卷期：2012年125-1] The matricellular protein periostin is expressed in the skin. Although periostin has been hypothesized to contribute to dermal homeostasis and repair, this has not been directly tested. To assess the contribution of peri... Dyrk1A negatively regulates the actin cytoskeleton through threonine phosphorylation of N-WASP [作者：Park, J; Sung, JY; Park, J; Song, WJ; Chang, S; Chung, KC,期刊：Journal of cell science, 页码：67-80 , 文章类型： Article，,卷期：2012年125-1] Neural Wiskott-Aldrich syndrome protein (N-WASP) is involved in tight regulation of actin polymerization and dynamics. N-WASP activity is regulated by intramolecular interaction, binding to small GTPases and tyrosine pho... Quantitative mapping of averaged focal adhesion dynamics in migrating cells by shape normalization [作者：Mohl, C; Kirchgessner, N; Schafer, C; Hoffmann, B; Merkel, R,期刊：Journal of cell science, 页码：155-165 , 文章类型： Article，,卷期：2012年125-1] The spatially ordered formation and disassembly of focal adhesions is a basic requirement for effective cell locomotion. Because focal adhesions couple the contractile actin-myosin network to the substrate, their distrib... Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1 [作者：Gu, W; Katz, Z; Wu, B; Park, HY; Li, DL; Lin, S; Wells, AL; Singer, RH,期刊：Journal of cell science, 页码：81-91 , 文章类型： Article，,卷期：2012年125-1] Metastasis involves tumor cell detachment from the primary tumor, and acquisition of migratory and invasive capabilities. These capabilities are mediated by multiple events, including loss of cell-cell contact, an increa...