- The safety and tolerability evaluation of DepoFoam bupivacaine (bupivacaine extended-release liposome injection) administered by incision wound infiltration in rabbits and dogs
[作者:Richard, BM; Ott, LR; Haan, D; Brubaker, AN; Cole, PI; Nelson, KG; Ross, PE; Rebelatto, MC; Newton, PE,期刊:Expert opinion on investigational drugs, 页码:1327-1341 , 文章类型: Article,,卷期:2011年20-10]
- Objective: DepoFoam(R) bupivacaine (DB) is in development for prolonged postoperative analgesia. Studies were conducted to evaluate the potential local and systemic toxicity and any effect on wound healing after wound in...
- Targeting Mcl-1 for the therapy of cancer
[作者:Quinn, BA; Dash, R; Azab, B; Sarkar, S; Das, SK; Kumar, S; Oyesanya, RA; Dasgupta, S; Dent, P; Grant, S; Rahmani, M; Curiel, DT; Dmitriev, I; Hedvat, M; Wei, J; Wu, BN; Stebbins, JL; Reed, JC; Pellecchia, M; Sarkar, D; Fisher, PB,期刊:Expert opinion on investigational drugs, 页码:1397-1411 , 文章类型: Review,,卷期:2011年20-10]
- Introduction: Human cancers are genetically and epigenetically heterogeneous and have the capacity to commandeer a variety of cellular processes to aid in their survival, growth and resistance to therapy. One strategy is...
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