- Early Atheroma-Derived Agonists of Peroxisome Proliferator-Activated Receptor-gamma Trigger Intramedial Angiogenesis in a Smooth Muscle Cell-Dependent Manner
[作者：Ho-Tin-Noe, B; Le Dall, J; Gomez, D; Louedec, L; Vranckx, R; El-Bouchtaoui, M; Legres, L; Meilhac, O; Michel, JB,期刊：Circulation Research, 页码：1003-NIL_67 , 文章类型： Article，,卷期：2011年109-9]
- Rationale: Neovascularization favors intraplaque hemorrhage and plaque rupture. Development of therapeutic strategies against atheromatous angiogenesis requires elucidation of its initiating factors.Objective: We investi...
- HCN3 Contributes to the Ventricular Action Potential Waveform in the Murine Heart
[作者：Fenske, S; Mader, R; Scharr, A; Paparizos, C; Cao-Ehlker, X; Michalakis, S; Shaltiel, L; Weidinger, M; Stieber, J; Feil, S; Feil, R; Hofmann, F; Wahl-Schott, C; Biel, M,期刊：Circulation Research, 页码：1015-NIL_89 , 文章类型： Article，,卷期：2011年109-9]
- Rationale: The hyperpolarization-activated current I(h) that is generated by hyperpolarization-activated cyclic nucleotide-gated channels (HCNs) plays a key role in the control of pacemaker activity in sinoatrial node ce...
- Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca(2+) Release and Cardiac Contractility, Independently of L-Type Ca(2+) Current
[作者：Beca, S; Helli, PB; Simpson, JA; Zhao, DL; Farman, GP; Jones, PP; Tian, XX; Wilson, LS; Ahmad, F; Chen, SRW; Movsesian, MA; Manganiello, V; Maurice, DH; Conti, M; Backx, PH,期刊：Circulation Research, 页码：1024-NIL_119 , 文章类型： Article，,卷期：2011年109-9]
- Rationale: Baseline contractility of mouse hearts is modulated in a phosphatidylinositol 3-kinase-gamma-dependent manner by type 4 phosphodiesterases (PDE4), which regulate cAMP levels within microdomains containing the ...
- Differential Protein Kinase C Isoform Regulation and Increased Constitutive Activity of Acetylcholine-Regulated Potassium Channels in Atrial Remodeling
[作者：Makary, S; Voigt, N; Maguy, A; Wakili, R; Nishida, K; Harada, M; Dobrev, D; Nattel, S,期刊：Circulation Research, 页码：1031-NIL_140 , 文章类型： Article，,卷期：2011年109-9]
- Rationale: Atrial fibrillation (AF) causes atrial-tachycardia remodeling (ATR), with enhanced constitutive acetylcholine-regulated K(+) current (I(KAChC)) contributing to action potential duration shortening and AF promo...
- Autologous Mesenchymal Stem Cells Mobilize cKit(+) and CD133(+) Bone Marrow Progenitor Cells and Improve Regional Function in Hibernating Myocardium
[作者：Suzuki, G; Iyer, V; Lee, TC; Canty, JM,期刊：Circulation Research, 页码：1044-1054 , 文章类型： Article，,卷期：2011年109-9]
- Rationale: Mesenchymal stem cells (MSCs) improve function after infarction, but their mechanism of action remains unclear, and the importance of reduced scar volume, cardiomyocyte proliferation, and perfusion is uncertai...
- Human Atrial Action Potential and Ca(2+) Model Sinus Rhythm and Chronic Atrial Fibrillation
[作者：Grandi, E; Pandit, SV; Voigt, N; Workman, AJ; Dobrev, D; Jalife, J; Bers, DM,期刊：Circulation Research, 页码：1055-1066 , 文章类型： Article，,卷期：2011年109-9]
- Rationale: Understanding atrial fibrillation (AF) requires integrated understanding of ionic currents and Ca(2+) transport in remodeled human atrium, but appropriate models are limited.Objective: To study AF, we develope...
- Irx3: A Conductor of Conduction
[作者：Kelly, RG,期刊：Circulation Research, 页码：984-985 , 文章类型： Editorial Material，,卷期：2011年109-9]
- Iroquois Homeobox Gene 3 Establishes Fast Conduction in the His-Purkinje Network Zhang et al Proc Natl Acad Sci USA 2011;108:13576-13581.Despite major clinical importance as a cause of arrhythmias, how the transcriptiona...
- Aptamer Neutralization of Beta1-Adrenoceptor Autoantibodies Isolated From Patients With Cardiomyopathies
[作者：Haberland, A; Wallukat, G; Dahmen, C; Kage, A; Schimke, I,期刊：Circulation Research, 页码：986-992 , 文章类型： Article，,卷期：2011年109-9]
- Rationale: Autoantibodies directed against the beta1-adrenoceptor (beta1-AABs) have been proposed to drive the pathogenesis of idiopathic dilated cardiomyoparthy (DCM), Chagas' cardiomyopathy, and peripartum cardiomyopat...
- p63RhoGEF Couples G(alpha q/11)-Mediated Signaling to Ca(2+) Sensitization of Vascular Smooth Muscle Contractility
[作者：Momotani, K; Artamonov, MV; Utepbergenov, D; Derewenda, U; Derewenda, ZS; Somlyo, AV,期刊：Circulation Research, 页码：993-NIL_42 , 文章类型： Article，,卷期：2011年109-9]
- Rationale: In normal and diseased vascular smooth muscle (SM), the RhoA pathway, which is activated by multiple agonists through G protein-coupled receptors (GPCRs), plays a central role in regulating basal tone and peri...
|